Compounds > tamibarotene
Page last updated: 2024-09-02

tamibarotene and vorinostat

tamibarotene has been researched along with vorinostat in 3 studies

Compound Research Comparison

Studies
(tamibarotene)		Trials
(tamibarotene)		Recent Studies (post-2010)
(tamibarotene)		Studies
(vorinostat)		Trials
(vorinostat)		Recent Studies (post-2010) (vorinostat)
198101052,5291811,840

Protein Interaction Comparison

ProteinTaxonomytamibarotene (IC50)vorinostat (IC50)
Chain A, Histone deacetylase-like amidohydrolaseAlcaligenaceae bacterium FB1880.95
Chain A, Histone deacetylase-like amidohydrolaseAlcaligenaceae bacterium FB1880.95
Histone deacetylase 8Schistosoma mansoni1.3147
Histone deacetylase Rattus norvegicus (Norway rat)0.165
Gli1Mus musculus (house mouse)2.23
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)0.7472
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)1.55
Histone deacetylase 1Mus musculus (house mouse)0.1121
Histone deacetylase 3Homo sapiens (human)0.3382
Bromodomain-containing protein 4Homo sapiens (human)0.2644
Nuclear receptor corepressor 1Homo sapiens (human)0.0382
Epidermal growth factor receptorHomo sapiens (human)0.456
Tubulin alpha-1A chainSus scrofa (pig)1.5
Tubulin beta chainSus scrofa (pig)1.5
AlbuminHomo sapiens (human)0.1072
Leukotriene A-4 hydrolaseHomo sapiens (human)4.66
Cytochrome P450 2C8Homo sapiens (human)0.0903
Cytochrome P450 2D6Homo sapiens (human)0.011
Cytochrome P450 2C9 Homo sapiens (human)0.24
Androgen receptorRattus norvegicus (Norway rat)0.1582
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)2.8
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.053
Cannabinoid receptor 1Rattus norvegicus (Norway rat)0.116
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)2.8
Leukotriene A-4 hydrolaseMus musculus (house mouse)6.15
Cytochrome P450 2C19Homo sapiens (human)0.042
Prostaglandin G/H synthase 2Homo sapiens (human)0.13
Delta-type opioid receptorHomo sapiens (human)7.2
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)2.8
Histamine H2 receptorCavia porcellus (domestic guinea pig)7.2
Histone deacetylase 4Homo sapiens (human)0.6096
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.086
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.322
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.1
Histone deacetylase 1Homo sapiens (human)0.2701
Histone deacetylase 1Rattus norvegicus (Norway rat)0.165
Histone deacetylase Rattus norvegicus (Norway rat)0.165
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.07
ReninMacaca fascicularis (crab-eating macaque)0.067
Histone deacetylase 3Rattus norvegicus (Norway rat)0.165
Histone deacetylase-like amidohydrolaseAlcaligenaceae bacterium FB1881
Histone deacetylase Plasmodium falciparum 3D70.1
Histone deacetylase 7Homo sapiens (human)0.6115
Histone deacetylase 2Homo sapiens (human)0.3746
HD2 type histone deacetylase HDA106 Zea mays0.2227
Polyamine deacetylase HDAC10Homo sapiens (human)0.4211
Histone deacetylase 11 Homo sapiens (human)0.5235
Carboxypeptidase B2Homo sapiens (human)0.362
Histone deacetylase 7Rattus norvegicus (Norway rat)0.165
Histone deacetylase 6 Rattus norvegicus (Norway rat)0.165
Histone deacetylase 4Rattus norvegicus (Norway rat)0.165
Histone deacetylase 8Homo sapiens (human)0.9141
Histone deacetylase 6Homo sapiens (human)0.2634
Histone deacetylase 9Homo sapiens (human)0.5614
Histone deacetylase 5Homo sapiens (human)0.5926
Histone deacetylase Plasmodium falciparum (malaria parasite P. falciparum)0.0945
Nuclear receptor corepressor 2Homo sapiens (human)0.0905
Histone deacetylase 6Mus musculus (house mouse)0.3742
Histone deacetylase Zea mays0.029

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chou, CJ; Liu, C; Wang, X; Xu, W; Yang, P; Zhang, Y1
Jiang, Y; Li, X; Wang, X; Wang, Z; Wu, J; Xu, W; Zhang, J1
Ekimoto, H; Ishigami-Yuasa, M; Kagechika, H1

Other Studies

3 other study(ies) available for tamibarotene and vorinostat

ArticleYear
Development of
    ACS medicinal chemistry letters, 2013, Feb-14, Volume: 4, Issue:2

    Topics:

2013
Design, synthesis, and biological characterization of tamibarotene analogs as anticancer agents.
    Chemical biology & drug design, 2016, Volume: 88, Issue:4

    Topics: Animals; Antineoplastic Agents; Benzoates; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Drug Design; Drug Stability; Humans; Rats; Tetrahydronaphthalenes

2016
Class IIb HDAC Inhibition Enhances the Inhibitory Effect of Am80, a Synthetic Retinoid, in Prostate Cancer.
    Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:3

    Topics: Antineoplastic Agents; Benzoates; Cell Line, Tumor; Decitabine; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Male; Prostatic Neoplasms; Pyridines; Receptors, Retinoic Acid; Sulfonamides; Tetrahydronaphthalenes; Vorinostat

2019