tadalafil has been researched along with danazol in 3 studies
| Studies (tadalafil) | Trials (tadalafil) | Recent Studies (post-2010) (tadalafil) | Studies (danazol) | Trials (danazol) | Recent Studies (post-2010) (danazol) |
|---|---|---|---|---|---|
| 1,742 | 392 | 1,089 | 2,402 | 288 | 279 |
| Protein | Taxonomy | tadalafil (IC50) | danazol (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Glucocorticoid receptor | Homo sapiens (human) | 4.314 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.019 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 4.314 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 5.698 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.3 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.012 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 4.314 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 4.314 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 5.698 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 4.314 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 8.85 | |
| Cytochrome P450 2J2 | Homo sapiens (human) | 0.0317 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 6.842 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Amodeo, P; Arroyo, FJ; Bianchini, G; De Petrocellis, L; López-Alvarado, P; Martín, MA; Menéndez, JC; Orlando, P; Roncero, C; Sánchez, A; Schiano Moriello, A; Vitale, RM | 1 |
1 review(s) available for tadalafil and danazol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for tadalafil and danazol
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.
Topics: Animals; Antineoplastic Agents; Calcium; Cell Proliferation; Diketopiperazines; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Prostatic Neoplasms; Structure-Activity Relationship; Tetrahydroisoquinolines; TRPM Cation Channels; Tumor Cells, Cultured; Urea | 2016 |