Page last updated: 2024-09-03

talotrexin and leucovorin

talotrexin has been researched along with leucovorin in 2 studies

Compound Research Comparison

Studies (talotrexin)	Trials (talotrexin)	Recent Studies (post-2010) (talotrexin)	Studies (leucovorin)	Trials (leucovorin)	Recent Studies (post-2010) (leucovorin)
27	0	4	20	0	5

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cherian, C; Deng, Y; Desmoulin, SK; Gangjee, A; Hou, Z; Kushner, J; Matherly, LH; Polin, L; Wang, L; White, K; Wu, J	1
Chang, MH; Cherian, C; Desmoulin, SK; Fulterer, A; Gangjee, A; Hou, Z; Kushner, J; Matherly, LH; Mitchell-Ryan, S; Polin, L; Romero, MF; Stout, M; Wang, L; White, K	1

Other Studies

2 other study(ies) available for talotrexin and leucovorin

Article	Year
Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduc Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Carrier Proteins; Cell Proliferation; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Female; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Humans; Membrane Transport Proteins; Mice; Mice, Inbred ICR; Mice, SCID; Ovarian Neoplasms; Proton-Coupled Folate Transporter; Purines; Pyrimidines; Receptors, Cell Surface; Reduced Folate Carrier Protein	2010
Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-gl Journal of medicinal chemistry, 2011, Oct-27, Volume: 54, Issue:20 Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Folate Receptor 1; Folate Receptor 2; Folic Acid Antagonists; Glutamates; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Oocytes; Patch-Clamp Techniques; Phosphoribosylglycinamide Formyltransferase; Proton-Coupled Folate Transporter; Pyrimidines; Pyrimidinones; Reduced Folate Carrier Protein; Stereoisomerism; Structure-Activity Relationship; Transplantation, Heterologous; Xenopus	2011

Article

Year

Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduc

Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Carrier Proteins; Cell Proliferation; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Female; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Humans; Membrane Transport Proteins; Mice; Mice, Inbred ICR; Mice, SCID; Ovarian Neoplasms; Proton-Coupled Folate Transporter; Purines; Pyrimidines; Receptors, Cell Surface; Reduced Folate Carrier Protein

2010

Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-gl

Journal of medicinal chemistry, 2011, Oct-27, Volume: 54, Issue:20

Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Folate Receptor 1; Folate Receptor 2; Folic Acid Antagonists; Glutamates; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Oocytes; Patch-Clamp Techniques; Phosphoribosylglycinamide Formyltransferase; Proton-Coupled Folate Transporter; Pyrimidines; Pyrimidinones; Reduced Folate Carrier Protein; Stereoisomerism; Structure-Activity Relationship; Transplantation, Heterologous; Xenopus

2011