tacrine has been researched along with n-methylaspartate in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hershkowitz, N; Rogawski, MA | 1 |
| Choi, DW; Davenport, CJ; Monyer, H | 1 |
| Albuquerque, EX; Costa, AC | 1 |
| Chuang, DM; Ishitani, R; Sunaga, K | 1 |
| Beyreuther, K; Emilien, G; Maloteaux, JM; Masters, CL | 1 |
| Chang, DC; Chen, C; Fu, H; Han, Y; Lao, Y; Lee, NT; Li, M; Li, P; Li, W; Liu, W; Liu, Y; Pang, Y; Tsim, KW; Yu, H | 1 |
| Fu, H; Han, Y; Huang, P; Lee, NT; Li, C; Li, W; Li, ZW; Liu, Y; Luo, J; Pang, Y; Xia, J; Yu, H; Zhang, W | 1 |
| Ai, YX; Han, YF; Li, CY; Li, ZW; Liu, LJ; Liu, YW; Luo, JL; Pang, YP; Peoples, RW; Ren, H | 1 |
| Fujiwara, H; Inada, C; Matsumoto, K; Miyata, T; Thi Le, X; Tsuneyama, K | 1 |
| Li, C; Liu, Y | 1 |
1 review(s) available for tacrine and n-methylaspartate
| Article | Year |
|---|---|
Prospects for pharmacological intervention in Alzheimer disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspartic Acid Endopeptidases; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Endopeptidases; Hippocampus; Humans; Indans; N-Methylaspartate; Nerve Growth Factors; Nicotine; Piperidines; Tacrine | 2000 |
9 other study(ies) available for tacrine and n-methylaspartate
| Article | Year |
|---|---|
Tetrahydroaminoacridine block of N-methyl-D-aspartate-activated cation channels in cultured hippocampal neurons.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Ion Channel Gating; Ion Channels; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substrate Specificity; Tacrine | 1991 |
Tetrahydroaminoacridine selectively attenuates NMDA receptor-mediated neurotoxicity.
Topics: Aminoacridines; Animals; Aspartic Acid; Cells, Cultured; Cholinesterase Inhibitors; Glutamates; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tacrine | 1988 |
Dynamics of the actions of tetrahydro-9-aminoacridine and 9-aminoacridine on glutamatergic currents: concentration-jump studies in cultured rat hippocampal neurons.
Topics: Aminacrine; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Rats; Receptors, Glutamate; Tacrine | 1994 |
Tetrahydroaminoacridine is neurotrophic and promotes the expression of muscarinic receptor-coupled phosphoinositide turnover in differentiating cerebellar granule cells.
Topics: 4-Aminopyridine; Animals; Carbachol; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Kinetics; N-Methylaspartate; Neurons; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tacrine | 1993 |
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons.
Topics: Animals; Apoptosis; Blotting, Western; Cells, Cultured; Cerebellum; Energy Metabolism; Glutamic Acid; Mitochondria; Mitochondrial Proteins; N-Methylaspartate; Neurons; Oxidative Stress; Proteome; Proteomics; Rats; Tacrine | 2007 |
Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents.
Topics: Allosteric Site; Animals; Cells, Cultured; Dimerization; Hydrogen-Ion Concentration; Ion Channel Gating; N-Methylaspartate; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Tacrine | 2007 |
Inhibition of NMDA-gated ion channels by bis(7)-tacrine: whole-cell and single-channel studies.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Ion Channel Gating; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tacrine; Transfection | 2008 |
Endogenous acetylcholine rescues NMDA-induced long-lasting hippocampal cell damage via stimulation of muscarinic M(1) receptors: elucidation using organic hippocampal slice cultures.
Topics: Acetylcholine; Animals; Blotting, Western; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Galantamine; Hippocampus; Indans; Mice; Mice, Inbred ICR; N-Methylaspartate; Organ Culture Techniques; Piperidines; Receptor, Muscarinic M1; Tacrine | 2013 |
Inhibition of N-methyl-D-aspartate-activated current by bis(7)-tacrine in HEK-293 cells expressing NR1/NR2A or NR1/NR2B receptors.
Topics: Cell Line; HEK293 Cells; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Tacrine | 2012 |