Page last updated: 2024-09-02

tadalafil and alprostadil

tadalafil has been researched along with alprostadil in 14 studies

Compound Research Comparison

Studies
(tadalafil)
Trials
(tadalafil)
Recent Studies (post-2010)
(tadalafil)
Studies
(alprostadil)
Trials
(alprostadil)
Recent Studies (post-2010) (alprostadil)
1,7423921,0897,136864761

Protein Interaction Comparison

ProteinTaxonomytadalafil (IC50)alprostadil (IC50)
Multidrug resistance-associated protein 4Homo sapiens (human)2.3
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.0358

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (50.00)29.6817
2010's6 (42.86)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Cestari, A; Deho', F; Guazzoni, G; Montorsi, F; Rigatti, P; Salonia, A; Stief, C1
Gaines, KK1
Hatzichristou, DG; Hatzimouratidis, K1
Agarwal, A; Nandipati, KC; Raina, R; Zippe, CD1
Gopalakrishanan, G; Tharyan, P1
Calogero, AE; Cannizzaro, MA; Condorelli, R; La Vignera, S; Noto, Z; Vicari, E1
Katz, A1
Eisenhardt, SU; Fritsche, HM; Iblher, N; Katzenwadel, A; Lampert, F; Penna, V; Stark, GB1
Barret, E; Cathala, N; Cathelineau, X; Djavan, B; Galiano, M; Giuliano, F; Jaffe, J; Kazzazi, A; Mombet, A; Prapotnich, D; Rozet, F; Sanchez-Salas, R; Vallancien, G1
Brock, G; Burnett, A; Ghanem, H; Giuliano, F; Glina, S; Hellstrom, W; Martin-Morales, A; Porst, H; Salonia, A; Sharlip, I1
Giessing, M; Neumann, NJ; Thierling, U; Uche-Holub, E1
Comerma-Steffensen, S; Knudsen, JS; Munk, NE; Simonsen, U1
Forootanfar, H; Hamzehnejadi, M; Homayouni, F; Jahani, Z; Langarizadeh, MA; Rezaei, M; Tavakoli, MR1

Reviews

8 review(s) available for tadalafil and alprostadil

ArticleYear
Pharmacological management of erectile dysfunction.
    BJU international, 2003, Volume: 91, Issue:5

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Carbolines; Drug Combinations; Erectile Dysfunction; Humans; Imidazoles; Injections; Male; Papaverine; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents

2003
A comparative review of the options for treatment of erectile dysfunction: which treatment for which patient?
    Drugs, 2005, Volume: 65, Issue:12

    Topics: Administration, Oral; Alprostadil; Apomorphine; Carbolines; Constriction; Contraindications; Dopamine Agonists; Drug Combinations; Enzyme Inhibitors; Erectile Dysfunction; Humans; Imidazoles; Male; Papaverine; Patient Satisfaction; Penile Prosthesis; Penis; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Regional Blood Flow; Sildenafil Citrate; Sulfones; Tadalafil; Treatment Failure; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents

2005
Erectile dysfunction following radical retropubic prostatectomy: epidemiology, pathophysiology and pharmacological management.
    Drugs & aging, 2006, Volume: 23, Issue:2

    Topics: Administration, Oral; Aged; Algorithms; Alprostadil; Carbolines; Combined Modality Therapy; Drug Therapy, Combination; Erectile Dysfunction; Humans; Imidazoles; Male; Middle Aged; Penile Prosthesis; Phosphodiesterase Inhibitors; Piperazines; Practice Guidelines as Topic; Prostatectomy; Purines; Randomized Controlled Trials as Topic; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents

2006
Erectile dysfunction.
    Clinical evidence, 2006, Issue:15

    Topics: Adult; Alprostadil; Apomorphine; Carbolines; Erectile Dysfunction; Humans; Imidazoles; Male; Penile Erection; Penile Prosthesis; Piperazines; Purines; Sex Counseling; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Yohimbine

2006
Penile rehabilitation.
    The American journal of nursing, 2009, Volume: 109, Issue:9

    Topics: Alprostadil; Carbolines; Causality; Clinical Protocols; Erectile Dysfunction; Fibrosis; Humans; Male; Nurse's Role; Penile Prosthesis; Penis; Phosphodiesterase Inhibitors; Piperazines; Postoperative Care; Prostatectomy; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Time Factors; Vasodilator Agents

2009
SOP conservative (medical and mechanical) treatment of erectile dysfunction.
    The journal of sexual medicine, 2013, Volume: 10, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alprostadil; Carbolines; Drug Therapy, Combination; Erectile Dysfunction; Humans; Hypogonadism; Imidazoles; Male; Middle Aged; Penile Erection; Phosphodiesterase 5 Inhibitors; Piperazines; Pyrimidines; Risk Factors; Sulfonamides; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Yohimbine

2013
Systematic Review of Oral Combination Therapy for Erectile Dysfunction When Phosphodiesterase Type 5 Inhibitor Monotherapy Fails.
    Sexual medicine reviews, 2019, Volume: 7, Issue:3

    Topics: Administration, Oral; Alprostadil; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Penile Erection; Phosphodiesterase 5 Inhibitors; Sildenafil Citrate; Tadalafil; Treatment Failure; Treatment Outcome; Vasodilator Agents

2019
Prostaglandins as a Topical Therapy for Erectile Dysfunction: A Comprehensive Review.
    Sexual medicine reviews, 2022, Volume: 10, Issue:4

    Topics: Alprostadil; Cyclic Nucleotide Phosphodiesterases, Type 5; Erectile Dysfunction; Humans; Male; Prostaglandins; Sildenafil Citrate; Tadalafil; Vardenafil Dihydrochloride

2022

Trials

2 trial(s) available for tadalafil and alprostadil

ArticleYear
Tadalafil and modifications in peak systolic velocity (Doppler spectrum dynamic analysis) in the cavernosal arteries of patients with type 2 diabetes after continuous tadalafil treatment.
    Minerva endocrinologica, 2006, Volume: 31, Issue:4

    Topics: Aged; Alprostadil; Arteries; Attitude to Health; Blood Flow Velocity; Carbolines; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Administration Schedule; Erectile Dysfunction; Humans; Injections; Luteinizing Hormone; Male; Middle Aged; Nitric Oxide; Penis; Prolactin; Surveys and Questionnaires; Tadalafil; Testosterone; Treatment Outcome; Vasodilator Agents

2006
Evaluation of erectile function after laparoscopic radical prostatectomy in a single center.
    The Canadian journal of urology, 2012, Volume: 19, Issue:4

    Topics: Adult; Aged; Alprostadil; Carbolines; Coitus; Erectile Dysfunction; Humans; Laparoscopy; Male; Medication Adherence; Middle Aged; Organ Sparing Treatments; Orgasm; Penile Erection; Peripheral Nerves; Phosphodiesterase 5 Inhibitors; Postoperative Care; Prostate; Prostatectomy; Prostatic Neoplasms; Severity of Illness Index; Surveys and Questionnaires; Tadalafil; Vasodilator Agents

2012

Other Studies

4 other study(ies) available for tadalafil and alprostadil

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Coming attractions! New medications on the horizon for erectile dysfunction.
    Urologic nursing, 2003, Volume: 23, Issue:4

    Topics: Alprostadil; Apomorphine; Carbolines; Drug Approval; Erectile Dysfunction; Genetic Therapy; Global Health; Humans; Male; Phosphodiesterase Inhibitors; Tadalafil; United States; United States Food and Drug Administration

2003
Refinements in reconstruction of penile skin loss using intra-operative prostaglandin injections, postoperative tadalafil application and negative pressure dressings.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2012, Volume: 65, Issue:10

    Topics: Adult; Aged; Alprostadil; Carbolines; Fournier Gangrene; Graft Rejection; Graft Survival; Humans; Injections, Intralesional; Intraoperative Care; Male; Negative-Pressure Wound Therapy; Penile Erection; Penis; Plastic Surgery Procedures; Postoperative Care; Recovery of Function; Risk Assessment; Sampling Studies; Skin Transplantation; Tadalafil; Vasodilator Agents; Wound Healing

2012
[Intracavernous injection: a treatment modality for erectile dysfunction].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2013, Volume: 64, Issue:4

    Topics: Alprostadil; Carbolines; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Penis; Piperazines; Purines; Self Administration; Sildenafil Citrate; Sulfones; Tadalafil; Treatment Outcome; Vasodilator Agents

2013