tadalafil has been researched along with atorvastatin in 5 studies
| Studies (tadalafil) | Trials (tadalafil) | Recent Studies (post-2010) (tadalafil) | Studies (atorvastatin) | Trials (atorvastatin) | Recent Studies (post-2010) (atorvastatin) |
|---|---|---|---|---|---|
| 1,742 | 392 | 1,089 | 7,420 | 2,058 | 3,782 |
| Protein | Taxonomy | tadalafil (IC50) | atorvastatin (IC50) |
|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0064 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.0002 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0002 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0054 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 4.3 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gokce, Mİ; Güleç, S; Gülpınar, Ö; Öztürk, E; Yaman, Ö | 1 |
| Abuawad, Z; Andelova, K; Fulop, M; Kalocayova, B; Kura, B; Sagatova, A; Slezak, J; Sykora, M; Szeiffova Bacova, B | 1 |
1 review(s) available for tadalafil and atorvastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for tadalafil and atorvastatin
| Article | Year |
|---|---|
Effect of atorvastatin on erectile functions in comparison with regular tadalafil use. A prospective single-blind study.
Topics: Adult; Aged; Atorvastatin; Carbolines; Erectile Dysfunction; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Penile Erection; Phosphodiesterase 5 Inhibitors; Pyrroles; Single-Blind Method; Tadalafil | 2012 |
3 other study(ies) available for tadalafil and atorvastatin
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
The effect of selected drugs on the mitigation of myocardial injury caused by gamma radiation.
Topics: Animals; Atorvastatin; Cardiomyopathies; Free Radicals; Gamma Rays; Heart; Male; Malondialdehyde; Myocardium; Oxidative Stress; Radiation Injuries, Experimental; Rats; Tadalafil; Treatment Outcome; Tumor Necrosis Factor-alpha | 2021 |