tanshinone has been researched along with atorvastatin in 3 studies
| Studies (tanshinone) | Trials (tanshinone) | Recent Studies (post-2010) (tanshinone) | Studies (atorvastatin) | Trials (atorvastatin) | Recent Studies (post-2010) (atorvastatin) |
|---|---|---|---|---|---|
| 1,445 | 10 | 1,033 | 7,420 | 2,058 | 3,782 |
| Protein | Taxonomy | tanshinone (IC50) | atorvastatin (IC50) |
|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0064 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.0002 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0002 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0054 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 4.3 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Chen, S; Huang, H; Huang, Y; Liu, P; Liu, Z; Shen, X; Xu, S | 1 |
| Chen, Y; Gong, Z; Guo, Y; Li, Q; Li, Y; Liu, X; Wang, Y; Weng, X; Yang, Q; You, Y; Zhang, R; Zhou, B; Zhu, X | 1 |
| Hoi, MPM; Huang, B; Huang, XH; Lee, SMY; Li, S; Tang, JY; Zhou, ZY | 1 |
3 other study(ies) available for tanshinone and atorvastatin
| Article | Year |
|---|---|
Effectiveness of combination therapy of atorvastatin and non lipid-modifying tanshinone IIA from Danshen in a mouse model of atherosclerosis.
Topics: Abietanes; Animals; Atherosclerosis; Atorvastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drugs, Chinese Herbal; Heptanoic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrroles; Salvia miltiorrhiza; Treatment Outcome | 2014 |
Establishment of an interleukin-1β-induced inflammation-activated endothelial cell-smooth muscle cell-mononuclear cell co-culture model and evaluation of the anti-inflammatory effects of tanshinone IIA on atherosclerosis.
Topics: Abietanes; Anti-Inflammatory Agents; Atherosclerosis; Atorvastatin; Cell Proliferation; Cells, Cultured; Coculture Techniques; Connexins; Cytokines; Diterpenes; Endothelial Cells; Humans; Inflammation Mediators; Interleukin-1beta; Lipoproteins, LDL; Models, Biological; Myocytes, Smooth Muscle; NF-kappa B; Nitric Oxide; PPAR gamma | 2015 |
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell-cell adhesion by inhibiting VE-cadherin internalization and actin-myosin contractility.
Topics: Abietanes; Actins; Animals; Animals, Genetically Modified; Antigens, CD; Atorvastatin; Cadherins; Cell Adhesion; Cerebral Hemorrhage; Embryo, Nonmammalian; Human Umbilical Vein Endothelial Cells; Humans; Myosins; Protective Agents; Zebrafish | 2018 |