tanshinone has been researched along with cardiovascular agents in 15 studies
| Studies (tanshinone) | Trials (tanshinone) | Recent Studies (post-2010) (tanshinone) | Studies (cardiovascular agents) | Trials (cardiovascular agents) | Recent Studies (post-2010) (cardiovascular agents) |
|---|---|---|---|---|---|
| 1,445 | 10 | 1,033 | 17,645 | 1,480 | 6,891 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Fujimoto, K; Hirai, K; Kawaguchi, K; Ogawa, M; Takeo, S; Tanonaka, K; Yagi, A | 1 |
| Bai, DL; Sun, CJ | 1 |
| Bi, HC; Chen, X; Gu, LQ; Huang, M; Huang, ZY; Liu, PQ; Pan, Y; Zhao, LZ; Zhong, GP; Zhou, SF; Zuo, Z | 1 |
| Cao, L; Mao, C; Shao, H; Wang, L; Xu, Z; Zhang, Y; Zhu, L | 1 |
| Bai, H; Dong, CD; Gu, X; Liu, JP; Yang, RH; Zhang, WL | 1 |
| Chen, JW; Fang, J; Gao, J; Huang, HQ; Liu, PQ; Tang, FT; Wang, P; Xu, SW; Zhou, SG | 1 |
| Chen, M; Huo, Y; Li, J; Lou, L; Pan, C; Singh, G; Wang, S; Wu, A; Zhang, D; Zhao, M | 1 |
| Fan, G; Gao, X; Hu, L; Jiang, M; Li, X; Wang, X; Wang, Y; Zhu, Y | 1 |
| Gao, S; Li, H; Little, PJ; Liu, P; Liu, Z; Xu, S | 1 |
| Fan, YQ; Li, J; Liu, JP; Liu, P; Yang, JK; Zhang, WL | 1 |
| Li, J; Liu, J; Wang, J; Wu, Z; Xu, Y; Zhang, W | 1 |
| Cui, L; Hao, X; Huang, Q; Ju, G; Kai, G; Luo, X; Shi, M; Xiao, J; Yu, X | 1 |
| Li, J; Li, ZH; Liu, JP; Yan, HX; Zhang, WL | 1 |
| Chen, HW; Feng, J; Pi, LJ; Wang, J; Zhan, DQ | 1 |
| Wang, X; Wu, C | 1 |
1 review(s) available for tanshinone and cardiovascular agents
| Article | Year |
|---|---|
Cardiovascular actions and therapeutic potential of tanshinone IIA.
Topics: Abietanes; Animals; Cardiovascular Agents; Cardiovascular Diseases; Humans; Treatment Outcome | 2012 |
14 other study(ies) available for tanshinone and cardiovascular agents
| Article | Year |
|---|---|
Beneficial effect of tan-shen, an extract from the root of Salvia, on post-hypoxic recovery of cardiac contractile force.
Topics: Abietanes; Adenosine Triphosphate; Animals; Calcium; Cardiovascular Agents; Creatine Kinase; Hypoxia; Male; Myocardial Contraction; Myocardial Reperfusion; Phenanthrenes; Phosphates; Rats; Rats, Inbred Strains | 1990 |
[Synthesis of some compounds related to tanshinquinone].
Topics: Abietanes; Anti-Bacterial Agents; Cardiovascular Agents; Diterpenes; Drug Resistance, Microbial; Phenanthrenes; Quinones; Staphylococcus aureus | 1985 |
Pharmacokinetic characterization of hydroxylpropyl-beta-cyclodextrin-included complex of cryptotanshinone, an investigational cardiovascular drug purified from Danshen (Salvia miltiorrhiza).
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Abietanes; Administration, Oral; Animals; beta-Cyclodextrins; Cardiovascular Agents; Dogs; Drugs, Chinese Herbal; Drugs, Investigational; Female; Male; Phenanthrenes; Phenanthrolines; Rats; Salvia miltiorrhiza; Tissue Distribution | 2008 |
The effect of tanshinone IIA on the cardiovascular system in ovine fetus in utero.
Topics: Abietanes; Animals; Blood Pressure; Cardiovascular Agents; Drugs, Chinese Herbal; Female; Fetal Heart; Fetus; Hematology; Models, Animal; Myocardium; Oxygen; Phenanthrenes; Pregnancy; Pregnancy Trimester, Third; Salvia miltiorrhiza; Sheep; Uterus | 2009 |
Nanostructured lipid carriers constituted from high-density lipoprotein components for delivery of a lipophilic cardiovascular drug.
Topics: Abietanes; Cardiovascular Agents; Cell Line; Cell Survival; Drug Carriers; Drug Compounding; Lipoproteins, HDL; Nanoparticles; Particle Size; Phagocytosis; Phenanthrenes; Surface Properties | 2010 |
Tanshinone II-A attenuates cardiac fibrosis and modulates collagen metabolism in rats with renovascular hypertension.
Topics: Abietanes; Animals; Blood Pressure; Cardiovascular Agents; Collagen; Drugs, Chinese Herbal; Fibrosis; Gene Expression; Heart; Hypertension, Renovascular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Phytotherapy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Salvia miltiorrhiza; Tetrazoles; Tissue Inhibitor of Metalloproteinase-1; Valine; Valsartan | 2010 |
Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways.
Topics: Abietanes; Amino Acid Transport Systems, Basic; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Arginine; Benzofurans; Cardiovascular Agents; Cationic Amino Acid Transporter 1; Cells, Cultured; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Time Factors; Vasodilation | 2011 |
Differential cardioprotective effects of salvianolic acid and tanshinone on acute myocardial infarction are mediated by unique signaling pathways.
Topics: Abietanes; Animals; Apoptosis; Caffeic Acids; Calcium; Cardiovascular Agents; Cell Adhesion; Complement Pathway, Alternative; Disease Models, Animal; Drugs, Chinese Herbal; Estrogens; Gene Expression Regulation; Heart; Lactates; Male; Microarray Analysis; Myocardial Infarction; Oxidative Stress; Phenanthrolines; Phytotherapy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Salvia miltiorrhiza; Selective Estrogen Receptor Modulators; Signal Transduction; Systole | 2011 |
Novel Tanshinone II A ternary solid dispersion pellets prepared by a single-step technique: in vitro and in vivo evaluation.
Topics: Abietanes; Administration, Oral; Animals; Area Under Curve; Biological Availability; Calorimetry, Differential Scanning; Cardiovascular Agents; Drug Carriers; Male; Poloxamer; Povidone; Rabbits; Solubility; Time Factors | 2012 |
Tanshinone IIA-loaded reconstituted high density lipoproteins: Atherosclerotic plaque targeting mechanism in a foam cell model and pharmacokinetics in rabbits.
Topics: Abietanes; Animals; Apolipoproteins; Cardiovascular Agents; Cell Line; Circular Dichroism; Drug Carriers; Drug Delivery Systems; Electrochemistry; Foam Cells; In Vitro Techniques; Infusions, Parenteral; Lipoproteins, HDL; Liposomes; Male; Mice; Models, Biological; Nanoparticles; Particle Size; Phagocytosis; Plaque, Atherosclerotic; Plasmids; Rabbits; Reproducibility of Results; Transfection | 2012 |
Increased accumulation of the cardio-cerebrovascular disease treatment drug tanshinone in Salvia miltiorrhiza hairy roots by the enzymes 3-hydroxy-3-methylglutaryl CoA reductase and 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Topics: Abietanes; Aldose-Ketose Isomerases; Biphenyl Compounds; Cardiovascular Agents; Free Radical Scavengers; Gene Expression; Hydroxymethylglutaryl CoA Reductases; Oxidation-Reduction; Picrates; Plant Proteins; Plant Roots; Plants, Genetically Modified; Salvia miltiorrhiza | 2014 |
Tanshinone IIA - loaded pellets developed for angina chronotherapy: Deconvolution-based formulation design and optimization, pharmacokinetic and pharmacodynamic evaluation.
Topics: Abietanes; Administration, Oral; Angina Pectoris; Animals; Cardiovascular Agents; Chemistry, Pharmaceutical; Computer Simulation; Delayed-Action Preparations; Disease Models, Animal; Drug Chronotherapy; Excipients; Male; Models, Biological; Nitric Oxide; Polyethylene Glycols; Polyvinyl Alcohol; Polyvinyls; Rabbits; Solubility; Technology, Pharmaceutical | 2015 |
Protective effect of tanshinone IIA against cardiac hypertrophy in spontaneously hypertensive rats through inhibiting the Cys-C/Wnt signaling pathway.
Topics: Abietanes; Animals; Arginine; Cardiomegaly; Cardiovascular Agents; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Cystatin C; Disease Models, Animal; Hypertension; Male; Myocardium; NADPH Oxidase 4; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Troponin I; Wnt Signaling Pathway | 2017 |
Tanshinone IIA improves cardiac function via regulating miR-499-5p dependent angiogenesis in myocardial ischemic mice.
Topics: Abietanes; Animals; Cardiovascular Agents; Disease Models, Animal; Mice; Mice, Inbred C57BL; MicroRNAs; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Neovascularization, Pathologic; Neovascularization, Physiologic; PTEN Phosphohydrolase | 2022 |