Page last updated: 2024-09-02

tadalafil and trazodone

tadalafil has been researched along with trazodone in 2 studies

Compound Research Comparison

Studies
(tadalafil)
Trials
(tadalafil)
Recent Studies (post-2010)
(tadalafil)
Studies
(trazodone)
Trials
(trazodone)
Recent Studies (post-2010) (trazodone)
1,7423921,0891,466295312

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)trazodone (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.091
Alpha-2A adrenergic receptorHomo sapiens (human)0.909
D(2) dopamine receptorHomo sapiens (human)4.485
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.017
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.281
Alpha-2B adrenergic receptorHomo sapiens (human)0.389
Alpha-2C adrenergic receptorHomo sapiens (human)1.942
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.311
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.281
Alpha-1D adrenergic receptorHomo sapiens (human)0.265
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.1315
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.091
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.311
Sodium-dependent serotonin transporterHomo sapiens (human)0.192
Histamine H1 receptorHomo sapiens (human)0.361
D(3) dopamine receptorHomo sapiens (human)3.743
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.107
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.281
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.203

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for tadalafil and trazodone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for tadalafil and trazodone

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013