Page last updated: 2024-09-02

tanshinone and curcumin

tanshinone has been researched along with curcumin in 8 studies

Compound Research Comparison

Studies
(tanshinone)
Trials
(tanshinone)
Recent Studies (post-2010)
(tanshinone)
Studies
(curcumin)
Trials
(curcumin)
Recent Studies (post-2010) (curcumin)
1,445101,03316,33659312,705

Protein Interaction Comparison

ProteinTaxonomytanshinone (IC50)curcumin (IC50)
toll-like receptor 9Homo sapiens (human)8.362
TPA: protein transporter TIM10Saccharomyces cerevisiae S288C19.7
intestinal alkaline phosphatase precursorMus musculus (house mouse)18.7
perilipin-1Homo sapiens (human)9.167
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)9.167
hypothetical protein SA1422Staphylococcus aureus subsp. aureus N31542.9
Prostaglandin E synthaseHomo sapiens (human)1.8
Lysine-specific histone demethylase 1AHomo sapiens (human)9.6
D-amino-acid oxidaseSus scrofa (pig)1.07
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)3
Amyloid-beta precursor proteinHomo sapiens (human)4.3079
Neuronal proto-oncogene tyrosine-protein kinase Src Mus musculus (house mouse)2.2
Heme oxygenase 1 Rattus norvegicus (Norway rat)10
Microtubule-associated protein tauHomo sapiens (human)3.25
60 kDa heat shock protein, mitochondrialHomo sapiens (human)8.3
Tissue factorHomo sapiens (human)0.0132
TyrosinaseHomo sapiens (human)5
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2Homo sapiens (human)7
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.066
Amine oxidase [flavin-containing] AHomo sapiens (human)3.5
Heme oxygenase 2Rattus norvegicus (Norway rat)10
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)5.4
Amine oxidase [flavin-containing] BHomo sapiens (human)2.5733
Proteasome subunit beta type-5Homo sapiens (human)10
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)1.73
Alpha-synucleinHomo sapiens (human)0.22
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.4
10 kDa heat shock protein, mitochondrialHomo sapiens (human)8.3
Histone acetyltransferase p300Homo sapiens (human)6.5
60 kDa chaperonin Escherichia coli3
10 kDa chaperonin Escherichia coli3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3Homo sapiens (human)7
Cysteine protease Trypanosoma brucei rhodesiense7.75
CDGSH iron-sulfur domain-containing protein 1Homo sapiens (human)2.36
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.63
Beta lactamase (plasmid)Pseudomonas aeruginosa7.751

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (87.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Bentley, JN; Dhandapani, KM; Laird, MD; Singh, N; Sukumari-Ramesh, S; Vender, JR1
Gong, YP; Guo, Y; Lin, J; Shan, QQ; Yang, X; Zhou, RQ1
Chen, CY; Li, WC; Ting, CT; Tsai, TH1
Jiang, S; Li, K; Sun, X; Wang, M; Wang, Q; Wang, S; Zhang, C; Zhu, R1
Gong, H; Huang, K; Ji, K; Liu, Y; Wang, Z; Yang, X; Yu, T; Zhao, Y1
Li, H; Liu, JG; Wang, ZY; Yang, HM1
Anuchapreeda, S; Chiampanichayakul, S; Krig, SR; Rungrojsakul, M; Tima, S1

Reviews

2 review(s) available for tanshinone and curcumin

ArticleYear
Preventive and therapeutic role of traditional Chinese herbal medicine in hepatocellular carcinoma.
    Journal of the Chinese Medical Association : JCMA, 2015, Volume: 78, Issue:3

    Topics: Abietanes; Benzylisoquinolines; Berberine; Carcinoma, Hepatocellular; Curcumin; Drugs, Chinese Herbal; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Resveratrol; Scutellaria baicalensis; Stilbenes

2015
Pharmacological Effects of Active Components of Chinese Herbal Medicine in the Treatment of Alzheimer's Disease: A Review.
    The American journal of Chinese medicine, 2016, Volume: 44, Issue:8

    Topics: Abietanes; Alkaloids; Alzheimer Disease; Curcuma; Curcumin; Drugs, Chinese Herbal; Epimedium; Evodia; Flavonoids; Ginsenosides; Humans; Huperzia; Panax; Phytotherapy; Plant Extracts; Quinazolines; Salvia miltiorrhiza; Scutellaria baicalensis; Sesquiterpenes

2016

Other Studies

6 other study(ies) available for tanshinone and curcumin

ArticleYear
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021
Dietary phytochemicals induce p53- and caspase-independent cell death in human neuroblastoma cells.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:7

    Topics: Abietanes; Anti-Inflammatory Agents; Antineoplastic Agents; bcl-X Protein; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Chalcones; Chromones; Coumarins; Curcumin; Diet; Diterpenes; Humans; Morpholines; Neuroblastoma; NF-kappa B; Plant Extracts; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53

2011
[Anti-tumor effect of tanshinone II A, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2012, Volume: 43, Issue:3

    Topics: Abietanes; Acetophenones; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Curcumin; Diterpenes, Kaurane; Drugs, Chinese Herbal; HL-60 Cells; Humans; K562 Cells; Leukemia; Lignans; Plants, Medicinal

2012
The triplet state of tanshinone I and its synergic effect on the phototherapy of cancer cells with curcumin.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Volume: 150

    Topics: Abietanes; Antineoplastic Agents; Curcumin; Drug Synergism; Drugs, Chinese Herbal; Energy Transfer; Humans; Lasers; Molecular Structure; Neoplasms; Photolysis; Phototherapy; Salvia miltiorrhiza; Tumor Cells, Cultured

2015
Inhibition effects of tanshinone on the aggregation of α-synuclein.
    Food & function, 2016, Volume: 7, Issue:1

    Topics: Abietanes; alpha-Synuclein; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Curcumin; Escherichia coli; Humans; Molecular Structure; Parkinson Disease; Protein Folding

2016
Co-activation of WT1 and AP-1 proteins on WT1 gene promoter to induce WT1 gene expression in K562 cells.
    Cellular signalling, 2019, Volume: 53

    Topics: Abietanes; Anthracenes; Antineoplastic Agents; Curcumin; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia; Promoter Regions, Genetic; Protein Kinase Inhibitors; Transcription Factor AP-1; WT1 Proteins

2019