tafenoquine has been researched along with mefloquine in 14 studies
| Studies (tafenoquine) | Trials (tafenoquine) | Recent Studies (post-2010) (tafenoquine) | Studies (mefloquine) | Trials (mefloquine) | Recent Studies (post-2010) (mefloquine) |
|---|---|---|---|---|---|
| 186 | 37 | 113 | 71 | 0 | 66 |
| 186 | 37 | 113 | 2,212 | 342 | 560 |
| Protein | Taxonomy | tafenoquine (IC50) | mefloquine (IC50) |
|---|---|---|---|
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 2.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Fidock, DA; Flannery, EL; Winzeler, EA | 1 |
| Avery, VM; Sykes, ML | 1 |
| Trigg, PI | 1 |
| Fleck, SL; Peters, W; Robinson, BL | 1 |
| Peters, W; Robinson, BL; Stewart, LB | 1 |
| Chambers, JA | 1 |
| Brennan, L; Edstein, MD; Harris, IE; Kerr, C; Kitchener, SJ; Leggat, PA; Nasveld, PE; Ohrt, C; Pickford, P; Prescott, W; Reid, M | 1 |
| Imre, T; Iványi, R; Jicsinszky, L; Mizsei, R; Németh, K; Simonyi, M; Szemán, J; Szente, L; Tárkányi, G; Varga, E; Visy, J | 1 |
| Cozens, S; Dow, GS; Gettayacamin, M; Hansukjariya, P; Imerbsin, R; Kenworthy, D; Komcharoen, S; Kyle, D; Milhous, W; Miller, A; Ohrt, C; Sattabongkot, J; Veazey, J | 1 |
| Baresel, PC; Campo, B; Magill, AJ; Ohrt, C; Rochford, R; Sampath, A; Tekwani, BL; Walker, LA | 1 |
| Dow, GS; McCarthy, WF; Reid, M; Shanks, GD; Smith, B; Tang, D | 1 |
| Dow, GS; Hetzell, B; Lin, G; Liu, J; McCarthy, WF; Smith, B; Tang, D; Thieling, S | 1 |
| Carvalho, LJM; Nugraha, AB; Sivakumar, T; Tuvshintulga, B; Yokoyama, N | 1 |
| Clark, J; Clements, ACA; Doi, SAR; Furuya-Kanamori, L; Islam, N; Lau, CL; Mills, DJ; Wright, S | 1 |
4 review(s) available for tafenoquine and mefloquine
| Article | Year |
|---|---|
Using genetic methods to define the targets of compounds with antimalarial activity.
Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum | 2013 |
Approaches to protozoan drug discovery: phenotypic screening.
Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi | 2013 |
Military aviators, special operations forces, and causal malaria prophylaxis.
Topics: Aminoquinolines; Antimalarials; Atovaquone; Aviation; Chloroquine; Doxycycline; Drug Combinations; Humans; Malaria; Mefloquine; Military Personnel; Naphthoquinones; Primaquine; Proguanil; United States | 2003 |
Efficacy of a 3-day pretravel schedule of tafenoquine for malaria chemoprophylaxis: a network meta-analysis.
Topics: Aminoquinolines; Antimalarials; Humans; Malaria; Mefloquine; Network Meta-Analysis; Travel | 2021 |
2 trial(s) available for tafenoquine and mefloquine
| Article | Year |
|---|---|
Randomized, double-blind study of the safety, tolerability, and efficacy of tafenoquine versus mefloquine for malaria prophylaxis in nonimmune subjects.
Topics: Adult; Aminoquinolines; Antimalarials; Australia; Double-Blind Method; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Military Personnel; Treatment Outcome; Young Adult | 2010 |
Summary of anti-malarial prophylactic efficacy of tafenoquine from three placebo-controlled studies of residents of malaria-endemic countries.
Topics: Adolescent; Adult; Africa; Aminoquinolines; Antimalarials; Chemoprevention; Double-Blind Method; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Placebos; Treatment Outcome; Young Adult | 2015 |
8 other study(ies) available for tafenoquine and mefloquine
| Article | Year |
|---|---|
Drug use and design in the nineties.
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine | 1991 |
The chemotherapy of rodent malaria. LIV. Combinations of 'Fenozan B07' (Fenozan-50F), a difluorinated 3,3'-spirocyclopentane 1,2,4-trioxane, with other drugs against drug-sensitive and drug-resistant parasites.
Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Drug Antagonism; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Malaria; Mefloquine; Mice; Naphthyridines; Parasitemia; Phenanthrenes; Phenylpropionates; Plasmodium berghei; Plasmodium yoelii | 1997 |
The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines.
Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Resistance; Drug Therapy, Combination; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Mice; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Primaquine; Time Factors | 2003 |
Enantiomeric separation of antimalarial drugs by capillary electrophoresis using neutral and negatively charged cyclodextrins.
Topics: Aminoquinolines; Anions; Antimalarials; beta-Cyclodextrins; Chloroquine; Cyclodextrins; Electrophoresis, Capillary; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mefloquine; Primaquine; Stereoisomerism | 2011 |
Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta).
Topics: Aminoquinolines; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Macaca mulatta; Malaria; Male; Mass Spectrometry; Mefloquine; Plasma; Plasmodium cynomolgi; Primate Diseases; Quinine; Treatment Outcome | 2011 |
Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.
Topics: Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Combined Modality Therapy; Dapsone; Dose-Response Relationship, Drug; Doxycycline; Drug Evaluation, Preclinical; Erythrocyte Count; Erythrocyte Transfusion; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Mefloquine; Mice; Mice, Inbred NOD; Mice, SCID; Primaquine; Pyrimethamine; Reproducibility of Results; Sensitivity and Specificity; Transplantation, Heterologous | 2013 |
A retrospective analysis of the protective efficacy of tafenoquine and mefloquine as prophylactic anti-malarials in non-immune individuals during deployment to a malaria-endemic area.
Topics: Aminoquinolines; Antimalarials; Australia; Chemoprevention; Endemic Diseases; Humans; Incidence; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Military Personnel; Retrospective Studies; Timor-Leste; Travel; Treatment Outcome; United States | 2014 |
Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo.
Topics: Aminoquinolines; Animals; Antimalarials; Artesunate; Babesia bovis; Babesia microti; Babesiosis; Disease Models, Animal; Drug Combinations; In Vitro Techniques; Lumefantrine; Mefloquine; Methylene Blue; Mice; Mice, Inbred BALB C | 2020 |