tacrine and profenamine

tacrine has been researched along with profenamine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campiani, G; Catalanotti, B; Chiasserini, L; Fattorusso, C; Gaeta, A; McKissic, D; Novellino, E; Pellerano, C; Savini, L; Saxena, A1
Agnusdei, M; Belinskaya, T; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fedorko, JM; Gaeta, A; Gemma, S; Greig, NH; Holloway, HW; Nacci, V; Novellino, E; Persico, M; Savini, L; Saxena, A1
Boido, V; Carotti, A; Catto, M; Giangreco, I; Nicolotti, O; Novelli, F; Pisani, L; Sparatore, A; Sparatore, F; Tasso, B; Tonelli, M1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brus, B; Colletier, JP; Coquelle, N; Gobec, S; Kos, J; Košak, U; Pišlar, A; Stojan, J; Turk, S1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW1
Williams, A; Zhan, CG; Zhou, S1

Other Studies

7 other study(ies) available for tacrine and profenamine

ArticleYear
Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors.
    Journal of medicinal chemistry, 2003, Jan-02, Volume: 46, Issue:1

    Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Ligands; Models, Molecular; Structure-Activity Relationship; Tacrine

2003
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Acetylcholinesterase; Acridines; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; In Vitro Techniques; Ligands; Models, Molecular; Molecular Probes; Structure-Activity Relationship

2005
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Crystallography, X-Ray; Dose-Response Relationship, Drug; Erythrocytes; Models, Molecular; Molecular Structure; Quinolizidines; Stereoisomerism; Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.
    Journal of medicinal chemistry, 2014, Oct-09, Volume: 57, Issue:19

    Topics: Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Crystallization; Drug Discovery; Humans; Mice; Molecular Docking Simulation; Peptide Fragments; Protein Aggregates; Stereoisomerism

2014
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries

2017
Discovery of potent and selective butyrylcholinesterase inhibitors through the use of pharmacophore-based screening.
    Bioorganic & medicinal chemistry letters, 2019, 12-15, Volume: 29, Issue:24

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Humans; Molecular Structure; Structure-Activity Relationship

2019