tacrine and ith 4012

tacrine has been researched along with ith 4012 in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barril, X; de los Ríos, C; García, AG; Huertas, O; León, R; López, MG; Luque, FJ; Marco-Contelles, J; Villarroya, M	1
de Los Ríos, C; Egea, J; Gálvez, E; García, AG; Iriepa, I; León, R; López, MG; Marco-Contelles, J; Moraleda, I; Romero, A; Samadi, A; Villarroya, M	1
de Los Ríos, C; Marco-Contelles, J	1

Reviews

1 review(s) available for tacrine and ith 4012

Article	Year
Tacrines for Alzheimer's disease therapy. III. The PyridoTacrines. European journal of medicinal chemistry, 2019, Mar-15, Volume: 166 Topics: Alzheimer Disease; Animals; Drug Discovery; Humans; Tacrine	2019

Other Studies

2 other study(ies) available for tacrine and ith 4012

Article	Year
New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties. Bioorganic & medicinal chemistry, 2008, Aug-15, Volume: 16, Issue:16 Topics: Acetylcholinesterase; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dihydropyridines; Humans; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Neuroprotective Agents; Reactive Oxygen Species; Spectrophotometry, Infrared; Tacrine	2008
Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives. Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Calcium; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytotoxins; Electron Transport Chain Complex Proteins; Electrophorus; Glucose; Hippocampus; Humans; Isomerism; Models, Molecular; Naphthyridines; Neuroprotective Agents; Okadaic Acid; Oligomycins; Oxygen; Peptide Fragments; Protein Binding; Protein Phosphatase 2; Rats; Rotenone; Structure-Activity Relationship	2010

Article

Year

New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties.

Bioorganic & medicinal chemistry, 2008, Aug-15, Volume: 16, Issue:16

Topics: Acetylcholinesterase; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dihydropyridines; Humans; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Neuroprotective Agents; Reactive Oxygen Species; Spectrophotometry, Infrared; Tacrine

2008

Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.

Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Calcium; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytotoxins; Electron Transport Chain Complex Proteins; Electrophorus; Glucose; Hippocampus; Humans; Isomerism; Models, Molecular; Naphthyridines; Neuroprotective Agents; Okadaic Acid; Oligomycins; Oxygen; Peptide Fragments; Protein Binding; Protein Phosphatase 2; Rats; Rotenone; Structure-Activity Relationship

2010