Page last updated: 2024-09-02

tadalafil and lidocaine

tadalafil has been researched along with lidocaine in 4 studies

Compound Research Comparison

Studies (tadalafil)	Trials (tadalafil)	Recent Studies (post-2010) (tadalafil)	Studies (lidocaine)	Trials (lidocaine)	Recent Studies (post-2010) (lidocaine)
1,742	392	1,089	26,090	5,904	5,591

Protein Interaction Comparison

Protein	Taxonomy	tadalafil (IC50)	lidocaine (IC50)
Sodium channel protein type 4 subunit alpha	Homo sapiens (human)		2

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	3 (75.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dell'Atti, L; Galosi, AB; Ippolito, C	1

Reviews

1 review(s) available for tadalafil and lidocaine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for tadalafil and lidocaine

Article	Year
A randomized single-center study to compare the efficacy and tolerability of tadalafil once daily plus lidocaine anesthetic spray on premature ejaculation. European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:5 Topics: Anesthetics, Local; Ejaculation; Humans; Lidocaine; Male; Premature Ejaculation; Tadalafil; Vasodilator Agents	2017

Other Studies

2 other study(ies) available for tadalafil and lidocaine

Article	Year
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation. European journal of medicinal chemistry, 2008, Volume: 43, Issue:11 Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG	2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013

Article

Year

Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.

European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG

2008

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013