Page last updated: 2024-09-05

tak 779 and aplaviroc

tak 779 has been researched along with aplaviroc in 4 studies

Compound Research Comparison

Studies (tak 779)	Trials (tak 779)	Recent Studies (post-2010) (tak 779)	Studies (aplaviroc)	Trials (aplaviroc)	Recent Studies (post-2010) (aplaviroc)
118	1	35	38	8	8

Protein Interaction Comparison

Protein	Taxonomy	tak 779 (IC50)	aplaviroc (IC50)
C-C chemokine receptor type 5	Mus musculus (house mouse)		0.0004

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	2 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Horuk, R; Pease, J	1
Dioszegi, M; Ji, C; Kondru, R; Mirzadegan, T; Rotstein, D; Sankuratri, S; Zhang, J	1
Arenzana-Seisdedos, F	1
Frimurer, TM; Jensen, PC; Mokrosinski, J; Rosenkilde, MM; Steen, A; Thiele, S	1

Reviews

1 review(s) available for tak 779 and aplaviroc

Article	Year
[Viral entry as therapeutic target. Current situation of entry inhibitors]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11 Topics: Adult; Amides; Benzoates; CCR5 Receptor Antagonists; CD4 Antigens; Chemokines, CC; Chemokines, CXC; Clinical Trials as Topic; Cyclohexanes; Diketopiperazines; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Membrane Fusion; Models, Molecular; Piperazines; Pyrimidines; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; Spiro Compounds; Structure-Activity Relationship; Triazoles; Virus Attachment; Virus Internalization	2008

Article

Year

[Viral entry as therapeutic target. Current situation of entry inhibitors].

Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

Topics: Adult; Amides; Benzoates; CCR5 Receptor Antagonists; CD4 Antigens; Chemokines, CC; Chemokines, CXC; Clinical Trials as Topic; Cyclohexanes; Diketopiperazines; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Membrane Fusion; Models, Molecular; Piperazines; Pyrimidines; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; Spiro Compounds; Structure-Activity Relationship; Triazoles; Virus Attachment; Virus Internalization

2008

Other Studies

3 other study(ies) available for tak 779 and aplaviroc

Article	Year
Chemokine receptor antagonists. Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22 Topics: Animals; Autoimmune Diseases; Humans; Receptors, Chemokine	2012
Molecular interactions of CCR5 with major classes of small-molecule anti-HIV CCR5 antagonists. Molecular pharmacology, 2008, Volume: 73, Issue:3 Topics: Amides; Amino Acid Sequence; Animals; Anti-HIV Agents; Benzoates; Binding Sites; CCR5 Receptor Antagonists; CHO Cells; Cricetinae; Cricetulus; Cyclohexanes; Diketopiperazines; HIV Fusion Inhibitors; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Maraviroc; Membrane Fusion; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Piperazines; Piperidines; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; Quaternary Ammonium Compounds; Radioligand Assay; Receptors, CCR5; Sequence Homology, Amino Acid; Spiro Compounds; Static Electricity; Transfection; Triazoles	2008
Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach. The Journal of biological chemistry, 2011, Oct-28, Volume: 286, Issue:43 Topics: Allosteric Regulation; Amides; Animals; Benzoates; Chemokines; Chlorocebus aethiops; COS Cells; Cyclic N-Oxides; Diketopiperazines; Humans; Oximes; Piperazines; Piperidines; Pyridines; Quaternary Ammonium Compounds; Receptors, CCR2; Receptors, CCR5; Recombinant Fusion Proteins; Spiro Compounds	2011