Page last updated: 2024-09-02

tadalafil and nitrendipine

tadalafil has been researched along with nitrendipine in 2 studies

Compound Research Comparison

Studies
(tadalafil)
Trials
(tadalafil)
Recent Studies (post-2010)
(tadalafil)
Studies
(nitrendipine)
Trials
(nitrendipine)
Recent Studies (post-2010) (nitrendipine)
1,7423921,0892,17037883

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)nitrendipine (IC50)
G-protein coupled receptor 55Homo sapiens (human)1.4652
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.0152
Cytochrome P450 2C9 Homo sapiens (human)0.3
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0013
Voltage-dependent L-type calcium channel subunit alpha-1DRattus norvegicus (Norway rat)0.0013
Cytochrome P450 2C19Homo sapiens (human)3
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.0152
Voltage-dependent L-type calcium channel subunit alpha-1SRattus norvegicus (Norway rat)0.0013
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)10
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.0152
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0152
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)1.85

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Jung, F; Leithäuser, B; Park, JW1

Trials

1 trial(s) available for tadalafil and nitrendipine

ArticleYear
Sublingual application of liquid nitrendipine does not result in critical hypotension in healthy volunteers under phosphodiesterase-5 inhibition.
    Clinical hemorheology and microcirculation, 2008, Volume: 39, Issue:1-4

    Topics: Administration, Sublingual; Adult; Angina Pectoris; Blood Pressure; Carbolines; Cardiovascular Diseases; Dosage Forms; Drug Interactions; Erectile Dysfunction; Humans; Hypotension; Male; Nitrendipine; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Tadalafil

2008

Other Studies

1 other study(ies) available for tadalafil and nitrendipine

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013