Compounds > tadalafil
Page last updated: 2024-09-02

tadalafil and thioridazine

tadalafil has been researched along with thioridazine in 1 studies

Compound Research Comparison

Studies
(tadalafil)		Trials
(tadalafil)		Recent Studies (post-2010)
(tadalafil)		Studies
(thioridazine)		Trials
(thioridazine)		Recent Studies (post-2010) (thioridazine)
1,7423921,0892,501255207

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)thioridazine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)1.32
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)3.5
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.044
Epidermal growth factor receptorHomo sapiens (human)2.947
AlbuminHomo sapiens (human)3.5
Cytochrome P450 1A2Homo sapiens (human)9.3323
Tyrosine-protein kinase FynHomo sapiens (human)5.05
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.551
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.106
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.08
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.106
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.106
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.106
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.039
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.106
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0092
Alpha-2A adrenergic receptorHomo sapiens (human)0.133
Tryptophan 5-hydroxylase 1Rattus norvegicus (Norway rat)0.06
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.69
Cytochrome P450 2D6Homo sapiens (human)1.7726
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.106
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.007
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)1.588
D(2) dopamine receptorHomo sapiens (human)0.035
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.039
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.065
Alpha-2B adrenergic receptorHomo sapiens (human)0.38
Alpha-2C adrenergic receptorHomo sapiens (human)0.171
DRattus norvegicus (Norway rat)0.3046
D(3) dopamine receptorRattus norvegicus (Norway rat)0.085
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.06
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0355
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.09
D(1A) dopamine receptorHomo sapiens (human)0.194
D(4) dopamine receptorHomo sapiens (human)1.468
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0355
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0355
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.065
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.551
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.0355
Histamine H2 receptorHomo sapiens (human)0.95
Alpha-1D adrenergic receptorHomo sapiens (human)0.0059
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.085
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0044
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.044
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.06
D(4) dopamine receptorRattus norvegicus (Norway rat)0.085
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.039
Histamine H1 receptorRattus norvegicus (Norway rat)0.099
Sodium-dependent serotonin transporterHomo sapiens (human)0.751
Cytochrome P450 2C19Homo sapiens (human)6.3778
Pleiotropic ABC efflux transporter of multiple drugsSaccharomyces cerevisiae S288C1.3
Histamine H1 receptorHomo sapiens (human)0.072
D(3) dopamine receptorHomo sapiens (human)0.0099
Kappa-type opioid receptorHomo sapiens (human)2.49
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.129
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.065
5-hydroxytryptamine receptor 6Homo sapiens (human)0.071
D(2) dopamine receptorRattus norvegicus (Norway rat)0.059
Cathepsin D Bos taurus (cattle)0.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)3.5
Sodium-dependent dopamine transporter Homo sapiens (human)2.376
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2498
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)3.5
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)2.41
Sodium channel protein type 5 subunit alphaHomo sapiens (human)1.83
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)1.588
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.363
Sigma non-opioid intracellular receptor 1Rattus norvegicus (Norway rat)0.75
Mucosa-associated lymphoid tissue lymphoma translocation protein 1Homo sapiens (human)3.765
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6.6

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for tadalafil and thioridazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016