Compounds > tadalafil
Page last updated: 2024-09-02

tadalafil and pentoxifylline

tadalafil has been researched along with pentoxifylline in 9 studies

Compound Research Comparison

Studies
(tadalafil)		Trials
(tadalafil)		Recent Studies (post-2010)
(tadalafil)		Studies
(pentoxifylline)		Trials
(pentoxifylline)		Recent Studies (post-2010) (pentoxifylline)
1,7423921,0894,437657943

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)pentoxifylline (IC50)
AcetylcholinesteraseHomo sapiens (human)6.6

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Wald, M1
Ciociola, F; Colpi, GM1
Aziret, M; Cetinkunar, S; Deger, KC; Demirturk, P; Erdem, H; Irkorucu, O; Ozkara, S; Reyhan, E; Sehirli, AO; Surmelioglu, A1
Agrawal, S; Jayant, K; Kumar, S; Mavuduru, RS; Roat, R1
Bahadir, B; Bektas, S; Can, M; Erdogan, N; Guven, B; Karakaya, K; Ozdamar, SO1
Abd Al Haleem, EN; Arafa, HMM; Ibrahim, FAM; Zaytoon, SAB1
Amin, A; Habib, HA; Heeba, GH; Othman, EM; Zahran, ME1

Reviews

1 review(s) available for tadalafil and pentoxifylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for tadalafil and pentoxifylline

ArticleYear
Combination Therapy Of Tadalafil And Pentoxifylline In Severe Erectile Dysfunction; A Prospective Randomized Trial.
    Polski przeglad chirurgiczny, 2015, Volume: 87, Issue:8

    Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Middle Aged; Pentoxifylline; Prospective Studies; Severity of Illness Index; Tadalafil; Treatment Outcome; Vasodilator Agents

2015

Other Studies

7 other study(ies) available for tadalafil and pentoxifylline

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Enhancement of human sperm motility.
    The Journal of urology, 2008, Volume: 180, Issue:2

    Topics: Carbolines; Humans; Infertility, Male; Kallidin; Kallikreins; Male; Pentoxifylline; Sensitivity and Specificity; Sperm Count; Sperm Motility; Stimulation, Chemical; Tadalafil; Treatment Outcome

2008
Peyronie's disease: a "triple oxygenant therapy".
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2013, Apr-19, Volume: 85, Issue:1

    Topics: Arginine; Carbolines; Drug Therapy, Combination; Free Radical Scavengers; Humans; Male; Penile Induration; Pentoxifylline; Phosphodiesterase 5 Inhibitors; Tadalafil; Young Adult

2013
Efficacy of pentoxifylline and tadalafil in rat model of ischemic colitis.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2014, Volume: 27, Issue:6

    Topics: Animals; Carbolines; Colitis, Ischemic; Colon; Disease Models, Animal; Female; Laparotomy; Malondialdehyde; Pentoxifylline; Phosphodiesterase 5 Inhibitors; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Tadalafil; Treatment Outcome

2014
The effects of tadalafil and pentoxifylline on apoptosis and nitric oxide synthase in liver ischemia/reperfusion injury.
    The Kaohsiung journal of medical sciences, 2016, Volume: 32, Issue:7

    Topics: Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Female; Immunohistochemistry; Liver; Nitric Oxide Synthase; Pentoxifylline; Rats, Wistar; Reperfusion Injury; Tadalafil

2016
Possible protective effect of TNF-α inhibition and triad NO/cGMP/VEGF activation on gastric ulcer in rats.
    Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:9

    Topics: Animals; Cyclic GMP; Dinoprostone; Indomethacin; Male; Malondialdehyde; Nitric Oxide; Pentoxifylline; Rats; Stomach Ulcer; Tadalafil; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2021
Mechanistic Protective Effect of Cilostazol in Cisplatin-Induced Testicular Damage via Regulation of Oxidative Stress and TNF-α/NF-κB/Caspase-3 Pathways.
    International journal of molecular sciences, 2023, Aug-10, Volume: 24, Issue:16

    Topics: Animals; Caspase 3; Cilostazol; Cisplatin; Inflammation; Male; NF-kappa B; Oxidative Stress; Pentoxifylline; Phosphodiesterase 3 Inhibitors; Rats; Semen; Tadalafil; Tumor Necrosis Factor-alpha

2023