Compounds > tanshinone
Page last updated: 2024-09-02

tanshinone and digoxin

tanshinone has been researched along with digoxin in 3 studies

Compound Research Comparison

Studies
(tanshinone)		Trials
(tanshinone)		Recent Studies (post-2010)
(tanshinone)		Studies
(digoxin)		Trials
(digoxin)		Recent Studies (post-2010) (digoxin)
1,445101,03311,4839581,289

Protein Interaction Comparison

ProteinTaxonomytanshinone (IC50)digoxin (IC50)
STAT3, partialHomo sapiens (human)1.862
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)0.32
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)0.0055
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.19
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-1Canis lupus familiaris (dog)0.5
Nuclear receptor ROR-gammaHomo sapiens (human)3.4798
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0055
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.2359

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Liu, PQ; Wen, JY; Yu, XY; Zhou, SF; Zhou, ZW1
Li, XX; Zhou, SF; Zhou, ZW1
Chan, RL; Cho, CH; Hu, T; Li, M; Lu, L; Shen, J; To, KK; Wang, L; Yeung, JH; Zhang, L1

Other Studies

3 other study(ies) available for tanshinone and digoxin

ArticleYear
Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
    Current drug metabolism, 2007, Volume: 8, Issue:4

    Topics: Abietanes; Adenosine Triphosphate; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Digoxin; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Microsomes, Liver; Multidrug Resistance-Associated Proteins; Phenanthrenes; Plant Roots; Probenecid; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Temperature; Transfection; Verapamil

2007
Role of P-glycoprotein in the transport of tanshinone I, one active triterpenoid from Salvia miltiorrhiza.
    Drug metabolism letters, 2008, Volume: 2, Issue:3

    Topics: Abietanes; Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line; Digoxin; Dogs; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Multidrug Resistance-Associated Proteins; Phenanthrenes; Plant Roots; Salvia miltiorrhiza; Temperature

2008
Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Sep-25, Volume: 21, Issue:11

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Camptothecin; Digoxin; Doxorubicin; Drugs, Chinese Herbal; Furans; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Phenanthrenes; Quinones; Salvia miltiorrhiza

2014