tadalafil has been researched along with citalopram in 4 studies
| Studies (tadalafil) | Trials (tadalafil) | Recent Studies (post-2010) (tadalafil) | Studies (citalopram) | Trials (citalopram) | Recent Studies (post-2010) (citalopram) |
|---|---|---|---|---|---|
| 1,742 | 392 | 1,089 | 5,348 | 1,424 | 2,350 |
| Protein | Taxonomy | tadalafil (IC50) | citalopram (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.297 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 2.196 | |
| Aromatase | Rattus norvegicus (Norway rat) | 0.0018 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 2.196 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 3.289 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.297 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.0227 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.0027 | |
| Histamine H1 receptor | Homo sapiens (human) | 3.194 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.839 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.1869 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.398 | |
| Transporter | Rattus norvegicus (Norway rat) | 8.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faller, B; Trunzer, M; Zimmerlin, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Abdel-Fattah, A; Abdel-Raoof, AM; Eissa, MS; Hasan, MA; Madkour, AW | 1 |
1 review(s) available for tadalafil and citalopram
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 other study(ies) available for tadalafil and citalopram
| Article | Year |
|---|---|
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.
Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry | 2009 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Simultaneous determination of citalopram and tadalafil by the second derivative synchronous fluorescence method in biological fluids; application of Box-Behnken optimization design.
Topics: Citalopram; Humans; Spectrometry, Fluorescence; Staining and Labeling; Tablets; Tadalafil | 2021 |