Page last updated: 2024-09-02

tadalafil and cifenline

tadalafil has been researched along with cifenline in 2 studies

Compound Research Comparison

Studies
(tadalafil)
Trials
(tadalafil)
Recent Studies (post-2010)
(tadalafil)
Studies
(cifenline)
Trials
(cifenline)
Recent Studies (post-2010) (cifenline)
1,7423921,0893034933

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)cifenline (IC50)
Sodium channel protein type 1 subunit alphaHomo sapiens (human)7.8
Sodium channel protein type 4 subunit alphaHomo sapiens (human)7.8
Sodium channel protein type 7 subunit alphaHomo sapiens (human)7.8
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)8.8
Sodium channel protein type 5 subunit alphaHomo sapiens (human)7.8
Sodium channel protein type 9 subunit alphaHomo sapiens (human)7.8
Sodium channel protein type 2 subunit alphaHomo sapiens (human)7.8
Sodium channel protein type 3 subunit alphaHomo sapiens (human)7.8
Sodium channel protein type 11 subunit alphaHomo sapiens (human)7.8
Sodium channel protein type 8 subunit alphaHomo sapiens (human)7.8
Sodium channel protein type 10 subunit alphaHomo sapiens (human)7.8

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faller, B; Trunzer, M; Zimmerlin, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Other Studies

2 other study(ies) available for tadalafil and cifenline

ArticleYear
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.
    Journal of medicinal chemistry, 2009, Jan-22, Volume: 52, Issue:2

    Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry

2009
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013