tacrine and torpedo

tacrine has been researched along with torpedo in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (40.00)	18.2507
2000's	8 (32.00)	29.6817
2010's	7 (28.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Berman, HA; Leonard, K	1
Cantí, C; Marsal, J; Martí, E; Solsona, C	1
Harel, M; Silman, I; Sussman, JL	1
Axelsen, PH; Bouet, F; Ehret-Sabatier, L; Goeldner, M; Harel, M; Hirth, C; Schalk, I; Silman, I; Sussman, JL	1
Carroll, RT; Emmerling, MR; Grimm, JL; Hepburn, TW	1
Antosiewicz, J; Briggs, JM; Gilson, MK; Humblet, C; McCammon, JA; Straatsma, TP; Sussman, JL; Wlodek, ST	1
Capone, F; Colella, A; Gatta, F; Marta, M; Oliverio, A; Patamia, M; Pavone, F; Pomponi, M; Sacchi, S	1
Bodas, E; Cantí, C; Marsal, J; Solsona, C	1
Badia, A; Barril, X; Camps, P; El Achab, R; Eladi Baños, J; Görbig, DM; Luque, FJ; Morral, J; Muñoz-Torrero, D; Orozco, M; Vivas, NM	1
Barril, X; Luque, FJ; Orozco, M	1
Andrisano, V; Belluti, F; Bisi, A; Cavalli, A; Cavrini, V; Gobbi, S; Rampa, A; Recanatini, M; Valenti, P	1
Aleu, J; Cantí, C; Gomez de Aranda, I; Marsal, J; Pang, YP; Ros, E; Solsona, C	1
Bentley, PD; Doucet-Personeni, C; Fletcher, RJ; Greenblatt, HM; Kinkaid, A; Kryger, G; Lewis, T; Pirard, B; Silman, I; Sussman, JL; Taylor, A; Taylor, J; Taylor, R; Viner, R	1
Barril, X; Camps, P; Dvir, H; Harel, M; Luque, FJ; Muñoz-Torrero, D; Orozco, M; Rosenberry, TL; Silman, I; Sussman, JL; Wong, DM	1
Bencharit, S; Danks, MK; Hyatt, JL; Kuhn, P; Morton, CL; Potter, PM; Redinbo, MR	1
Ivorra, I; Morales, A; Olivera-Bravo, S	1
Brumshtein, B; Carlier, PR; Greenblatt, HM; Pang, YP; Rydberg, EH; Shaya, D; Silman, I; Sussman, JL; Williams, LD; Wong, DM	1
Ashani, Y; Konstantinovskii, L; Roth, E; Shnyrov, VL; Silman, I; Weiner, L	1
Cai, Y; Gao, Q; Hei, T; Zhang, Q; Zhang, Y	1
Hao, GF; Yang, GF; Yang, WC; Yu, NX; Zhu, XL	1
Andrisano, V; Bartolini, M; Chen, L; De Simone, A; Egea, J; Kang, D; Lamba, D; Lopez, MG; Lou, Y; Pesaresi, A; Samez, S; Stojan, J; Xu, C; Xu, Y; Zha, X; Zhang, L	1
Almeida, WP; Figueiro, M; Kawano, DF; Sakata, RP	1
Alvim Guedes, I; Antonio Ceschi, M; da Costa Franarin, G; de Salles, CMC; Emmanuel Dardenne, L; Ferreira Dantas, R; Lopes, JPB; Paes Silva-Jr, F; Roberto Senger, M; Seibert Lüdtke, D; Silva, L	1
Akbarzadeh, T; Edraki, N; Karimpour-Razkenari, E; Khanavi, M; Mahdavi, M; Najafi, Z; Saeedi, M; Sharifzadeh, M	1
Fereidoonnezhad, M; Manouchehrizadeh, E; Mostoufi, A; Tahanpesar, E	1

Other Studies

25 other study(ies) available for tacrine and torpedo

Article	Year
Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase. Molecular pharmacology, 1992, Volume: 41, Issue:2 Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Hydrolysis; Kinetics; Tacrine; Torpedo	1992
Tacrine-induced increase in the release of spontaneous high quantal content events in Torpedo electric organ. British journal of pharmacology, 1994, Volume: 112, Issue:1 Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Electric Organ; Electrophysiology; In Vitro Techniques; Kinetics; Membrane Potentials; Microelectrodes; Motor Endplate; Nerve Endings; Physostigmine; Synaptosomes; Tacrine; Torpedo	1994
Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs. Chemico-biological interactions, 1993, Volume: 87, Issue:1-3 Topics: Acetylcholinesterase; Animals; Binding Sites; Edrophonium; Protein Conformation; Tacrine; Torpedo; X-Ray Diffraction	1993
Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proceedings of the National Academy of Sciences of the United States of America, 1993, Oct-01, Volume: 90, Issue:19 Topics: Acetylcholine; Acetylcholinesterase; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Decamethonium Compounds; Edrophonium; Hydrogen Bonding; Ligands; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Quaternary Ammonium Compounds; Tacrine; Torpedo	1993
Purification of acetylcholinesterase by tacrine affinity chromatography. Protein expression and purification, 1995, Volume: 6, Issue:4 Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Cattle; Chromatography, Affinity; Eels; Electric Organ; Molecular Sequence Data; Molecular Weight; Protein Conformation; Resins, Synthetic; Tacrine; Torpedo	1995
Binding of tacrine and 6-chlorotacrine by acetylcholinesterase. Biopolymers, 1996, Volume: 38, Issue:1 Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Models, Chemical; Molecular Structure; Protein Binding; Tacrine; Thermodynamics; Torpedo	1996
Studies on a new series of THA analogues: effects of the aromatic residues that line the gorge of AChE. FEBS letters, 1997, Jun-09, Volume: 409, Issue:2 Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Crystallography, X-Ray; Electrophorus; Kinetics; Models, Molecular; Protein Conformation; Tacrine; Torpedo	1997
Tacrine and physostigmine block nicotinic receptors in Xenopus oocytes injected with Torpedo electroplaque membranes. European journal of pharmacology, 1998, Dec-18, Volume: 363, Issue:2-3 Topics: Animals; Cell Membrane; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Nicotinic Antagonists; Oocytes; Physostigmine; Receptors, Nicotinic; Tacrine; Torpedo; Xenopus	1998
Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease. Journal of medicinal chemistry, 1999, Aug-26, Volume: 42, Issue:17 Topics: Acetylcholinesterase; Alkaloids; Animals; Binding Sites; Cholinesterase Inhibitors; Diaphragm; In Vitro Techniques; Male; Models, Molecular; Muscle Contraction; Neuromuscular Junction; Neuroprotective Agents; Phrenic Nerve; Quinolines; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship; Tacrine; Torpedo	1999
Predicting relative binding free energies of tacrine-huperzine A hybrids as inhibitors of acetylcholinesterase. Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25 Topics: Acetylcholinesterase; Alkaloids; Amino Acid Substitution; Animals; Cholinesterase Inhibitors; Neuroprotective Agents; Protein Binding; Sesquiterpenes; Tacrine; Thermodynamics; Torpedo	1999
Acetylcholinesterase inhibitors for potential use in Alzheimer's disease: molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1,2-b]-quinolin-10-ylamine derivatives. Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:3 Topics: Acetylcholinesterase; Alzheimer Disease; Aminoquinolines; Animals; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computer Simulation; Electrons; Indenes; Inhibitory Concentration 50; Kinetics; Ligands; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tacrine; Torpedo	2000
Effects of bis(7)-tacrine on spontaneous synaptic activity and on the nicotinic ACh receptor of Torpedo electric organ. Journal of neurophysiology, 2001, Volume: 86, Issue:1 Topics: Animals; Bungarotoxins; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electric Organ; Female; Iodine Radioisotopes; Membrane Potentials; Membrane Proteins; Oocytes; Receptors, Nicotinic; Solubility; Synaptic Transmission; Tacrine; Torpedo; Xenopus laevis	2001
A structure-based design approach to the development of novel, reversible AChE inhibitors. Journal of medicinal chemistry, 2001, Sep-27, Volume: 44, Issue:20 Topics: Acetophenones; Acetylcholinesterase; Aminoquinolines; Animals; Binding Sites; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; Models, Molecular; Structure-Activity Relationship; Tacrine; Torpedo	2001
3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates. Biochemistry, 2002, Mar-05, Volume: 41, Issue:9 Topics: Acetylcholinesterase; Alkaloids; Aminoquinolines; Animals; Binding Sites; Chlorine; Cholinesterase Inhibitors; Computer Simulation; Crystallization; Crystallography, X-Ray; Heterocyclic Compounds, 4 or More Rings; Kinetics; Ligands; Models, Molecular; Protein Conformation; Sesquiterpenes; Species Specificity; Tacrine; Torpedo	2002
Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition. Chemistry & biology, 2003, Volume: 10, Issue:4 Topics: Acetylcholinesterase; Animals; Binding Sites; Carboxylesterase; Catalysis; Crystallography, X-Ray; Electrons; Enzyme Inhibitors; Humans; Models, Molecular; Protein Binding; Protein Conformation; Tacrine; Torpedo	2003
The acetylcholinesterase inhibitor BW284c51 is a potent blocker of Torpedo nicotinic AchRs incorporated into the Xenopus oocyte membrane. British journal of pharmacology, 2005, Volume: 144, Issue:1 Topics: Acetylcholine; Animals; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide; Carbachol; Cell Membrane; Cholinergic Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; Female; Inhibitory Concentration 50; Kinetics; Membrane Proteins; Microinjections; Molecular Structure; Neurotransmitter Agents; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Receptors, Muscarinic; Receptors, Nicotinic; Tacrine; Torpedo; Xenopus	2005
Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge. Journal of medicinal chemistry, 2006, Sep-07, Volume: 49, Issue:18 Topics: Acetylcholinesterase; Alkenes; Animals; Binding Sites; Cholinesterase Inhibitors; Crystallization; Crystallography, X-Ray; Dimerization; Models, Molecular; Molecular Structure; Protein Conformation; Tacrine; Torpedo	2006
Stabilization of Torpedo californica acetylcholinesterase by reversible inhibitors. Biochemistry, 2009, Jan-27, Volume: 48, Issue:3 Topics: Acetylcholinesterase; Animals; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide; Calorimetry; Cholinesterase Inhibitors; Decamethonium Compounds; Disulfides; Elapid Venoms; Entropy; Enzyme Activation; Enzyme Stability; Guanidine; Humans; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Spin Labels; Tacrine; Temperature; Torpedo	2009
Affinity binding-guided fluorescent nanobiosensor for acetylcholinesterase inhibitors via distance modulation between the fluorophore and metallic nanoparticle. Analytical chemistry, 2012, Mar-20, Volume: 84, Issue:6 Topics: Acetylcholinesterase; Animals; Biosensing Techniques; Cholinesterase Inhibitors; Fish Proteins; Fluorescent Dyes; Limit of Detection; Metal Nanoparticles; Models, Molecular; Paraoxon; Protein Binding; Spectrometry, Fluorescence; Tacrine; Torpedo	2012
Structural basis of femtomolar inhibitors for acetylcholinesterase subtype selectivity: insights from computational simulations. Journal of molecular graphics & modelling, 2013, Volume: 41 Topics: Acetylcholinesterase; Acridines; Animals; Binding Sites; Cholinesterase Inhibitors; Drosophila melanogaster; Isoenzymes; Mice; Molecular Dynamics Simulation; Phenanthridines; Protein Binding; Structure-Activity Relationship; Tacrine; Thermodynamics; Torpedo; Triazoles	2013
Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography. Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1 Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Behavior, Animal; Benzofurans; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; Humans; Male; Mice; Mice, Inbred ICR; Models, Molecular; Nootropic Agents; Structure-Activity Relationship; Tacrine; Torpedo	2016
Effect on Acetylcholinesterase and Anti-oxidant Activity of Synthetic Chalcones having a Good Predicted Pharmacokinetic Profile. Medicinal chemistry (Shariqah (United Arab Emirates)), 2017, Volume: 13, Issue:7 Topics: Acetylcholinesterase; Animals; Antioxidants; Blood-Brain Barrier; Catalytic Domain; Chalcones; Cholinesterase Inhibitors; Cytochrome P-450 CYP3A; Gastrointestinal Absorption; Kinetics; Molecular Docking Simulation; Tacrine; Torpedo	2017
Design, synthesis, cholinesterase inhibition and molecular modelling study of novel tacrine hybrids with carbohydrate derivatives. Bioorganic & medicinal chemistry, 2018, 11-01, Volume: 26, Issue:20 Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Galactose; Humans; Mice; Molecular Docking Simulation; Ribose; Structure-Activity Relationship; Tacrine; Torpedo; Xylose	2018
Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer's compounds: In vitro and in vivo biological evaluation and docking study. Bioorganic chemistry, 2019, Volume: 83 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; Cholinesterase Inhibitors; Coumarins; Humans; Male; Maze Learning; Molecular Docking Simulation; Molecular Structure; Neuroprotective Agents; Nootropic Agents; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Tacrine; Torpedo; Triazoles	2019
Alignment-independent 3D-QSAR and molecular docking studies of tacrine-4-oxo-4H-Chromene hybrids as anti-Alzheimer's agents. Computational biology and chemistry, 2019, Volume: 80 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Benzopyrans; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Nootropic Agents; Protein Binding; Quantitative Structure-Activity Relationship; Tacrine; Torpedo	2019