tacrine-hydrochloride has been researched along with tetramethylpyrazine* in 1 studies
1 other study(ies) available for tacrine-hydrochloride and tetramethylpyrazine
| Article | Year |
|---|---|
Synthesis and activity towards Alzheimer's disease in vitro: Tacrine, phenolic acid and ligustrazine hybrids.
A series of novel tacrine-phenolic acid dihybrids and tacrine-phenolic acid-ligustrazine trihybrids were synthesized, characterized and screened as novel potential anti-Alzheimer drug candidates. These compounds showed potent inhibition activity towards cholinesterases (ChEs), among of them, 9i was the most potent one towards acetylcholinesterase (eeAChE, IC Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cholinesterase Inhibitors; Humans; Hydroxybenzoates; Models, Molecular; PC12 Cells; Pyrazines; Rats; Tacrine | 2018 |