tacrine and tacrine hydrochloride

tacrine has been researched along with tacrine hydrochloride in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carlier, PR; Chow, ES; El Yazal, J; Han, Y; Liu, J; Pang, YP1
Badia, A; Camps, P; Clos, MV; Formosa, X; Muñoz-Torrero, D; Petrignet, J1
Cieslik, JS; Elsinghorst, PW; Gütschow, M; Mohr, K; Tränkle, C1
Andrisano, V; Badia, A; Bartolini, M; Bidon-Chanal, A; Camins, A; Camps, P; Clos, MV; Estelrich, J; Formosa, X; Galdeano, C; Gómez, T; Lizondo, M; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Pallàs, M; Scarpellini, M; Viayna, E1
Feng, X; Hong, G; Li, G; Li, X; Liu, T; Mao, L; Xu, Z; Zhang, Y1
Abu-Serie, MM; AlFadly, ED; Bakkar, NZ; Bartolini, M; Belal, ASF; El-Yazbi, AF; Elkazaz, S; Elzahhar, PA; Ghareeb, DA; Iriepa, I; Janockova, J; Kobeissy, F; Moraleda, I; Rafeh, RW; Saudi, MNS; Shaltout, H; Soukup, O; Tramarin, A1

Other Studies

6 other study(ies) available for tacrine and tacrine hydrochloride

ArticleYear
Heterodimeric tacrine-based acetylcholinesterase inhibitors: investigating ligand-peripheral site interactions.
    Journal of medicinal chemistry, 1999, Oct-07, Volume: 42, Issue:20

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; In Vitro Techniques; Ligands; Protein Binding; Rats; Structure-Activity Relationship; Tacrine

1999
Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Acetylcholinesterase; Aminoquinolines; Animals; Binding Sites; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Structure-Activity Relationship; Tacrine

2005
First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor.
    Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23

    Topics: Acetylcholinesterase; Allosteric Regulation; Animals; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Gallamine Triethiodide; Humans; In Vitro Techniques; Ligands; Models, Molecular; Myocardium; Radioligand Assay; Receptor, Muscarinic M2; Structure-Activity Relationship; Swine; Tacrine

2007
Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Binding Sites; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Donepezil; Humans; Indans; Models, Molecular; Piperidines; Structure-Activity Relationship; Tacrine

2008
Synthesis and activity towards Alzheimer's disease in vitro: Tacrine, phenolic acid and ligustrazine hybrids.
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cholinesterase Inhibitors; Humans; Hydroxybenzoates; Models, Molecular; PC12 Cells; Pyrazines; Rats; Tacrine

2018
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Acetylcholine; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Inflammation; Lipoxygenase Inhibitors; Mice; Molecular Docking Simulation; Neurons; PC12 Cells; Rats; Semicarbazides; Triazoles

2019