Compounds > tadalafil
Page last updated: 2024-09-02

tadalafil and cilomilast

tadalafil has been researched along with cilomilast in 2 studies

Compound Research Comparison

Studies
(tadalafil)		Trials
(tadalafil)		Recent Studies (post-2010)
(tadalafil)		Studies
(cilomilast)		Trials
(cilomilast)		Recent Studies (post-2010) (cilomilast)
1,7423921,0891621342

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)cilomilast (IC50)
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.018
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.018
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.3453
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)2.3453
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.3453
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Rattus norvegicus (Norway rat)0.113
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicus (Norway rat)0.113
cAMP-specific 3',5'-cyclic phosphodiesterase 4BRattus norvegicus (Norway rat)0.1623
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)0.3113
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.062
cAMP-specific 3',5'-cyclic phosphodiesterase 4ARattus norvegicus (Norway rat)0.113
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)2.3453
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.4623
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)0.818
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.4642
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)4.259
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)10
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.12
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)2.3453
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)2.3453
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)2.3453

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artis, DR; Bollag, G; Card, GL; England, BP; Fong, D; Gillette, S; Ibrahim, PN; Kim, SH; Lee, B; Luu, C; Milburn, MV; Powell, B; Schlessinger, J; Suzuki, Y; Tabrizizad, M; Zhang, KY1
Hughes, RA; Manallack, DT; Thompson, PE1

Reviews

1 review(s) available for tadalafil and cilomilast

ArticleYear
The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.
    Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10

    Topics: Animals; Binding Sites; Crystallography, X-Ray; Cyclic AMP; Cyclic GMP; Drug Design; Humans; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Quantitative Structure-Activity Relationship; Xanthines

2005

Other Studies

1 other study(ies) available for tadalafil and cilomilast

ArticleYear
Structural basis for the activity of drugs that inhibit phosphodiesterases.
    Structure (London, England : 1993), 2004, Volume: 12, Issue:12

    Topics: Binding Sites; Crystallography, X-Ray; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Structure, Tertiary

2004