Compounds > tadalafil
Page last updated: 2024-09-02

tadalafil and desloratadine

tadalafil has been researched along with desloratadine in 4 studies

Compound Research Comparison

Studies
(tadalafil)		Trials
(tadalafil)		Recent Studies (post-2010)
(tadalafil)		Studies
(desloratadine)		Trials
(desloratadine)		Recent Studies (post-2010) (desloratadine)
1,7423921,089465146166

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)desloratadine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.03
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.116
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.107
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.339
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.292
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.267
Alpha-2B adrenergic receptorHomo sapiens (human)2.146
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.446
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.116
Histamine H2 receptorHomo sapiens (human)1.099
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.033
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.03
Sodium-dependent serotonin transporterHomo sapiens (human)0.23
Histamine H1 receptorHomo sapiens (human)0.0059
D(3) dopamine receptorHomo sapiens (human)1.906
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.043
5-hydroxytryptamine receptor 6Homo sapiens (human)2.171
Sodium-dependent dopamine transporter Homo sapiens (human)3.879

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adam, V; Markova, K; Mravec, F; Nejdl, L; Pavelicova, K; Rypar, T; Vaculovicova, M1

Reviews

1 review(s) available for tadalafil and desloratadine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for tadalafil and desloratadine

ArticleYear
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
UV-responsive fluorescent behavior of pharmaceuticals assessed by UV-induced fingerprint spectroscopy (UV-IFS).
    International journal of pharmaceutics, 2022, Nov-25, Volume: 628

    Topics: Acetaminophen; Loratadine; Sildenafil Citrate; Spectrum Analysis; Tablets; Tadalafil

2022