tak 779 and aplaviroc
tak 779 has been researched along with aplaviroc in 4 studies
Compound Research Comparison
| Studies (tak 779) | Trials (tak 779) | Recent Studies (post-2010) (tak 779) | Studies (aplaviroc) | Trials (aplaviroc) | Recent Studies (post-2010) (aplaviroc) |
|---|---|---|---|---|---|
| 118 | 1 | 35 | 38 | 8 | 8 |
Protein Interaction Comparison
| Protein | Taxonomy | tak 779 (IC50) | aplaviroc (IC50) |
|---|---|---|---|
| C-C chemokine receptor type 5 | Mus musculus (house mouse) | 0.0004 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Horuk, R; Pease, J | 1 |
| Dioszegi, M; Ji, C; Kondru, R; Mirzadegan, T; Rotstein, D; Sankuratri, S; Zhang, J | 1 |
| Arenzana-Seisdedos, F | 1 |
| Frimurer, TM; Jensen, PC; Mokrosinski, J; Rosenkilde, MM; Steen, A; Thiele, S | 1 |
Reviews
1 review(s) available for tak 779 and aplaviroc
| Article | Year |
|---|---|
[Viral entry as therapeutic target. Current situation of entry inhibitors].
Topics: Adult; Amides; Benzoates; CCR5 Receptor Antagonists; CD4 Antigens; Chemokines, CC; Chemokines, CXC; Clinical Trials as Topic; Cyclohexanes; Diketopiperazines; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Membrane Fusion; Models, Molecular; Piperazines; Pyrimidines; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; Spiro Compounds; Structure-Activity Relationship; Triazoles; Virus Attachment; Virus Internalization | 2008 |
Other Studies
3 other study(ies) available for tak 779 and aplaviroc
| Article | Year |
|---|---|
Chemokine receptor antagonists.
Topics: Animals; Autoimmune Diseases; Humans; Receptors, Chemokine | 2012 |
Molecular interactions of CCR5 with major classes of small-molecule anti-HIV CCR5 antagonists.
Topics: Amides; Amino Acid Sequence; Animals; Anti-HIV Agents; Benzoates; Binding Sites; CCR5 Receptor Antagonists; CHO Cells; Cricetinae; Cricetulus; Cyclohexanes; Diketopiperazines; HIV Fusion Inhibitors; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Maraviroc; Membrane Fusion; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Piperazines; Piperidines; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; Quaternary Ammonium Compounds; Radioligand Assay; Receptors, CCR5; Sequence Homology, Amino Acid; Spiro Compounds; Static Electricity; Transfection; Triazoles | 2008 |
Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach.
Topics: Allosteric Regulation; Amides; Animals; Benzoates; Chemokines; Chlorocebus aethiops; COS Cells; Cyclic N-Oxides; Diketopiperazines; Humans; Oximes; Piperazines; Piperidines; Pyridines; Quaternary Ammonium Compounds; Receptors, CCR2; Receptors, CCR5; Recombinant Fusion Proteins; Spiro Compounds | 2011 |