Page last updated: 2024-09-02

tadalafil and naproxen

tadalafil has been researched along with naproxen in 3 studies

Compound Research Comparison

Studies
(tadalafil)
Trials
(tadalafil)
Recent Studies (post-2010)
(tadalafil)
Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010) (naproxen)
1,7423921,0894,5511,0571,429

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)naproxen (IC50)
Prostaglandin G/H synthase 1Ovis aries (sheep)1.1642
Hormone-sensitive lipaseRattus norvegicus (Norway rat)1.2
Prostaglandin G/H synthase 1Homo sapiens (human)4.0203
Prostaglandin G/H synthase 2Homo sapiens (human)3.8725
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.06
Aldo-keto reductase family 1 member C3Homo sapiens (human)0.5867
Aldo-keto reductase family 1 member C2 Homo sapiens (human)1.26
Prostaglandin G/H synthase 2Ovis aries (sheep)3.36
Solute carrier family 22 member 6Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.06

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
McClain, SA; Singer, AJ; Towery, H1

Reviews

1 review(s) available for tadalafil and naproxen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for tadalafil and naproxen

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effect of tadalafil on reduction of necrosis in the ischemic zone in a rat comb burn model.
    Burns : journal of the International Society for Burn Injuries, 2018, Volume: 44, Issue:6

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Disease Models, Animal; Disease Progression; Free Radical Scavengers; Ischemia; Naproxen; Necrosis; Random Allocation; Rats; Rats, Sprague-Dawley; Skin; Tadalafil; Vasodilator Agents

2018