tadalafil has been researched along with avanafil in 12 studies
| Studies (tadalafil) | Trials (tadalafil) | Recent Studies (post-2010) (tadalafil) | Studies (avanafil) | Trials (avanafil) | Recent Studies (post-2010) (avanafil) |
|---|---|---|---|---|---|
| 1,742 | 392 | 1,089 | 68 | 14 | 63 |
| Protein | Taxonomy | tadalafil (IC50) | avanafil (IC50) |
|---|---|---|---|
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 5.2 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Canis lupus familiaris (dog) | 0.0052 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (91.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fujishige, K; Hikota, M; Kikkawa, K; Koga, Y; Kotera, J; Matsuki, K; Morimoto, H; Murakami, M; Omori, K; Sakamoto, T; Yamada, K | 1 |
| Cheng, C; Jiang, Y; Lou, H; Qiao, Y; Sun, B; Tan, J; Wu, Y; Xie, Z; Zhao, S; Zheng, H | 1 |
| Fujishige, K; Inoue, H; Kikkawa, K; Kobayashi, T; Kojima, K; Kotera, J; Mochida, H; Noto, T; Omori, K; Sasaki, T; Yamada, Y; Yee, S | 1 |
| Burnett, AL; Day, WW; DiDonato, K; Heller, WH; Kikkawa, K; Kotera, J; Omori, K; Peterson, CA; Wang, R; Yee, S | 1 |
| Callahan, RJ; Dunn, JD; Gryniewicz-Ruzicka, CM; Mans, DJ | 1 |
| Chandra, S; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Lasker, GF; Pankey, EA; Sikka, SC | 1 |
| Cui, Y; Gao, Z; Liu, X; Shi, L | 1 |
| Li, AS; Pomeranz, HD | 1 |
| Bajorath, J; Kunimoto, R | 1 |
| Bakırdere, S; Özbek, B; Öztürk Er, E | 1 |
| Abdel-Raoof, AM; Abdelzaher, AM; El-Desouky, EA; Emara, MS; Hasan, MA; Osman, AE; Said, RAM | 1 |
1 review(s) available for tadalafil and avanafil
| Article | Year |
|---|---|
Efficacy and safety of phosphodiesterase type 5 (PDE5) inhibitors in treating erectile dysfunction after bilateral nerve-sparing radical prostatectomy.
Topics: Erectile Dysfunction; Humans; Male; Organ Sparing Treatments; Peripheral Nerves; Phosphodiesterase 5 Inhibitors; Postoperative Complications; Prostatectomy; Pyrimidines; Sildenafil Citrate; Tadalafil; Treatment Outcome; Vardenafil Dihydrochloride | 2016 |
11 other study(ies) available for tadalafil and avanafil
| Article | Year |
|---|---|
The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor.
Topics: Animals; Erectile Dysfunction; Humans; Male; Phosphodiesterase 5 Inhibitors; Pyrimidines; Rabbits | 2014 |
Discovery of furyl/thienyl β-carboline derivatives as potent and selective PDE5 inhibitors with excellent vasorelaxant effect.
Topics: Animals; Carbolines; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Design; Female; Humans; Male; Mesenteric Arteries; Molecular Docking Simulation; Phosphodiesterase 5 Inhibitors; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents | 2018 |
Avanafil, a potent and highly selective phosphodiesterase-5 inhibitor for erectile dysfunction.
Topics: Animals; Carbolines; Dogs; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Imidazoles; Infusions, Intravenous; Male; Penile Erection; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Pyrimidines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride | 2012 |
Selectivity of avanafil, a PDE5 inhibitor for the treatment of erectile dysfunction: implications for clinical safety and improved tolerability.
Topics: Carbolines; Erectile Dysfunction; Humans; Imidazoles; Male; Penile Erection; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Pyrimidines; Randomized Controlled Trials as Topic; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride | 2012 |
Rapid-screening detection of acetildenafils, sildenafils and avanafil by ion mobility spectrometry.
Topics: Carbolines; Chemistry Techniques, Analytical; Dietary Supplements; Food Contamination; Food Inspection; Imidazoles; Isomerism; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Pyrimidines; Sildenafil Citrate; Sulfones; Tadalafil; Tandem Mass Spectrometry; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents | 2013 |
Erectile dysfunction and the drugs to treat it. In many cases, medications are all a man needs to stay sexually active.
Topics: Aged; Carbolines; Erectile Dysfunction; Humans; Imidazoles; Life Style; Male; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Pyrimidines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride | 2014 |
Effect of avanafil on rat and human corpus cavernosum.
Topics: Animals; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Male; Penis; Phosphodiesterase 5 Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Tadalafil; Vasodilation | 2015 |
Food and Drug Administration Adverse Event Reports of Retinal Vascular Occlusions Associated With Phosphodiesterase Type 5 Inhibitor Use.
Topics: Adverse Drug Reaction Reporting Systems; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Phosphodiesterase 5 Inhibitors; Product Surveillance, Postmarketing; Pyrimidines; Retinal Artery Occlusion; Retinal Vein Occlusion; Sildenafil Citrate; Tadalafil; United States; United States Food and Drug Administration; Vardenafil Dihydrochloride | 2016 |
Exploring sets of molecules from patents and relationships to other active compounds in chemical space networks.
Topics: Chemistry, Pharmaceutical; Data Mining; Drug Discovery; Humans; Medroxyprogesterone; Molecular Structure; Patents as Topic; Pharmaceutical Preparations; Pyrimidines; Small Molecule Libraries; Structure-Activity Relationship; Tadalafil; Toremifene | 2017 |
Accurate and sensitive determination of sildenafil, tadalafil, vardenafil, and avanafil in illicit erectile dysfunction medications and human urine by LC with quadrupole-TOF-MS/MS and their behaviors in simulated gastric conditions.
Topics: Chromatography, Liquid; Erectile Dysfunction; Humans; Illicit Drugs; Male; Pyrimidines; Sildenafil Citrate; Stomach; Tadalafil; Tandem Mass Spectrometry; Vardenafil Dihydrochloride | 2019 |
D-optimal design as a useful tool response surface methodology for the optimization of signals from synchronous fluorescence prior to simultaneous determination of avanafil and tadalafil.
Topics: Chemistry, Pharmaceutical; Cyclic Nucleotide Phosphodiesterases, Type 5; Fluorescence; Humans; Linear Models; Plasma; Pyrimidines; Reproducibility of Results; Spectrometry, Fluorescence; Tablets; Tadalafil | 2020 |