Page last updated: 2024-09-02

tadalafil and malondialdehyde

tadalafil has been researched along with malondialdehyde in 22 studies

Compound Research Comparison

Studies
(tadalafil)
Trials
(tadalafil)
Recent Studies (post-2010)
(tadalafil)
Studies
(malondialdehyde)
Trials
(malondialdehyde)
Recent Studies (post-2010) (malondialdehyde)
1,7423921,08927,8491,40513,922

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's19 (86.36)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Güven, EO; Oktar, S; Ozgiray, E; Serarslan, Y; Söğüt, S; Yilmaz, N; Yönden, Z; Yurtseven, T1
Akdag, E; Akyol, M; Haberal, A; Kayir, H; Kucukozkan, T; Oter, S; Ozdegirmenci, O; Topal, T; Uzbay, T1
Arikan, DC; Bakan, V; Coskun, A; Kurutas, EB; Sayar, H1
Fahim, M; Kotwani, A; Rashid, M2
Kotb, K; Mostafa, T; Rashed, L; Taymour, M1
Chen, Y; Dai, YT; Gao, J; Li, XX; Lin, HC; Qiu, XF; Wang, R1
Erkasap, N; Erkasap, S; Koken, T; Küçük, A; Ozkurt, M; Tosun, M; Yucel, M1
Altaş, M; Aras, M; Meydan, S; Nacar, E; Serarslan, Y; Ulutaş, KT; Yılmaz, N1
Aziret, M; Cetinkunar, S; Deger, KC; Demirturk, P; Erdem, H; Irkorucu, O; Ozkara, S; Reyhan, E; Sehirli, AO; Surmelioglu, A1
Baldari, C; Ceci, R; Di Luigi, L; Duranti, G; Guidetti, L; Sabatini, S; Sansone, M; Sgrò, P1
Altunkaş, F; Çelik, A; Ceyhan, K; Kadı, H; Karayakalı, M; Koç, F; Köseoğlu, RD; Önalan, O; Özbek, K; Söğüt, E1
Cai, J; Chen, TK; Li, CD; Wang, GB; Wu, ZG; Xiao, YB1
Akduman, B; Bektas, S; Erol, B; Karakas, B; Mungan, A; Mungan, G; Ozkanli, S; Tok, A; Tokgoz, H; Turker, T1
Nna, VU; Osim, EE1
Abu-Risha, SE; El-Sisi, AE; Ibrahim, HA; Sokar, SS1
Mostafa, RE; Omara, EA; Salama, A1
Bhattacharya, SK; Gulati, K; Gupta, R; Laxmi, V; Ray, A1
Artigiane-Neto, R; Fujiki, RTM; Martins, JL; Mismetti, MM; Montero, EFS; Souza, CM; Souza, CVCP; Teixeira, LC1
Higashi, Y; Kamada, S; Kataoka, T; Nagao, Y; Saito, M; Shimizu, S; Shimizu, T1
Abd Al Haleem, EN; Arafa, HMM; Ibrahim, FAM; Zaytoon, SAB1
Abuawad, Z; Andelova, K; Fulop, M; Kalocayova, B; Kura, B; Sagatova, A; Slezak, J; Sykora, M; Szeiffova Bacova, B1

Trials

1 trial(s) available for tadalafil and malondialdehyde

ArticleYear
Effects of tadalafil administration on plasma markers of exercise-induced muscle damage, IL6 and antioxidant status capacity.
    European journal of applied physiology, 2015, Volume: 115, Issue:3

    Topics: Adult; Antioxidants; Biomarkers; Carbolines; Creatine Kinase; Exercise; Female; Glutathione; Humans; Interleukin-6; L-Lactate Dehydrogenase; Male; Malondialdehyde; Muscle, Skeletal; Myalgia; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Protein Carbonylation; Tadalafil

2015

Other Studies

21 other study(ies) available for tadalafil and malondialdehyde

ArticleYear
Protective effects of tadalafil on experimental spinal cord injury in rats.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Carbolines; Disease Models, Animal; Glutathione; Male; Malondialdehyde; Methylprednisolone; Methylprednisolone Acetate; Motor Activity; Nitric Oxide; Phosphodiesterase Inhibitors; Random Allocation; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries; Superoxide Dismutase; Tadalafil; Treatment Outcome

2010
Effects of sildenafil and tadalafil on ischemia/reperfusion injury in fetal rat brain.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2011, Volume: 24, Issue:2

    Topics: Animals; Brain; Carbolines; Female; Fetus; Glutathione Peroxidase; Malondialdehyde; Piperazines; Pregnancy; Purines; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Sildenafil Citrate; Sulfones; Superoxide Dismutase; Tadalafil; Vasodilator Agents

2011
Protective effect of tadalafil on ischemia/reperfusion injury of rat ovary.
    Journal of pediatric surgery, 2010, Volume: 45, Issue:11

    Topics: Animals; Carbolines; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Lipid Peroxidation; Malondialdehyde; Nitric Oxide; Ovary; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spectrophotometry; Superoxide Dismutase; Tadalafil; Treatment Outcome

2010
Long-acting phosphodiesterase 5 inhibitor, tadalafil, and superoxide dismutase mimetic, tempol, protect against acute hypoxia-induced pulmonary hypertension in rats.
    Human & experimental toxicology, 2012, Volume: 31, Issue:6

    Topics: Animals; Antioxidants; Blood Pressure; Carbolines; Cardiac Output; Cyclic N-Oxides; Heart Rate; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Malondialdehyde; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Rats; Rats, Wistar; Spin Labels; Tadalafil; Vasodilation

2012
Efficacy of tadalafil in chronic hypobaric hypoxia-induced pulmonary hypertension: possible mechanisms.
    Fundamental & clinical pharmacology, 2013, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carbolines; Cyclic N-Oxides; Disease Models, Animal; Glutathione; Hypertension, Pulmonary; Hypoxia; Inflammation; Lung; Malondialdehyde; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Rats; Rats, Wistar; Spin Labels; Superoxide Dismutase; Tadalafil; Tumor Necrosis Factor-alpha; Ventricular Pressure

2013
Effect of testosterone and frequent low-dose sildenafil/tadalafil on cavernous tissue oxidative stress of aged diabetic rats.
    Andrologia, 2012, Volume: 44, Issue:6

    Topics: Aging; Animals; Carbolines; Cyclic GMP; Diabetes Mellitus, Experimental; Erectile Dysfunction; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Penile Erection; Penis; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Tadalafil; Testosterone; Vasodilator Agents

2012
The effects of long-term administration of tadalafil on STZ-induced diabetic rats with erectile dysfunction via a local antioxidative mechanism.
    Asian journal of andrology, 2012, Volume: 14, Issue:4

    Topics: Animals; Antioxidants; Blood Pressure; Carbolines; Diabetes Mellitus, Experimental; Erectile Dysfunction; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria, Muscle; Penis; Phosphodiesterase 5 Inhibitors; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Tadalafil

2012
The effects of PDE5 inhibitory drugs on renal ischemia/reperfusion injury in rats.
    Molecular biology reports, 2012, Volume: 39, Issue:10

    Topics: Animals; Apoptosis; Carbolines; Gene Expression; Ischemia; Kidney; Male; Malondialdehyde; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sildenafil Citrate; Sulfones; Tadalafil; Tumor Suppressor Protein p53

2012
Effects of tadalafil on ischemia/reperfusion injury in rat brain.
    Acta neurologica Belgica, 2014, Volume: 114, Issue:1

    Topics: Analysis of Variance; Animals; Brain Ischemia; Carbolines; Disease Models, Animal; Glutathione Peroxidase; Male; Malondialdehyde; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Tadalafil; Time Factors

2014
Efficacy of pentoxifylline and tadalafil in rat model of ischemic colitis.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2014, Volume: 27, Issue:6

    Topics: Animals; Carbolines; Colitis, Ischemic; Colon; Disease Models, Animal; Female; Laparotomy; Malondialdehyde; Pentoxifylline; Phosphodiesterase 5 Inhibitors; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Tadalafil; Treatment Outcome

2014
The protective effect of single dose tadalafil in contrast-induced nephropathy: an experimental study.
    Anatolian journal of cardiology, 2015, Volume: 15, Issue:4

    Topics: Administration, Oral; Animals; Contrast Media; Dose-Response Relationship, Drug; Female; Malondialdehyde; Phosphodiesterase 5 Inhibitors; Rats; Rats, Wistar; Renal Insufficiency; Tadalafil

2015
[Protective effect of tadalafil against ischemia-reperfusion injury in rats].
    Zhonghua nan ke xue = National journal of andrology, 2015, Volume: 21, Issue:3

    Topics: Animals; Biomarkers; Carbolines; Dose-Response Relationship, Drug; Male; Malondialdehyde; Phosphodiesterase 5 Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Seminiferous Tubules; Spermatic Cord Torsion; Superoxide Dismutase; Tadalafil; Testis; Time Factors

2015
The protective effects of tadalafil on renal damage following ischemia reperfusion injury in rats.
    The Kaohsiung journal of medical sciences, 2015, Volume: 31, Issue:9

    Topics: Animals; Antioxidants; Apoptotic Protease-Activating Factor 1; Immunohistochemistry; Kidney; Kidney Tubules; Malondialdehyde; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protective Agents; Rats, Wistar; Reperfusion Injury; Tadalafil

2015
Testicular toxicity following separate and combined administration of PDE5 inhibitors and opioid: assessment of recovery following their withdrawal.
    Andrologia, 2017, Volume: 49, Issue:6

    Topics: Analgesics, Opioid; Animals; Body Weight; Catalase; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Organ Size; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Rats; Rats, Wistar; Sperm Motility; Superoxide Dismutase; Tadalafil; Testis; Tramadol

2017
Combination of tadalafil and diltiazem attenuates renal ischemia reperfusion-induced acute renal failure in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Acute Kidney Injury; Animals; Apoptosis; Blood Urea Nitrogen; Creatinine; Diltiazem; Drug Therapy, Combination; Intercellular Adhesion Molecule-1; Interleukin-1beta; Kidney; Male; Malondialdehyde; Peroxidase; Rats; Reperfusion Injury; Superoxide Dismutase; Tadalafil; Tumor Necrosis Factor-alpha

2016
Effects of phosphodiestrase type 5 inhibitors in epinephrine-induced arrhythmia in rats: Involvement of lactate dehydrogenase and creatine kinase downregulation and adiponectin expression.
    Human & experimental toxicology, 2018, Volume: 37, Issue:3

    Topics: Adiponectin; Animals; Anti-Arrhythmia Agents; Apoptosis; Arrhythmias, Cardiac; Caspase 3; Creatine Kinase; Disease Models, Animal; Electrocardiography; Epinephrine; Glutathione; Heart Rate; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardium; Necrosis; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Rats, Wistar; Sildenafil Citrate; Tadalafil; Vardenafil Dihydrochloride

2018
Inhibitory effects of sildenafil and tadalafil on inflammation, oxidative stress and nitrosative stress in animal model of bronchial asthma.
    Pharmacological reports : PR, 2019, Volume: 71, Issue:3

    Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Glutathione; Inflammation; Lung; Male; Malondialdehyde; Nitric Oxide; Nitrosative Stress; Oxidative Stress; Rats; Rats, Wistar; Sildenafil Citrate; Tadalafil

2019
Oxidative stress assessment in intestine of newborn rats submitted to hypoxia and reoxygenation with tadalafil.
    Acta cirurgica brasileira, 2019, Apr-29, Volume: 34, Issue:4

    Topics: Animals; Animals, Newborn; Female; Humans; Hypoxia; Intestinal Mucosa; Lipid Peroxidation; Malondialdehyde; Nitrates; Nitrites; Oxidative Stress; Oxygen; Phosphodiesterase 5 Inhibitors; Pregnancy; Random Allocation; Rats, Wistar; Reproducibility of Results; Tadalafil; Time Factors

2019
Protective effects of tadalafil on prostatic hyperplasia in spontaneously hypertensive rats.
    European journal of pharmacology, 2020, Sep-05, Volume: 882

    Topics: Animals; Fibroblast Growth Factors; Hypertension; Interleukin-6; Male; Malondialdehyde; Phosphodiesterase 5 Inhibitors; Prostate; Prostatic Hyperplasia; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Tadalafil; Transforming Growth Factor beta1

2020
Possible protective effect of TNF-α inhibition and triad NO/cGMP/VEGF activation on gastric ulcer in rats.
    Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:9

    Topics: Animals; Cyclic GMP; Dinoprostone; Indomethacin; Male; Malondialdehyde; Nitric Oxide; Pentoxifylline; Rats; Stomach Ulcer; Tadalafil; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2021
The effect of selected drugs on the mitigation of myocardial injury caused by gamma radiation.
    Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:1

    Topics: Animals; Atorvastatin; Cardiomyopathies; Free Radicals; Gamma Rays; Heart; Male; Malondialdehyde; Myocardium; Oxidative Stress; Radiation Injuries, Experimental; Rats; Tadalafil; Treatment Outcome; Tumor Necrosis Factor-alpha

2021