Page last updated: 2024-09-02

tanshinone and camptothecin

tanshinone has been researched along with camptothecin in 3 studies

Compound Research Comparison

Studies
(tanshinone)
Trials
(tanshinone)
Recent Studies (post-2010)
(tanshinone)
Studies
(camptothecin)
Trials
(camptothecin)
Recent Studies (post-2010) (camptothecin)
1,445101,03313,0022,2295,391

Protein Interaction Comparison

ProteinTaxonomytanshinone (IC50)camptothecin (IC50)
Histone deacetylase 3Homo sapiens (human)0.05
Multidrug resistance-associated protein 4Homo sapiens (human)7.4
DNA topoisomerase 1Homo sapiens (human)1.9799
Somatostatin receptor type 1Homo sapiens (human)0.0022
Somatostatin receptor type 2Homo sapiens (human)0.0022
Somatostatin receptor type 4Homo sapiens (human)0.0022
Somatostatin receptor type 3Homo sapiens (human)0.0022
Somatostatin receptor type 5Homo sapiens (human)0.0022
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.97
Histone deacetylase 4Homo sapiens (human)0.05
Histone deacetylase 1Homo sapiens (human)0.05
Histone deacetylase 7Homo sapiens (human)0.05
Histone deacetylase 2Homo sapiens (human)0.05
Polyamine deacetylase HDAC10Homo sapiens (human)0.05
Histone deacetylase 11 Homo sapiens (human)0.05
Histone deacetylase 8Homo sapiens (human)0.05
Histone deacetylase 6Homo sapiens (human)0.05
Histone deacetylase 9Homo sapiens (human)0.05
Histone deacetylase 5Homo sapiens (human)0.05

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, M; Fronza, M; Hamburger, M; Heinzmann, B; Laufer, S; Merfort, I; Murillo, R; ƚlusarczyk, S1
Edwards, CC; Hatfield, MJ; Hyatt, JL; Jeffries, C; Lemoff, A; Potter, PM; Tsurkan, LG; Yan, B1
Chan, RL; Cho, CH; Hu, T; Li, M; Lu, L; Shen, J; To, KK; Wang, L; Yeung, JH; Zhang, L1

Other Studies

3 other study(ies) available for tanshinone and camptothecin

ArticleYear
In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica.
    Bioorganic & medicinal chemistry, 2011, Aug-15, Volume: 19, Issue:16

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cytotoxins; Drug Screening Assays, Antitumor; Humans; Lamiaceae; Phytotherapy; Plant Extracts; Plant Roots; Salvia; Structure-Activity Relationship

2011
Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").
    Journal of natural products, 2013, Jan-25, Volume: 76, Issue:1

    Topics: Abietanes; Algorithms; Camptothecin; Carboxylesterase; Clinical Trials, Phase I as Topic; Drugs, Chinese Herbal; Herb-Drug Interactions; Humans; Irinotecan; Medicine, Chinese Traditional; Molecular Structure; Phenanthrolines; Plant Roots; Salvia miltiorrhiza

2013
Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Sep-25, Volume: 21, Issue:11

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Camptothecin; Digoxin; Doxorubicin; Drugs, Chinese Herbal; Furans; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Phenanthrenes; Quinones; Salvia miltiorrhiza

2014