tafenoquine has been researched along with amodiaquine hydrochloride in 4 studies
| Studies (tafenoquine) | Trials (tafenoquine) | Recent Studies (post-2010) (tafenoquine) | Studies (amodiaquine hydrochloride) | Trials (amodiaquine hydrochloride) | Recent Studies (post-2010) (amodiaquine hydrochloride) |
|---|---|---|---|---|---|
| 186 | 37 | 113 | 68 | 2 | 22 |
| Protein | Taxonomy | tafenoquine (IC50) | amodiaquine hydrochloride (IC50) |
|---|---|---|---|
| Cytochrome P450 2C8 | Homo sapiens (human) | 2.7 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 6.1 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 2.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fitos, I; Mády, G; Visy, J; Zsila, F | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fidock, DA; Flannery, EL; Winzeler, EA | 1 |
| Avery, VM; Sykes, ML | 1 |
2 review(s) available for tafenoquine and amodiaquine hydrochloride
| Article | Year |
|---|---|
Using genetic methods to define the targets of compounds with antimalarial activity.
Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum | 2013 |
Approaches to protozoan drug discovery: phenotypic screening.
Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi | 2013 |
2 other study(ies) available for tafenoquine and amodiaquine hydrochloride
| Article | Year |
|---|---|
Selective plasma protein binding of antimalarial drugs to alpha1-acid glycoprotein.
Topics: Antimalarials; Binding Sites; Chromatography, Affinity; Circular Dichroism; Humans; Molecular Structure; Orosomucoid; Protein Binding; Serum Albumin; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |