tacrine has been researched along with quercetin in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 12 (80.00) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, X; Decker, M; Fleck, C; Heilmann, J; Kling, B; Kraus, B; Lupp, A; Zenger, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Ismaïli, L; Iutzeler, A; Luzet, V; Pudlo, M; Refouvelet, B; Tomassoli, I | 1 |
| Emami, S; Foroumadi, A; Ghanoni, F; Homayouni Moghadam, F; Khoobi, M; Moradi, A; Nadri, H; Pirali Hamedani, M; Shafiee, A; Vosooghi, M; Zadmard, R | 1 |
| Brazzolotto, X; Brus, B; Colletier, JP; Coquelle, N; Gobec, S; Knez, D; Mravljak, J; Šink, R; Sosič, I | 1 |
| Cen, J; Chen, Y; Hong, C; Luo, W; Wang, CJ; Wang, T; Xie, SQ; Yang, YC | 1 |
| Ameri, A; Emami, S; Forootanfar, H; Foroumadi, A; Haririan, I; Khoobi, M; Moghadam, FH; Mojtahedi, MM; Moradi, A; Nadri, H; Pourabdi, L; Shafiee, A | 1 |
| Asadipour, A; Bukhari, SNA; Emami, S; Firoozpour, L; Foroumadi, A; Golshani, M; Homayouni Moghadam, F; Jafari, M; Jalili-Baleh, L; Khoobi, M; Moradi, A; Nadri, H; Shakibaie, M | 1 |
| Andrisano, V; Apperley, KYP; Bartolini, M; Baschieri, A; Basso, M; Chen, HH; De Simone, A; Guardigni, M; Keillor, JW; Kobrlova, T; Milelli, A; Montanari, S; Soukup, O; Valgimigli, L | 1 |
| Han, J; Ji, L; Li, Z; Ma, J; Wang, M; Wu, M | 1 |
| Bartolini, M; Decker, M; Dolles, D; Falkeis, C; Gmeiner, P; Gunesch, S; Hoffmann, M; Hübner, H; Maitra, R; Marinelli, O; Maurice, T; Monti, B; Nabissi, M; Naldi, M; Petralla, S; Poeta, E; Scheiner, M; Vieth, M | 1 |
| Chen, S; Du, J; Li, R; Li, Z; Liu, T; Xing, S | 1 |
| İmamoğlu, R; Kısa, D; Koç, E | 1 |
15 other study(ies) available for tacrine and quercetin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Tacrine-silibinin codrug shows neuro- and hepatoprotective effects in vitro and pro-cognitive and hepatoprotective effects in vivo.
Topics: Acetylcholinesterase; Allosteric Regulation; Animals; Butyrylcholinesterase; Cell Count; Cell Line; Cell Survival; Cholinesterase Inhibitors; Cognition; Eels; Female; Glutamic Acid; Hepatic Stellate Cells; Horses; Lipid Peroxidation; Liver; Maze Learning; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Silybin; Silymarin; Tacrine | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Quinolone-benzylpiperidine derivatives as novel acetylcholinesterase inhibitor and antioxidant hybrids for Alzheimer disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Antioxidants; Binding Sites; Catalytic Domain; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Piperidines; Quinolones; Structure-Activity Relationship | 2014 |
New tetracyclic tacrine analogs containing pyrano[2,3-c]pyrazole: efficient synthesis, biological assessment and docking simulation study.
Topics: Animals; Butyrylcholinesterase; Cell Death; Cholinesterase Inhibitors; Drug Design; Electrophorus; Heterocyclic Compounds, 4 or More Rings; Horses; Hydrogen Peroxide; Kinetics; Molecular Docking Simulation; Neuroprotective Agents; PC12 Cells; Pyrans; Pyrazoles; Rats; Tacrine | 2015 |
Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Binding Sites; Butyrylcholinesterase; Chelating Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; Humans; Metals; Molecular Docking Simulation; Nitroquinolines; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Spectrophotometry, Ultraviolet | 2015 |
Design, synthesis and evaluation of 4-dimethylamine flavonoid derivatives as potential multifunctional anti-Alzheimer agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Death; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Dimethylamines; Drug Design; Flavonoids; Humans; Hydrogen Peroxide; Intracellular Space; Kinetics; Molecular Docking Simulation; PC12 Cells; Peptide Fragments; Protein Aggregates; Protein Conformation; Rats; Structure-Activity Relationship | 2016 |
Synthesis and structure-activity relationship study of tacrine-based pyrano[2,3-c]pyrazoles targeting AChE/BuChE and 15-LOX.
Topics: Acetylcholinesterase; Arachidonate 15-Lipoxygenase; Blood-Brain Barrier; Butyrylcholinesterase; Cell Survival; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Hep G2 Cells; Humans; Lipoxygenase Inhibitors; Molecular Docking Simulation; Protein Conformation; Pyrazoles; Structure-Activity Relationship; Tacrine | 2016 |
New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Death; Cell Proliferation; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Hydrogen Peroxide; Molecular Structure; Neuroprotective Agents; PC12 Cells; Phthalazines; Protein Aggregates; Pyrazoles; Rats; Structure-Activity Relationship | 2017 |
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cinnamates; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycogen Synthase Kinase 3 beta; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2017 |
Design, synthesis, and biological evaluation of rutacecarpine derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Line, Tumor; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protective Agents; Protein Multimerization; Rats; Structure-Activity Relationship; Sulfonamides | 2019 |
Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo.
Topics: Animals; Cholinesterases; Humans; Ligands; Mice; Neuroprotective Agents; Receptor, Cannabinoid, CB2 | 2019 |
Design, synthesis, and biological evaluation of novel (4-(1,2,4-oxadiazol-5-yl)phenyl)-2-aminoacetamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetamides; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Biphenyl Compounds; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Neuroprotective Agents; Oxadiazoles; Picrates; Protein Aggregates; Structure-Activity Relationship | 2022 |
Polyphenolic compounds: Synthesis, assessment of antimicrobial effect and enzymes inhibition against important medicinal enzymes with computational details.
Topics: Acetylcholinesterase; Anti-Infective Agents; Antioxidants; Cholinesterase Inhibitors; Cholinesterases; Humans; Molecular Docking Simulation; Molecular Structure; Monophenol Monooxygenase; Structure-Activity Relationship | 2022 |