talotrexin has been researched along with novobiocin in 1 studies
| Studies (talotrexin) | Trials (talotrexin) | Recent Studies (post-2010) (talotrexin) | Studies (novobiocin) | Trials (novobiocin) | Recent Studies (post-2010) (novobiocin) |
|---|---|---|---|---|---|
| 27 | 0 | 4 | 2,271 | 15 | 290 |
| Protein | Taxonomy | talotrexin (IC50) | novobiocin (IC50) |
|---|---|---|---|
| DNA gyrase subunit B | Mycolicibacterium smegmatis MC2 155 | 0.046 | |
| DNA gyrase subunit B | Staphylococcus aureus | 0.0474 | |
| DNA gyrase subunit B | Streptococcus pneumoniae TIGR4 | 0.037 | |
| DNA gyrase subunit A | Escherichia coli K-12 | 0.1441 | |
| DNA gyrase subunit B | Escherichia coli K-12 | 0.1537 | |
| DNA topoisomerase 4 subunit B | Staphylococcus aureus | 7.9 | |
| DNA gyrase subunit B | Mycolicibacterium smegmatis | 0.161 | |
| DNA gyrase subunit A | Staphylococcus aureus | 0.0383 | |
| DNA gyrase subunit B | Mycobacterium tuberculosis H37Rv | 0.0446 | |
| DNA gyrase subunit A | Mycobacterium tuberculosis H37Rv | 0.1315 | |
| DNA topoisomerase | Streptococcus pneumoniae | 2.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holden, SA; Northey, D; Robinson, MF; Rosowsky, A; Teicher, BA | 1 |
1 other study(ies) available for talotrexin and novobiocin
| Article | Year |
|---|---|
Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Etoposide; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Mice, Inbred C3H; Novobiocin; Ornithine; Pterins; Topoisomerase II Inhibitors; Trimetrexate; Tumor Cells, Cultured | 1995 |