Compounds > tadalafil
Page last updated: 2024-09-02

tadalafil and propafenone

tadalafil has been researched along with propafenone in 4 studies

Compound Research Comparison

Studies
(tadalafil)		Trials
(tadalafil)		Recent Studies (post-2010)
(tadalafil)		Studies
(propafenone)		Trials
(propafenone)		Recent Studies (post-2010) (propafenone)
1,7423921,0891,471268239

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)propafenone (IC50)
Potassium channel subfamily K member 3Homo sapiens (human)5.1
ATP-binding cassette sub-family C member 9Homo sapiens (human)2.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.384
Potassium channel subfamily K member 2Homo sapiens (human)7.6
Cytochrome P450 1A2Homo sapiens (human)3.292
Beta-2 adrenergic receptorHomo sapiens (human)0.052
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.016
ATP-dependent translocase ABCB1Homo sapiens (human)0.3311
Beta-1 adrenergic receptorHomo sapiens (human)0.354
Cytochrome P450 2D6Homo sapiens (human)4.6034
Beta-3 adrenergic receptorHomo sapiens (human)0.424
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.637
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.016
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.654
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.384
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.637
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.092
5-hydroxytryptamine receptor 6Homo sapiens (human)1.863
Sodium-dependent dopamine transporter Homo sapiens (human)1.868
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.3733
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.245
ATP-sensitive inward rectifier potassium channel 11Homo sapiens (human)2.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.61

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bischoff-Kont, I; Chaikuad, A; Faudone, G; Fürst, R; Heering, J; Kaiser, A; Knapp, S; Merk, D; Rachor, L; Willems, S; Zhubi, R1

Reviews

1 review(s) available for tadalafil and propafenone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for tadalafil and propafenone

ArticleYear
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Propranolol Activates the Orphan Nuclear Receptor TLX to Counteract Proliferation and Migration of Glioblastoma Cells.
    Journal of medicinal chemistry, 2021, 06-24, Volume: 64, Issue:12

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioblastoma; HEK293 Cells; Humans; Molecular Structure; Orphan Nuclear Receptors; Propranolol; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship

2021