tacrolimus has been researched along with fucoxanthin* in 1 studies
1 other study(ies) available for tacrolimus and fucoxanthin
Article | Year |
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Fucoxanthin Ameliorates Atopic Dermatitis Symptoms by Regulating Keratinocytes and Regulatory Innate Lymphoid Cells.
Fucoxanthin (FX) is a xanthophyll that is contained abundantly in marine plants. The biological action of FX includes its antioxidant and anti-lipogenic activities, while the precise action of its mechanisms on skin cells has not yet been clarified. The current study examined the effect of FX in comparison with tacrolimus (TAC) on NC/Nga mice, which are an atopic dermatitis (AD) model. FX topical treatment dramatically ameliorated itching behavior over the TAC treatment, which was insufficient for improvement of AD symptoms. In Nc/Nga mice, FX or TAC applied to the skin inhibited eosinophil infiltration with decreased expression of Il-33. FX also stimulated Il-2, Il-5, Il-13, Il-10, and TGF-β expression levels, and Sca1 Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Dermatitis, Atopic; Immunity, Innate; Keratinocytes; Lymphocytes; Mice; Tacrolimus; Xanthophylls | 2020 |