tadalafil has been researched along with carbachol in 3 studies
| Studies (tadalafil) | Trials (tadalafil) | Recent Studies (post-2010) (tadalafil) | Studies (carbachol) | Trials (carbachol) | Recent Studies (post-2010) (carbachol) |
|---|---|---|---|---|---|
| 1,742 | 392 | 1,089 | 13,918 | 81 | 968 |
| Protein | Taxonomy | tadalafil (IC50) | carbachol (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.7849 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.0626 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.4134 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.535 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.6638 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.849 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 4.99 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Antunes, E; Baracat, JS; Claudino, MA; De Nucci, G; Priviero, FB; Teixeira, CE; Webb, RC | 1 |
| Alexandre, L; Behr-Roussel, D; Denoux, Y; Giuliano, F; Gorny, D; Lebret, T; Oger, S | 1 |
| Fujimoto, K; Gotoh, D; Hirayama, A; Hori, S; Iwamoto, T; Iwasaki, H; Miyake, M; Morizawa, Y; Nishi, E; Tanaka, N; Torimoto, K | 1 |
3 other study(ies) available for tadalafil and carbachol
| Article | Year |
|---|---|
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide.
Topics: Animals; Carbachol; Carbolines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Tadalafil; Tetrodotoxin | 2006 |
Combination of alfuzosin and tadalafil exerts an additive relaxant effect on human detrusor and prostatic tissues in vitro.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Aged; Carbachol; Carbolines; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electric Stimulation; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Phosphodiesterase 5 Inhibitors; Prostate; Quinazolines; Tadalafil; Urinary Bladder | 2010 |
Tadalafil, a phosphodiesterase type 5 inhibitor, restores urethra and detrusor function in the initial phase of diabetes in rats.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Electric Stimulation; Female; Muscle Contraction; Muscle, Smooth; Phosphodiesterase 5 Inhibitors; Rats; Rats, Sprague-Dawley; Tadalafil; Urethra; Urinary Bladder | 2019 |