tadalafil has been researched along with epalrestat in 1 studies
| Studies (tadalafil) | Trials (tadalafil) | Recent Studies (post-2010) (tadalafil) | Studies (epalrestat) | Trials (epalrestat) | Recent Studies (post-2010) (epalrestat) |
|---|---|---|---|---|---|
| 1,742 | 392 | 1,089 | 243 | 22 | 100 |
| Protein | Taxonomy | tadalafil (IC50) | epalrestat (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 7.9635 | |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 6.5 | |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 0.1836 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.5596 | |
| Aldo-keto reductase family 1 member A1 | Homo sapiens (human) | 2.6 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 0.1335 | |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | 0.17 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.085 | |
| Aldo-keto reductase family 1 member A1 | Sus scrofa (pig) | 1.5 | |
| Aldo-keto reductase family 1 member A1 | Rattus norvegicus (Norway rat) | 1.5 | |
| Aldo-keto reductase family 1 member B7 | Rattus norvegicus (Norway rat) | 1.198 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
1 other study(ies) available for tadalafil and epalrestat
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |