Compounds > talotrexin
Page last updated: 2024-09-03

talotrexin and folic acid

talotrexin has been researched along with folic acid in 4 studies

Compound Research Comparison

Studies
(talotrexin)		Trials
(talotrexin)		Recent Studies (post-2010)
(talotrexin)		Studies
(folic acid)		Trials
(folic acid)		Recent Studies (post-2010) (folic acid)
270430,0011,94510,195

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Galivan, J; Rhee, MS; Rosowsky, A; Wright, JE1
Forsch, RA; Rosowsky, A; Vaidya, CM; Wright, JE1
Assaraf, YG; Bunni, MA; Drori, S; Jansen, G; Kathmann, I; Mauritz, R; Noordhuis, P; Peters, GJ; Pinedo, HM; Priest, DG; Rosowsky, A; Schornagel, JH1
Frühauf, J; Gangjee, A; Hou, Z; Matherly, LH; Ning, C; O'Connor, C; Tong, N; Wallace-Povirk, A1

Other Studies

4 other study(ies) available for talotrexin and folic acid

ArticleYear
Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Molecular pharmacology, 1994, Volume: 45, Issue:4

    Topics: Animals; Biological Transport; DNA, Neoplasm; Folic Acid; Folic Acid Antagonists; Growth Inhibitors; In Vitro Techniques; Liver Neoplasms, Experimental; Methotrexate; Ornithine; Polyglutamic Acid; Pterins; Rats; Tumor Cells, Cultured

1994
The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta
    Pharmacology & therapeutics, 2000, Volume: 85, Issue:3

    Topics: 4-Aminobenzoic Acid; Aminopterin; Antineoplastic Agents; Binding Sites; Cell Division; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Humans; Ornithine; Pterins; Reducing Agents; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured

2000
Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
    Biochemical pharmacology, 2002, Jan-15, Volume: 63, Issue:2

    Topics: Biological Transport; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; gamma-Glutamyl Hydrolase; Glutamates; Guanine; Homeostasis; Humans; Leukemia; Methotrexate; Ornithine; Pemetrexed; Peptide Synthases; Polyglutamic Acid; Pterins; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured

2002
Folate transporter dynamics and therapy with classic and tumor-targeted antifolates.
    Scientific reports, 2021, 03-18, Volume: 11, Issue:1

    Topics: Biological Transport; Cell Proliferation; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; HeLa Cells; Humans; Methotrexate; Neoplasms; Ornithine; Pemetrexed; Proton-Coupled Folate Transporter; Pterins; Reduced Folate Carrier Protein

2021