tadalafil has been researched along with alpha-aminopyridine in 4 studies
| Studies (tadalafil) | Trials (tadalafil) | Recent Studies (post-2010) (tadalafil) | Studies (alpha-aminopyridine) | Trials (alpha-aminopyridine) | Recent Studies (post-2010) (alpha-aminopyridine) |
|---|---|---|---|---|---|
| 1,742 | 392 | 1,089 | 5,813 | 460 | 3,246 |
| Protein | Taxonomy | tadalafil (IC50) | alpha-aminopyridine (IC50) |
|---|---|---|---|
| Botulinum neurotoxin type A | Clostridium botulinum | 1.8 | |
| Nitric oxide synthase, endothelial | Homo sapiens (human) | 2.8 | |
| Nitric oxide synthase, brain | Homo sapiens (human) | 6 | |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | 9 | |
| Nitric oxide synthase, inducible | Homo sapiens (human) | 1.9 | |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | 7.1 | |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | 7.1 | |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | 7.1 | |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | 7.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kertys, M; Kosutova, P; Medvedova, I; Mikolka, P; Mokra, D; Mokry, J; Urbanova, A | 1 |
| Kertys, M; Mokry, J; Urbanova, A | 1 |
| Akhtar, M; Hasan, N; Najmi, AK; Parvez, S; Yar, MS; Zameer, S | 1 |
| Agis-Torres, Á; Barahona, MV; Benedito, S; Climent, B; Fernandes, VS; Hernández, M; López-Oliva, ME; Martínez, MP; Navarro-Dorado, J; Prieto, D; Recio, P | 1 |
4 other study(ies) available for tadalafil and alpha-aminopyridine
| Article | Year |
|---|---|
Effects of tadalafil (PDE5 inhibitor) and roflumilast (PDE4 inhibitor) on airway reactivity and markers of inflammation in ovalbumin-induced airway hyperresponsiveness in guinea pigs.
Topics: Aminopyridines; Animals; Benzamides; Biomarkers; Cyclopropanes; Guinea Pigs; Inflammation Mediators; Lung; Male; Organ Culture Techniques; Ovalbumin; Phosphodiesterase 4 Inhibitors; Phosphodiesterase 5 Inhibitors; Random Allocation; Respiratory Hypersensitivity; Tadalafil; Treatment Outcome | 2017 |
Determination of Phosphodiesterase Inhibitors Tadalafil, Roflumilast and Roflumilast N-Oxide Using LC-MS in Guinea Pig Plasma.
Topics: Aminopyridines; Animals; Benzamides; Chromatography, High Pressure Liquid; Cyclopropanes; Guinea Pigs; Linear Models; Male; Phosphodiesterase Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Tadalafil; Tandem Mass Spectrometry | 2018 |
Roflumilast and tadalafil improve learning and memory deficits in intracerebroventricular Aβ1-42 rat model of Alzheimer's disease through modulations of hippocampal cAMP/cGMP/BDNF signaling pathway.
Topics: Alzheimer Disease; Aminopyridines; Amyloid beta-Peptides; Animals; Benzamides; Brain-Derived Neurotrophic Factor; Cyclic AMP; Cyclic GMP; Cyclopropanes; Cytokines; Gene Expression Regulation; Hippocampus; Male; Memory Disorders; Morris Water Maze Test; Oxidative Stress; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Tadalafil; Vasodilator Agents | 2021 |
In vitro inhibition of phosphodiesterase type 4 enhances rat corpus cavernosum nerve-mediated relaxation induced by gasotransmitters.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Animals; Benzamides; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Dose-Response Relationship, Drug; Gasotransmitters; Hydrogen Sulfide; Male; Muscle Relaxation; Nitroarginine; Penis; Peripheral Nerves; Rats, Wistar; Tadalafil | 2022 |