Page last updated: 2024-09-02

tanshinone and benzofurans

tanshinone has been researched along with benzofurans in 54 studies

Compound Research Comparison

Studies
(tanshinone)
Trials
(tanshinone)
Recent Studies (post-2010)
(tanshinone)
Studies
(benzofurans)
Trials
(benzofurans)
Recent Studies (post-2010) (benzofurans)
1,445101,03313,2934514,970

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (27.78)29.6817
2010's33 (61.11)24.3611
2020's6 (11.11)2.80

Authors

AuthorsStudies
Chen, YJ; Kuo, YH; Liao, HF; Shyu, SY; Yang, YC1
Chen, LN; Zhu, XX1
Chow, MS; Zhou, L; Zuo, Z1
Guo, ZX; Shi, CX; Yang, YW; Zhu, GG1
Liu, YR; Maitz, MF; Qu, SX; Tan, R; Weng, J1
Hang, TJ; Song, M; Zhang, ZX1
Chou, GX; Hu, ZB; Li, YG; Liu, M; Wang, ZT; Yang, L; Zhang, F1
Chen, Q; Deng, L; Fu, H; Gong, T; Liu, J; Nie, Y; Wang, X; Zhang, ZR1
Chen, X; Tang, XQ; Wang, KC; Yu, BY1
Cai, SS; Dong, HP; Wang, N; Wei, H1
Deng, M; Yang, H; Yi, H1
Guo, L; Lei, CK; Shan, M1
Li, CG; Marriott, P; May, B; Pang, EC; Sheng, SJ; Story, D; Xue, CC; Zhou, S1
Li, CG; Pang, EC; Sheng, SJ; Xue, CC1
Li, CG; May, B; Pang, EC; Sheng, SJ; Xue, CC2
Liang, X; Liu, X; Lu, Y; Xiang, L; Zhang, W1
Chen, M; Huo, Y; Li, J; Lou, L; Pan, C; Singh, G; Wang, S; Wu, A; Zhang, D; Zhao, M1
Guo, L; Huang, L; Jin, H; Liu, D; Wu, L; Yang, Y; Zeng, Y; Zhang, J1
Chen, L; Li, W; Xu, L; Zhou, Y1
Chen, XD; Feng, ZS; Lan, J; Li, XE1
Kwan, YW; Lee, WY; Or, PM; Yeung, JH; Zhou, X1
Li, XB; Li, Y; Wang, W; Xie, XM; Zhou, GJ; Zhou, TS1
Chen, JF; Chen, WS; Di, P; Gu, XC; Xiao, Y; Xuan, HJ; Zhang, L; Zhou, X1
Chen, G; Li, X; Long, W; Mu, L; Shao, AL; Wen, L; Yang, F; Zhang, X1
Du, MB; Hou, R; Liang, RX; Liu, SZ; Wang, L; Wang, YL; Zhang, JY1
Ding, C; Jiang, Y; Wang, L; Wang, T; Wang, X; Yang, R; Zhang, H; Zhang, L; Zhou, Y1
Achenbach, S; Daniel, WG; Fan, Q; Garlichs, CD; Hintermann, C; Kurfürst, I; Losert, S; Pflederer, W; Raaz, D; Stumpf, C1
Han, T; Jia, M; Ming, Q; Qin, L; Rahman, K; Su, C; Zhang, H; Zhang, Q; Zheng, C1
Cao, W; Dai, J; Guan, H; He, L; Lin, J; Wang, X; Wang, Y; Wu, Q1
Cheung, WM; Ho, WS; Kan, S; Zhou, Y1
Chen, M; Chen, ML; Li, PY; Li, XM; Wang, X; Yang, G1
Liu, SM; Sun, XB; Yang, ZH1
Li, B; Liang, Z; Peng, L; Ru, M; Wang, K; Wang, Y; Xia, P1
Chen, G; Long, W; Mu, L; Wen, L; Yang, F; Zhang, SC1
Chen, XX; Dai, JP; Li, KS; Li, WZ; Sheng, JT; Su, Y; Wang, GF; Zhu, DX1
Mao, S; Wei, G; Xiuli, W1
Duan, J; Guan, H; Qian, D; Ren, H; Shang, E; Su, S; Zhang, W1
Chen, WD; Peng, DY; Peng, HS; Shi, SM; Yu, F; Yu, NJ1
Geng, YL; Li, FS; Liu, JH; Liu, W; Sun, P; Wang, X; Wei, YY; Zhou, J1
Wang, R; Wang, Y; Yu, X; Yuan, Y; Zhang, H1
Huang, PH; Li, JP; Liu, SK; Liu, SL; Pei, Q; Tang, Z; Wang, H; Yang, GP; Zhang, J1
Bai, J; Chen, XN; Du, SY; Lu, Y; Tian, ZH; Wan, J; Wang, M; Wu, HC; Zhang, QS1
Gao, H; Huang, H; Li, N; Yu, N; Zheng, A1
Jin, S; Li, G; Wang, XL1
Chang, WT; Chen, IJ; Ko, CY; Lee, MS; Lin, MK1
Dou, HT; Fu, XX; Hua, JH; Pan, YL; Wang, JH; Zhao, Q1
Jiang, C; Liu, J; Tang, H; Wang, B; Wang, D; Zhang, S1
Cao, F; Gao, J; Hu, B; Li, B; Li, J; Luo, L; Peng, L; Yan, Y; Yang, B; Zhang, G1
Li, SP; Liu, MT; Zhao, J1
Cao, SD; Gao, CX; Guo, Y; He, Y; Jin, B; Wan, HT; Wang, Y; Yang, JH1
Jia, LJ; Li, JP; Liu, SL; Shi, LY; Wang, H; Xie, BP; Zhang, J1
Bednarikova, Z; Gancar, M; Gazova, Z; Huang, Y; Luo, Y; Ma, L; Spodniakova, B; Tang, Y; Wang, R; Zheng, L1
Gu, H; Lin, T; Wang, XJ; Wang, XL; Zhang, XR1

Reviews

2 review(s) available for tanshinone and benzofurans

ArticleYear
[Advances in study of the pharmacological effects of danshen on hemorheology].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:8

    Topics: Abietanes; Animals; Benzofurans; Drugs, Chinese Herbal; Hemorheology; Hemostasis; Lactates; Phenanthrenes; Plant Roots; Plants, Medicinal; Platelet Aggregation; Salvia miltiorrhiza

2005
Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:12

    Topics: Abietanes; Angina Pectoris; Animals; Benzofurans; Drugs, Chinese Herbal; Fibrinolytic Agents; Herb-Drug Interactions; Humans; Hyperlipidemias; Lactates; Phenanthrenes; Phenanthrolines; Plant Extracts; Randomized Controlled Trials as Topic; Salvia miltiorrhiza; Stroke

2005

Other Studies

52 other study(ies) available for tanshinone and benzofurans

ArticleYear
Compound 278E, structurally modified from tanshinone, induces monocytic differentiation and regulates proto-oncogene expression in human leukemic HL-60 cells.
    Anti-cancer drugs, 2005, Volume: 16, Issue:2

    Topics: Abietanes; Antineoplastic Agents; Benzofurans; Cell Differentiation; Cell Proliferation; Drugs, Chinese Herbal; Esterases; HL-60 Cells; Humans; Isoenzymes; Monocytes; Phenanthrenes; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins; Salvia miltiorrhiza; Superoxides

2005
[Quantitative analysis on Radix Salviae miltiorrhizae by NIR].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:9

    Topics: Abietanes; Benzofurans; Electronic Data Processing; Least-Squares Analysis; Models, Theoretical; Phenanthrenes; Plant Roots; Plants, Medicinal; Quality Control; Reproducibility of Results; Salvia miltiorrhiza; Spectroscopy, Near-Infrared

2006
The effect of the major components of Salvia Miltiorrhiza Bunge on bone marrow cells.
    Journal of ethnopharmacology, 2007, May-22, Volume: 111, Issue:3

    Topics: Abietanes; Alkaline Phosphatase; Animals; Benzaldehydes; Benzofurans; Bone Marrow Cells; Catechols; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Male; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Phenanthrenes; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza

2007
[Pharmacokinetic interactions between the main components in the extracts of Salvia miltiorrhiza Bge. in rat].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:3

    Topics: Abietanes; Animals; Area Under Curve; Benzaldehydes; Benzofurans; Catechols; Drug Interactions; Female; Male; Metabolic Clearance Rate; Molecular Structure; Phenanthrenes; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza

2007
Chromatographic fingerprinting analysis of Danshen root (Salvia miltiorrhiza Radix et Rhizoma) and its preparations using high performance liquid chromatography with diode array detection and electrospray mass spectrometry (HPLC-DAD-ESI/MS).
    Journal of separation science, 2007, Volume: 30, Issue:14

    Topics: Abietanes; Benzofurans; Caffeic Acids; Chromatography, High Pressure Liquid; Cinnamates; Diterpenes; Drugs, Chinese Herbal; Lactates; Molecular Structure; Phenanthrenes; Phenylpropionates; Plant Extracts; Plant Roots; Reference Standards; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization

2007
Simultaneous determination and pharmacokinetic study of water-soluble and lipid-soluble components of danshen in rat plasma using HPLC-UV method.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:11

    Topics: Abietanes; Animals; Benzofurans; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hydrophobic and Hydrophilic Interactions; Lipids; Molecular Structure; Phenanthrenes; Phenanthrolines; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Salvia miltiorrhiza; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Water

2007
[Analysis on biomasses and contents of active components in roots of Salvia miltiorrhiza from different populations].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:23

    Topics: Abietanes; Benzofurans; Biomass; Caffeic Acids; China; Chromatography, High Pressure Liquid; Ecosystem; Lactates; Phenanthrenes; Plant Roots; Plants, Medicinal; Salvia miltiorrhiza; Spectrophotometry, Ultraviolet

2007
[A new method for quick analysis of tanshinone II(A) and salvianolic acid in Fufang Danshen tablets by AOTF-near infrared spectroscopy].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:3

    Topics: Abietanes; Benzofurans; Drugs, Chinese Herbal; Phenanthrenes; Reproducibility of Results; Spectroscopy, Near-Infrared; Tablets

2008
[Experiment of extracting Salviae miltiorrhizae on using O/W microemulsion].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:22

    Topics: Abietanes; Benzofurans; Drugs, Chinese Herbal; Emulsions; Oils; Phenanthrenes; Reproducibility of Results; Salvia miltiorrhiza; Water

2008
[Study of growth inhibitory effect and apoptosis induced by different matches of Tanshinone IIA and Salvianolic Acid B on Acute Promyelocytic Leukemia cells (HL-60)].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:10

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Benzofurans; Cell Proliferation; Drugs, Chinese Herbal; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Phenanthrenes; Plants, Medicinal; Salvia miltiorrhiza

2008
Cultivar variations of Australian-grown Danshen (Salvia miltiorrhiza): bioactive markers and root yields.
    Chemistry & biodiversity, 2009, Volume: 6, Issue:2

    Topics: Abietanes; Australia; Benzofurans; Chromatography, High Pressure Liquid; Medicine, Chinese Traditional; Phenanthrenes; Plant Roots; Salvia miltiorrhiza

2009
Seasonal variations in bioactive marker contents in Australian-grown Salvia miltiorrhiza roots.
    Chemistry & biodiversity, 2009, Volume: 6, Issue:4

    Topics: Abietanes; Australia; Benzofurans; Biomarkers; Chromatography, High Pressure Liquid; Phenanthrenes; Plant Roots; Salvia miltiorrhiza; Seasons

2009
HPLC profiles and biomarker contents of Australian-grown Salvia miltiorrhiza f. alba roots.
    Chemistry & biodiversity, 2009, Volume: 6, Issue:7

    Topics: Abietanes; Australia; Benzofurans; Biomarkers; Chromatography, High Pressure Liquid; Phenanthrenes; Plant Roots; Plants, Medicinal; Salvia miltiorrhiza

2009
Metabolomic strategy to study therapeutic and synergistic effects of tanshinone IIA, salvianolic acid B and ginsenoside Rb1 in myocardial ischemia rats.
    Journal of ethnopharmacology, 2011, Mar-08, Volume: 134, Issue:1

    Topics: Abietanes; Animals; Benzofurans; Chromatography, Liquid; Ginsenosides; Male; Mass Spectrometry; Metabolomics; Rats; Rats, Sprague-Dawley

2011
Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways.
    Therapeutic advances in cardiovascular disease, 2011, Volume: 5, Issue:2

    Topics: Abietanes; Amino Acid Transport Systems, Basic; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Arginine; Benzofurans; Cardiovascular Agents; Cationic Amino Acid Transporter 1; Cells, Cultured; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Time Factors; Vasodilation

2011
Plant density-dependent variations in bioactive markers and root yield in Australian-grown Salvia miltiorrhiza Bunge.
    Chemistry & biodiversity, 2011, Volume: 8, Issue:4

    Topics: Abietanes; Australia; Benzofurans; Phenanthrenes; Plant Roots; Salvia miltiorrhiza

2011
[Effects of soil water content on seedlings growth and active ingredients of Salvia miltiorrhiza].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:3

    Topics: Abietanes; Benzofurans; Biomass; Minerals; Plant Roots; Salvia miltiorrhiza; Seedlings; Soil; Stress, Physiological; Water

2011
In Salvia miltiorrhiza, phenolic acids possess protective properties against amyloid β-induced cytotoxicity, and tanshinones act as acetylcholinesterase inhibitors.
    Environmental toxicology and pharmacology, 2011, Volume: 31, Issue:3

    Topics: Abietanes; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Benzofurans; Calcium; Cell Survival; Cholinesterase Inhibitors; Hydroxybenzoates; L-Lactate Dehydrogenase; Male; Neuroprotective Agents; PC12 Cells; Phosphatidylinositols; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Tetrazolium Salts; Thiazoles

2011
[The quality of Salvia miltforthiza from Beijing suburbs with different growing modes].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:1

    Topics: Abietanes; Agriculture; Benzofurans; Biomass; China; Malus; Metals, Heavy; Pesticide Residues; Plants, Medicinal; Quality Control; Salvia; Soil; Trees

2011
Tanshinone I increases CYP1A2 protein expression and enzyme activity in primary rat hepatocytes.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Jan-15, Volume: 19, Issue:2

    Topics: Abietanes; Animals; Benzofurans; Cell Survival; Cytochrome P-450 CYP1A2; Cytochromes; Drugs, Chinese Herbal; Enzyme Activation; Enzyme Induction; Ethanol; Hepatocytes; Male; Phenacetin; Phenanthrenes; Phenanthrolines; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA, Messenger; Salvia miltiorrhiza; Tacrine

2012
Production of salvianolic acid B in roots of Salvia miltiorrhiza (Danshen) during the post-harvest drying process.
    Molecules (Basel, Switzerland), 2012, Feb-27, Volume: 17, Issue:3

    Topics: Abietanes; Benzofurans; Chromatography, High Pressure Liquid; Desiccation; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Phenanthrenes; Plant Roots; Salvia miltiorrhiza

2012
Overexpression of allene oxide cyclase promoted tanshinone/phenolic acid production in Salvia miltiorrhiza.
    Plant cell reports, 2012, Volume: 31, Issue:12

    Topics: Abietanes; Acetates; Benzofurans; Cinnamates; Cloning, Molecular; Cold Temperature; Cyclopentanes; Depsides; Diterpenes; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Genetic Engineering; Genetic Vectors; Hydroxybenzoates; Intramolecular Oxidoreductases; Oxylipins; Plant Roots; Rosmarinic Acid; Salvia miltiorrhiza; Transgenes; Ultraviolet Rays

2012
Novel multiple agents loaded PLGA nanoparticles for brain delivery via inner ear administration: in vitro and in vivo evaluation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Mar-12, Volume: 48, Issue:4-5

    Topics: Abietanes; Animals; Benzofurans; Brain; Carotid Arteries; Drug Administration Routes; Drug Carriers; Ear, Inner; Ginsenosides; Guinea Pigs; Lactic Acid; Male; Nanoparticles; Neuroprotective Agents; Panax notoginseng; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Reperfusion Injury

2013
[Pharmacokinetic study on three main ingredients of refined coronary cataplasm].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:23

    Topics: Abietanes; Animals; Benzoates; Benzofurans; Bridged-Ring Compounds; Chromatography, Liquid; Coronary Disease; Drugs, Chinese Herbal; Glucosides; Humans; Male; Monoterpenes; Rabbits; Tandem Mass Spectrometry

2012
A simple and reliable method for distinguishing danshen in salvia: simultaneous quantification of six active compositions by HPLC.
    Journal of chromatographic science, 2014, Volume: 52, Issue:9

    Topics: Abietanes; Benzofurans; Caffeic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lactates; Limit of Detection; Phenanthrenes; Reproducibility of Results; Salvia; Salvia miltiorrhiza

2014
Anti-inflammatory effects of danshen on human vascular endothelial cells in culture.
    The American journal of Chinese medicine, 2013, Volume: 41, Issue:5

    Topics: Abietanes; Adenosine Diphosphate; Anti-Inflammatory Agents; Atherosclerosis; Benzofurans; Blood Platelets; CD40 Antigens; Cells, Cultured; Chemokine CCL2; Down-Regulation; Drugs, Chinese Herbal; Human Umbilical Vein Endothelial Cells; Humans; Hydroxybenzoates; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; P-Selectin; Salvia miltiorrhiza; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2013
Elicitors from the endophytic fungus Trichoderma atroviride promote Salvia miltiorrhiza hairy root growth and tanshinone biosynthesis.
    Journal of experimental botany, 2013, Volume: 64, Issue:18

    Topics: Abietanes; Benzofurans; Biomass; Cinnamates; Depsides; Endophytes; Gene Expression Regulation, Plant; Mycelium; Phenols; Plant Roots; Polysaccharides; Rosmarinic Acid; Salvia miltiorrhiza; Trichoderma

2013
Development of Salvianolic acid B-Tanshinone II A-Glycyrrhetinic acid compound liposomes: formulation optimization and its effects on proliferation of hepatic stellate cells.
    International journal of pharmaceutics, 2014, Feb-28, Volume: 462, Issue:1-2

    Topics: Abietanes; Benzofurans; Cell Line; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Delayed-Action Preparations; Glycyrrhetinic Acid; Hepatic Stellate Cells; Humans; Hydrophobic and Hydrophilic Interactions; Liposomes; Microscopy, Electron, Transmission; Particle Size; Time Factors

2014
Enhancement of doxorubicin cytotoxicity by tanshinone IIA in HepG2 human hepatoma cells.
    Planta medica, 2014, Volume: 80, Issue:1

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Benzofurans; Caspase 3; Chlorogenic Acid; Doxorubicin; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species

2014
[Effect of Glomus versiforme and Trichoderma harzianum on growth and quality of Salvia miltiorrhiza].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:9

    Topics: Abietanes; Antibiosis; Benzofurans; Glomeromycota; Host-Pathogen Interactions; Phenanthrenes; Plant Diseases; Plant Roots; Salvia miltiorrhiza; Trichoderma

2014
[Simultaneous determination of six Salvia miltiorrhiza gradients in rat plasma and brain by LC-MS/MS].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:9

    Topics: Abietanes; Animals; Benzaldehydes; Benzofurans; Blood-Brain Barrier; Brain; Caffeic Acids; Catechols; Chromatography, Liquid; Hydroxybenzoates; Injections, Intravenous; Lactates; Phenanthrenes; Plant Preparations; Rats; Reproducibility of Results; Salvia miltiorrhiza; Tandem Mass Spectrometry

2014
Spaceflight environment-induced variation in root yield and active constituents of Salvia miltiorrhiza.
    Planta medica, 2014, Volume: 80, Issue:12

    Topics: Abietanes; Benzofurans; Biomass; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Environment; Humans; Phenanthrenes; Plant Extracts; Plant Roots; Principal Component Analysis; Rosmarinic Acid; Salvia miltiorrhiza; Space Flight

2014
In vivo distribution and pharmacokinetics of multiple active components from Danshen and Sanqi and their combination via inner ear administration.
    Journal of ethnopharmacology, 2014, Oct-28, Volume: 156

    Topics: Abietanes; Animals; Benzofurans; Cerebrospinal Fluid; Drugs, Chinese Herbal; Ear, Inner; Ginsenosides; Guinea Pigs; Herb-Drug Interactions; Medicine, Chinese Traditional; Panax notoginseng; Salvia miltiorrhiza

2014
Inhibition of Tanshinone IIA, salvianolic acid A and salvianolic acid B on Areca nut extract-induced oral submucous fibrosis in vitro.
    Molecules (Basel, Switzerland), 2015, Apr-15, Volume: 20, Issue:4

    Topics: Abietanes; Animals; Areca; Benzofurans; Caffeic Acids; Cell Line; Cell Survival; Collagen; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; Humans; In Vitro Techniques; Lactates; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Nuts; Oral Submucous Fibrosis; Plant Exudates; Proto-Oncogene Proteins c-akt; Signal Transduction; Smad Proteins; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta

2015
Pharmacokinetic investigation on interaction between hydrophilic lithospermic acid B and lipophilic tanshinone IIA in rats: an experi- mental study.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2015, Volume: 35, Issue:2

    Topics: Abietanes; Animals; Benzofurans; Chromatography, High Pressure Liquid; Depsides; Drug Interactions; Drugs, Chinese Herbal; Male; Rats; Rats, Wistar

2015
Simultaneous determination of tanshinones and polyphenolics in rat plasma by UPLC-MS/MS and its application to the pharmacokinetic interaction between them.
    Drug testing and analysis, 2016, Volume: 8, Issue:7

    Topics: Abietanes; Animals; Benzaldehydes; Benzofurans; Catechols; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Lactates; Limit of Detection; Liquid-Liquid Extraction; Male; Phenanthrenes; Polyphenols; Rats, Sprague-Dawley; Rosmarinic Acid; Tandem Mass Spectrometry

2016
[Optimization of method for determination of Salviae Miltiorrhizae Radix et Rhizoma].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:11

    Topics: Abietanes; Benzofurans; Chromatography, High Pressure Liquid; Rhizome; Salvia miltiorrhiza; Temperature

2015
Influence of naturaldecay of fibrousroots on growth and content of active compositions of Salvia miltiorrhiza f. alba.
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:13

    Topics: Abietanes; Benzofurans; Biomass; Chromatography, High Pressure Liquid; Plant Roots; Salvia miltiorrhiza

2015
Effects of salvianolic acid B and tanshinone IIA on the pharmacokinetics of losartan in rats by regulating the activities and expression of CYP3A4 and CYP2C9.
    Journal of ethnopharmacology, 2016, Mar-02, Volume: 180

    Topics: Abietanes; Animals; Antihypertensive Agents; Benzofurans; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Drug Interactions; Drugs, Chinese Herbal; Losartan; Male; Mass Spectrometry; Microsomes, Liver; Rats, Sprague-Dawley; RNA, Messenger

2016
[UPLC-MS/MS determination of tanshinone ⅡA, salvianolic acid B and ginsenoside Rg₁ in Fufang Danshen preparation in rat plasma and brain tissues].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:3

    Topics: Abietanes; Animals; Benzofurans; Brain; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ginsenosides; Male; Plasma; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry

2017
[Optimize ethanol-extraction procedure of Shenlian granules by orthogonal design with pharmacodynamics index].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:4

    Topics: Abietanes; Benzofurans; Berberine; Drugs, Chinese Herbal; Ethanol; Plants, Medicinal; Technology, Pharmaceutical

2017
Determination of quantitative retention-activity relationships between pharmacokinetic parameters and biological effectiveness fingerprints of Salvia miltiorrhiza constituents using biopartitioning and microemulsion high-performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Nov-01, Volume: 1067

    Topics: Abietanes; Animals; Area Under Curve; Benzofurans; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Drugs, Chinese Herbal; Emulsions; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Rosmarinic Acid; Salvia miltiorrhiza; Surface-Active Agents

2017
[Preparation and in vivo study of liposomes mediated by glycyrrhetinic acid derivative ligand 18-GA-Gly].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:21

    Topics: Abietanes; Animals; Benzofurans; Drug Carriers; Glycyrrhetinic Acid; Ligands; Liposomes; Liver

2017
Blue light decreases tanshinone IIA content in Salvia miltiorrhiza hairy roots via genes regulation.
    Journal of photochemistry and photobiology. B, Biology, 2018, Volume: 183

    Topics: Abietanes; Alkyl and Aryl Transferases; Benzofurans; Biomass; Chromatography, High Pressure Liquid; Farnesyltranstransferase; Gene Expression Regulation, Plant; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Light; Plant Proteins; Plant Roots; Salvia miltiorrhiza

2018
[Effect of Different Locations and Genotypes on Yield and Accumulation of Bioactive Constituents in Salvia miltiorrhiza].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2016, Volume: 39, Issue:9

    Topics: Abietanes; Benzofurans; Chromatography, High Pressure Liquid; Genotype; Hydroxybenzoates; Plant Roots; Salvia miltiorrhiza

2016
Development of sustained-release pellets to modulate the in vivo processes of the main active components of Danshen: A pharmacokinetic and pharmacodynamic evaluation.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 58

    Topics: Abietanes; Benzaldehydes; Benzofurans; Caffeic Acids; Capsules; Cardiovascular Diseases; Catechols; Delayed-Action Preparations; Drugs, Chinese Herbal; Humans; Hydrogen-Ion Concentration; Medicine, Chinese Traditional; Salvia miltiorrhiza

2019
Increased phenolic acid and tanshinone production and transcriptional responses of biosynthetic genes in hairy root cultures of Salvia przewalskii Maxim. treated with methyl jasmonate and salicylic acid.
    Molecular biology reports, 2020, Volume: 47, Issue:11

    Topics: Abietanes; Acetates; Benzofurans; Caffeic Acids; Cinnamates; Cyclopentanes; Depsides; Dose-Response Relationship, Drug; Gene Expression Regulation, Plant; Hydroxybenzoates; Oxylipins; Phenanthrenes; Plant Growth Regulators; Plant Proteins; Plant Roots; Rosmarinic Acid; Salicylic Acid; Salvia; Time Factors

2020
Application of smartphone in detection of thin-layer chromatography: Case of salvia miltiorrhiza.
    Journal of chromatography. A, 2021, Jan-25, Volume: 1637

    Topics: Abietanes; Benzofurans; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cinnamates; Depsides; Drugs, Chinese Herbal; Phenanthrenes; Quality Control; Rosmarinic Acid; Salvia miltiorrhiza; Smartphone

2021
Effect of main ingredients of Danhong Injection against oxidative stress induced autophagy injury via miR-19a/SIRT1 pathway in endothelial cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 83

    Topics: Abietanes; Apoptosis; Autophagy; Beclin-1; Benzofurans; Drugs, Chinese Herbal; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; MicroRNAs; Oxidative Stress; Sirtuin 1

2021
The effects of borneol on the pharmacokinetics and brain distribution of tanshinone IIA, salvianolic acid B and ginsenoside Rg
    Chinese journal of natural medicines, 2021, Volume: 19, Issue:2

    Topics: Abietanes; Animals; Benzofurans; Brain; Camphanes; Chromatography, Liquid; Drugs, Chinese Herbal; Ginsenosides; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry

2021
Extracts from Chinese herbs with anti-amyloid and neuroprotective activities.
    International journal of biological macromolecules, 2021, May-15, Volume: 179

    Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Anemarrhena; Benzofurans; Cell Line; China; Humans; Neuroprotective Agents; Peptide Fragments; Plant Extracts; Salvia miltiorrhiza; Spirostans

2021
[Preparation of salvianolic acid B, tanshinone Ⅱ_A, and glycyrrhetinic acid lipid emulsion and its protective effect against acute liver injury induced by acetaminophen].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:17

    Topics: Abietanes; Acetaminophen; Alanine Transaminase; Animals; Antipyretics; Aspartate Aminotransferases; Benzofurans; Chemical and Drug Induced Liver Injury; Depsides; Emulsions; Glycyrrhetinic Acid; Liver; Malondialdehyde; Mice

2022