Compounds > tacrine

tacrine and dihydropyridines

tacrine has been researched along with dihydropyridines in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barzaghi, F; M'Harzi, M; Oberlander, C; Palou, AM1
Cutler, NR; Sramek, JJ1
Palacios, JM1
Bymaster, FP; Calligaro, DO; Carter, PA; DeLapp, N; Fink-Jensen, A; Jeppesen, L; Mitch, CH; Peters, SC; Rimvall, K; Sauerberg, P; Shannon, HE; Sheardown, MJ; Ward, JS; Whitesitt, CA; Zhang, W1
Callahan, MJ1
de Los Ríos, C; García, AG; Guglietta, A; León, R; López, MG; Marco-Contelles, J; Terencio, J; Villarroya, M1
Barril, X; de los Ríos, C; García, AG; Huertas, O; León, R; López, MG; Luque, FJ; Marco-Contelles, J; Villarroya, M1
Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M1

Other Studies

8 other study(ies) available for tacrine and dihydropyridines

ArticleYear
Antagonism of scopolamine-induced memory impairments in rats by the muscarinic agonist RU 35,926 (CI-979).
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:1

    Topics: Animals; Dihydropyridines; Male; Maze Learning; Memory; Memory, Short-Term; Muscarinic Agonists; Oximes; Psychotropic Drugs; Rats; Rats, Wistar; Scopolamine; Synaptic Transmission; Tacrine

1995
Scientific and ethical concerns in clinical trials in Alzheimer's patients: the bridging study.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:6

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dihydropyridines; Ethics, Medical; Humans; Nootropic Agents; Oximes; Physostigmine; Psychotropic Drugs; Pyridines; Tacrine; Thiadiazoles

1995
Alzheimer's disease: new pharmacological perspectives.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18 Suppl B

    Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Dihydropyridines; Donepezil; Humans; Indans; Muscarinic Agonists; Oximes; Phenylcarbamates; Piperidines; Pyridines; Rivastigmine; Tacrine; Thiadiazoles

1996
Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects.
    Brain research, 1998, Jun-08, Volume: 795, Issue:1-2

    Topics: Animals; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Agents; Cholinesterase Inhibitors; Dihydropyridines; Dose-Response Relationship, Drug; Hydrolysis; Hypothermia; Imines; Lithium; Male; Mice; Mice, Inbred Strains; Muscarinic Agonists; Oximes; Parasympathomimetics; Phosphatidylinositols; Physostigmine; Pilocarpine; Pyridines; Quinuclidines; Radioligand Assay; Salivation; Tacrine; Tetrazoles; Thiadiazoles; Tremor

1998
Combining tacrine with milameline reverses a scopolamine-induced impairment of continuous performance in rhesus monkeys.
    Psychopharmacology, 1999, Volume: 144, Issue:3

    Topics: Animals; Cholinesterase Inhibitors; Dihydropyridines; Drug Interactions; Female; Macaca mulatta; Male; Muscarinic Agonists; Oximes; Psychomotor Performance; Scopolamine; Tacrine

1999
Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Calcium; Calcium Channels; Cell Proliferation; Cells, Cultured; Dihydropyridines; Eels; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Neuroblastoma; Neuroprotective Agents; Structure-Activity Relationship; Tacrine

2006
New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties.
    Bioorganic & medicinal chemistry, 2008, Aug-15, Volume: 16, Issue:16

    Topics: Acetylcholinesterase; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dihydropyridines; Humans; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Neuroprotective Agents; Reactive Oxygen Species; Spectrophotometry, Infrared; Tacrine

2008
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine

2009