tacrine and cysteine

tacrine has been researched along with cysteine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hallikainen, M; Helkala, EL; Kuikka, J; Riekkinen, P; Soininen, H1
Helkala, EL; Kuikka, J; Laakso, M; Partanen, J; Riekkinen, M; Riekkinen, P; Soininen, H1
Cusack, B; Fauq, A; Hughes, TF; Johnson, JL; McCullough, EH; Romanovskis, P; Rosenberry, TL; Spatola, AF1
Boyd, AE; Dunlop, CS; Johnson, DA; Radic, Z; Taylor, P; Wong, L1
Akaike, A; Fujii, T; Katsuki, H; Kume, T; Niidome, T; Okabe, S; Sugimoto, H; Sugimoto, M; Takada-Takatori, Y1
Jing, L; Liang, C; Shi, X; Tian, Y; Xian, Y; Ye, S1
Chaves, S; Keri, RS; Quintanova, C; Santos, MA1
Cardoso, SM; Chaves, S; Keri, RS; Quintanova, C; Santos, MA; Silva, DF1

Trials

2 trial(s) available for tacrine and cysteine

ArticleYear
Tetrahydroaminoacridine modulates technetium-99m labelled ethylene dicysteinate retention in Alzheimer's disease measured with single photon emission computed tomography imaging.
    Neuroscience letters, 1995, Jul-28, Volume: 195, Issue:1

    Topics: Aged; Alzheimer Disease; Brain; Cerebellum; Cholinesterase Inhibitors; Cysteine; Double-Blind Method; Female; Humans; Male; Nootropic Agents; Organotechnetium Compounds; Tacrine; Tomography, Emission-Computed, Single-Photon

1995
Tetrahydroaminoacridine improves the recency effect in Alzheimer's disease.
    Neuroscience, 1998, Volume: 83, Issue:2

    Topics: Aged; Alzheimer Disease; Amygdala; Apolipoprotein E4; Apolipoproteins E; Cerebrovascular Circulation; Cholinesterase Inhibitors; Cysteine; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Memory, Short-Term; Parasympathetic Nervous System; Plaque, Amyloid; Tacrine; Tomography, Emission-Computed, Single-Photon

1998

Other Studies

6 other study(ies) available for tacrine and cysteine

ArticleYear
Inhibitors tethered near the acetylcholinesterase active site serve as molecular rulers of the peripheral and acylation sites.
    The Journal of biological chemistry, 2003, Oct-03, Volume: 278, Issue:40

    Topics: Acetylcholinesterase; Binding Sites; Cations; Cysteine; Disulfides; Dose-Response Relationship, Drug; Humans; Hydrolysis; Kinetics; Ligands; Models, Chemical; Models, Molecular; Models, Statistical; Mutagenesis, Site-Directed; Mutation; Propidium; Protein Binding; Recombinant Proteins; Tacrine

2003
Nanosecond dynamics of acetylcholinesterase near the active center gorge.
    The Journal of biological chemistry, 2004, Jun-18, Volume: 279, Issue:25

    Topics: Acetylcholinesterase; Anisotropy; Binding Sites; Catalysis; Cell Line; Cysteine; DNA Mutational Analysis; Elapid Venoms; Humans; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Tacrine; Time Factors

2004
Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity.
    European journal of pharmacology, 2006, Nov-07, Volume: 549, Issue:1-3

    Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Cysteine; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Fetus; Galantamine; Glutamic Acid; Ionomycin; Ionophores; Mecamylamine; Neuroprotective Agents; Nicotinic Antagonists; Nitric Oxide Donors; Rats; Rats, Wistar; S-Nitrosothiols; Tacrine

2006
An electrochemical platform for acetylcholinesterase activity assay and inhibitors screening based on Michael addition reaction between thiocholine and catechol-terminated SAMs.
    The Analyst, 2011, Dec-07, Volume: 136, Issue:23

    Topics: Acetylcholinesterase; Acetylthiocholine; Biosensing Techniques; Carbofuran; Catechols; Cholinesterase Inhibitors; Cysteine; Electrochemical Techniques; Electrodes; Glutathione; Gold; Methyl Parathion; Tacrine; Thiocholine

2011
Copper(II) complexation of tacrine hybrids with potential anti-neurodegenerative roles.
    Journal of inorganic biochemistry, 2015, Volume: 151

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Chelating Agents; Cholinesterase Inhibitors; Coordination Complexes; Copper; Cysteine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Tacrine

2015
New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease.
    Chemical biology & drug design, 2016, Volume: 87, Issue:1

    Topics: Acetylcholinesterase; Alzheimer Disease; Blood-Brain Barrier; Cell Line, Tumor; Cholinesterase Inhibitors; Cysteine; Humans; Tacrine

2016