tacrine has been researched along with decamethonium in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrisano, V; Bartolini, M; Bidon-Chanal, A; de Austria, C; del Monte-Millán, M; Dorronsoro, I; García-Palomero, E; Luque, FJ; Martínez, A; Medina, M; Muñoz-Ruiz, P; Orozco, M; Rubio, L; Usán, P; Valenzuela, R | 1 |
| Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A | 1 |
| Al-Rashid, ZF; Beri, V; Cheung, J; Rosenberry, TL; Shiomi, K; Wildman, SA | 1 |
| Axelsen, P; Harel, M; Raves, M; Silman, I; Sussman, JL | 1 |
| Axelsen, PH; Bouet, F; Ehret-Sabatier, L; Goeldner, M; Harel, M; Hirth, C; Schalk, I; Silman, I; Sussman, JL | 1 |
| Ashani, Y; Konstantinovskii, L; Roth, E; Shnyrov, VL; Silman, I; Weiner, L | 1 |
1 review(s) available for tacrine and decamethonium
| Article | Year |
|---|---|
Three-dimensional structures of acetylcholinesterase and of its complexes with anticholinesterase agents.
Topics: Acetylcholinesterase; Animals; Binding Sites; Cholinesterase Inhibitors; Decamethonium Compounds; Edrophonium; Electrochemistry; In Vitro Techniques; Macromolecular Substances; Models, Molecular; Molecular Structure; Protein Conformation; Tacrine | 1994 |
5 other study(ies) available for tacrine and decamethonium
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Binding Sites; Butyrylcholinesterase; Cattle; Cell Line, Tumor; Cholinesterase Inhibitors; Dimerization; Drug Design; Erythrocytes; Fluorometry; Humans; Models, Molecular; Nootropic Agents; Protein Binding; Structure-Activity Relationship; Tacrine | 2005 |
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine | 2008 |
The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.
Topics: Acetylcholine; Acetylcholinesterase; Aflatoxin B1; Binding Sites; Binding, Competitive; Catalysis; Catalytic Domain; Cholinesterase Inhibitors; Crystallography, X-Ray; Furans; Humans; Hydrolysis; Kinetics; Models, Chemical; Phenanthrenes; Pyrans; Quinones; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2013 |
Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.
Topics: Acetylcholine; Acetylcholinesterase; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Decamethonium Compounds; Edrophonium; Hydrogen Bonding; Ligands; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Quaternary Ammonium Compounds; Tacrine; Torpedo | 1993 |
Stabilization of Torpedo californica acetylcholinesterase by reversible inhibitors.
Topics: Acetylcholinesterase; Animals; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide; Calorimetry; Cholinesterase Inhibitors; Decamethonium Compounds; Disulfides; Elapid Venoms; Entropy; Enzyme Activation; Enzyme Stability; Guanidine; Humans; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Spin Labels; Tacrine; Temperature; Torpedo | 2009 |