tacrine has been researched along with choline in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (23.33) | 18.7374 |
| 1990's | 13 (43.33) | 18.2507 |
| 2000's | 8 (26.67) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karplus, M; So, SS | 1 |
| Dolezal, V; Tucek, S | 3 |
| Karlén, B; Kimland, M; Nordgren, I | 1 |
| Miyoshi, K; Ueki, A | 1 |
| Buyukuysal, RL; Wurtman, RJ | 1 |
| Cohen, S; Gitter, S; Reicher, S; Speiser, Z | 1 |
| Miyoshi, I; Taira, H; Ueki, A | 1 |
| Giacobini, E; Hallak, M | 1 |
| Russell, RW | 1 |
| Kameyama, T; Nabeshima, T; Yoshida, S | 1 |
| Branconnier, RJ; Miller, LL | 1 |
| Abe, E; Itoh, T; Masuda, Y; Murai, S; Odashima, J; Saito, H | 1 |
| Nordberg, A | 1 |
| Clarke, PB; el-Bizri, H; Reuben, M | 1 |
| Bessho, T; Chaki, H; Egawa, M; Ohshima, C; Saito, K; Tabata, R; Takashina, K; Tobe, A; Yamabe, H | 1 |
| Goto, G; Hayako, H; Hirai, K; Ishihara, Y; Kato, K; Miyamoto, M; Nakayama, T | 1 |
| Bachurin, S; Lermontova, N; Lukoyanov, N; Lukoyanova, E; Serkova, T | 1 |
| Cheng, DH; Tang, XC | 1 |
| Carlier, PR; Han, Y; Ho, W; Lee, NT; Liu, J; Pang, Y | 1 |
| Bachurin, SO; Lermontova, NN; Lukoyanov, NV; Lukoyanova, EA; Serkova, TP | 1 |
| Carelli, V; Di Stefano, A; Giorgioni, G; Liberatore, F; Marra, R; Rispoli, V; Rotiroti, D; Scipione, L | 1 |
| Cohen, SA; Finch, JW; Wall, DB | 1 |
| Kang, YS; Lee, KE; Lee, NY; Terasaki, T | 1 |
| Carelli, V; Costa, N; De Vita, D; Liberatore, F; Marra, R; Rispoli, V; Rotiroti, D; Scipione, L | 1 |
| Bessho, T; Eguchi, J; Mori, R; Saito, K; Takashina, K | 1 |
| Cheng, K; Davis, RJ; Drachenberg, C; Nomikos, G; Raufman, JP; Samimi, R; Shant, J; Wade, M; Xie, G | 1 |
| Alves, G; Falcao, A; Matias, M; Silvestre, S | 1 |
| Korabecny, J; Kristofikova, Z; Kuca, K; Nepovimova, E; Ricny, J; Ripova, D; Soukup, O | 1 |
4 review(s) available for tacrine and choline
| Article | Year |
|---|---|
Behavioral correlates of presynaptic events in the cholinergic neurotransmitter system.
Topics: Acetylcholine; Aging; Behavior; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Cholinesterases; Humans; Nerve Growth Factors; Neurotransmitter Agents; Tacrine | 1988 |
Cannabis: effects on memory and the cholinergic limbic system.
Topics: Acetylcholine; Acetylcholinesterase; Cannabinoids; Cannabis; Choline; Dronabinol; Habituation, Psychophysiologic; Hippocampus; Humans; Limbic System; Memory; Mental Recall; Models, Biological; Parasympatholytics; Physostigmine; Tacrine; Transfer, Psychology | 1983 |
In vivo detection of neurotransmitter changes in Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Brain; Choline; Humans; Neurotransmitter Agents; Receptors, Muscarinic; Receptors, Nicotinic; Tacrine | 1993 |
Recent Highlights on Molecular Hybrids Potentially Useful in Central Nervous System Disorders.
Topics: Analgesics; Central Nervous System Diseases; Choline; Donepezil; Epilepsy; gamma-Aminobutyric Acid; Humans; Indans; Opioid Peptides; Pain; Piperidines; Tacrine | 2017 |
26 other study(ies) available for tacrine and choline
| Article | Year |
|---|---|
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
Topics: Cholinesterase Inhibitors; Dopamine beta-Hydroxylase; Drug Design; Enzyme Inhibitors; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Conformation; Molecular Structure; Neural Networks, Computer; Phosphorylases; Receptors, Aryl Hydrocarbon; Static Electricity; Structure-Activity Relationship | 1997 |
Investigation of the mechanism of the effect of tacrine (tetrahydroaminoacridine) on the metabolism of acetylcholine and choline in brain cortical prisms.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Cerebral Cortex; Choline; Hemicholinium 3; In Vitro Techniques; Male; Nerve Endings; Paraoxon; Phosphatidylcholines; Phosphorylation; Phosphorylcholine; Rats; Rats, Wistar; Tacrine | 1992 |
Metrifonate and tacrine: a comparative study on their effect on acetylcholine dynamics in mouse brain.
Topics: Acetylcholine; Animals; Brain; Choline; Male; Mice; Tacrine; Trichlorfon | 1992 |
Negative effects of tacrine (tetrahydroaminoacridine) and methoxytacrine on the metabolism of acetylcholine in brain slices incubated under conditions stimulating neurotransmitter release.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Brain; Choline; Choline O-Acetyltransferase; Histological Techniques; In Vitro Techniques; Neurotransmitter Agents; Potassium; Rats; Tacrine | 1991 |
Reversal of learning impairment in ventral globus pallidus-lesioned rats by combination of continuous intracerebroventricular choline infusion and oral cholinergic drug administration.
Topics: Acetylcholine; Administration, Oral; Aminoquinolines; Animals; Avoidance Learning; Brain Chemistry; Cerebral Cortex; Choline; Cholinesterase Inhibitors; Electroshock; Globus Pallidus; Injections, Intraventricular; Learning Disabilities; Male; Memory; Motor Activity; Parasympathomimetics; Psychotropic Drugs; Rats; Rats, Inbred Strains; Tacrine | 1991 |
Positive and negative effects of tacrine (tetrahydroaminoacridine) and methoxytacrine on the metabolism of acetylcholine in brain cortical prisms incubated under "resting" conditions.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Cerebral Cortex; Choline; Cholinesterases; Hemicholinium 3; Histological Techniques; Male; Rats; Rest; Tacrine | 1991 |
Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes.
Topics: 4-Aminopyridine; Aminoacridines; Aminopyridines; Animals; Choline; Choline O-Acetyltransferase; Corpus Striatum; Hippocampus; Male; Rats; Rats, Inbred Strains; Synaptosomes; Tacrine | 1989 |
Tacrine or arecoline mediates reversal of anoxia- or AF64A-induced behavioural disorders in the developing rat.
Topics: Animals; Animals, Suckling; Arecoline; Avoidance Learning; Aziridines; Behavior, Animal; Choline; Female; Hypoxia; Male; Motor Activity; Neuromuscular Blocking Agents; Parasympathomimetics; Pupil; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tacrine | 1989 |
[Study on Alzheimer's disease and the animal disease model--special reference to acetylcholinergic system].
Topics: Acetylcholine; Alzheimer Disease; Animals; Cerebral Cortex; Choline; Choline O-Acetyltransferase; Disease Models, Animal; Drug Therapy, Combination; Learning; Male; Rats; Rats, Inbred Strains; Tacrine | 1989 |
Physostigmine, tacrine and metrifonate: the effect of multiple doses on acetylcholine metabolism in rat brain.
Topics: Acetylcholine; Aminoacridines; Animals; Brain; Brain Chemistry; Caudate Nucleus; Choline; Choline O-Acetyltransferase; Cholinesterases; Male; Physostigmine; Rats; Rats, Inbred Strains; Tacrine; Time Factors; Trichlorfon | 1989 |
Effects of the novel compound NIK-247 on impairment of passive avoidance response in mice.
Topics: Aminoquinolines; Amnesia; Animals; Avoidance Learning; Choline; Cholinesterase Inhibitors; Cycloheximide; Electroshock; gamma-Aminobutyric Acid; Male; Memory; Mice; Phencyclidine; Picrotoxin; Tacrine | 1988 |
MKC-231, a choline uptake enhancer, ameliorates working memory deficits and decreased hippocampal acetylcholine induced by ethylcholine aziridinium ion in mice.
Topics: Acetylcholine; Acetylcholinesterase; Amnesia; Animals; Aziridines; Choline; Choline Deficiency; Data Interpretation, Statistical; Habituation, Psychophysiologic; Hippocampus; Indoles; Injections, Intraventricular; Male; Maze Learning; Memory; Memory Disorders; Mice; Mice, Inbred Strains; Pyridines; Quinolines; Synaptic Transmission; Tacrine | 1994 |
Blockade of nicotinic responses by physostigmine, tacrine and other cholinesterase inhibitors in rat striatum.
Topics: Animals; Choline; Cholinesterase Inhibitors; Corpus Striatum; Dopamine; Drug Interactions; In Vitro Techniques; Male; Nicotine; Nicotinic Antagonists; Physostigmine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission; Synaptosomes; Tacrine; Tritium | 1994 |
Effect of the novel high affinity choline uptake enhancer 2-(2-oxopyrrolidin-1-yl)-N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b] quinolin-4-yl)acetoamide on deficits of water maze learning in rats.
Topics: Acetylcholinesterase; Animals; Aziridines; Body Temperature; Choline; Hippocampus; In Vitro Techniques; Male; Maze Learning; Neuromuscular Blocking Agents; Nootropic Agents; Quinolines; Rats; Rats, Wistar; Receptors, Muscarinic; Salivation; Tacrine; Tremor | 1996 |
Neurochemical effects of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-b enzazepin-8-yl)-1-propanone fumarate (TAK-147), a novel acetylcholinesterase inhibitor, in rats.
Topics: Acetylcholinesterase; Animals; Benzazepines; Biogenic Monoamines; Butyrylcholinesterase; Choline; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Learning; Male; Memory; Norepinephrine; Rats; Rats, Wistar; Receptors, Cholinergic; Serotonin; Tacrine | 1997 |
Effects of tacrine on deficits in active avoidance performance induced by AF64A in rats.
Topics: Animals; Avoidance Learning; Aziridines; Choline; Hippocampus; Injections, Intravenous; Male; Neuromuscular Blocking Agents; Nootropic Agents; Rats; Rats, Wistar; Tacrine | 1998 |
Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities.
Topics: Alkaloids; Animals; Aziridines; Choline; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Dose-Response Relationship, Drug; Female; Indans; Injections, Intraventricular; Male; Maze Learning; Memory; Memory, Short-Term; Neuromuscular Blocking Agents; Piperidines; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tacrine | 1998 |
Bis(7)-tacrine, a novel acetylcholinesterase inhibitor, reverses AF64A-induced deficits in navigational memory in rats.
Topics: Animals; Aziridines; Choline; Cholinesterase Inhibitors; Escape Reaction; Injections, Intraventricular; Male; Maze Learning; Memory; Rats; Rats, Sprague-Dawley; Reaction Time; Tacrine; Toxins, Biological | 2000 |
Dimebon improves learning in animals with experimental Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Aziridines; Choline; Cholinesterase Inhibitors; Disease Models, Animal; Histamine H1 Antagonists; Indoles; Injections, Intraventricular; Male; Neuromuscular Blocking Agents; Rats; Rats, Wistar; Tacrine | 2000 |
Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Basal Nucleus of Meynert; Cell Count; Choline; Cholinesterase Inhibitors; Cognition Disorders; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Esters; Immunohistochemistry; Male; Maze Learning; Memory Disorders; Propiophenones; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Scopolamine; Spatial Behavior; Tacrine; Time Factors | 2004 |
Comparison of desorption/ionization on silicon (DIOS) time-of-flight and liquid chromatography/tandem mass spectrometry for assaying enzyme-inhibition reactions.
Topics: Acetylcholine; Acetylcholinesterase; Choline; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Kinetics; Mass Spectrometry; Silicon; Tacrine | 2004 |
Donepezil, tacrine and alpha-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB).
Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Cell Line, Transformed; Central Nervous System Agents; Choline; Cyclic N-Oxides; Donepezil; Endothelial Cells; Indans; Models, Biological; Nerve Tissue Proteins; Nitrogen Oxides; Organic Cation Transport Proteins; Piperidines; Plasma Membrane Neurotransmitter Transport Proteins; Rats; Symporters; Tacrine | 2005 |
Choline pivaloyl ester strengthened the benefit effects of Tacrine and Galantamine on electroencephalographic and cognitive performances in nucleus basalis magnocellularis-lesioned and aged rats.
Topics: Animals; Behavior, Animal; Choline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Enzyme Inhibitors; Galantamine; Male; Rats; Rats, Wistar; Scopolamine; Tacrine | 2006 |
MKC-231, a choline uptake enhancer: (2) Effect on synthesis and release of acetylcholine in AF64A-treated rats.
Topics: Acetylcholine; Analysis of Variance; Animals; Aziridines; Choline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; In Vitro Techniques; Male; Microdialysis; Neuromuscular Blocking Agents; Potassium; Quinolines; Rats; Rats, Wistar; Synaptosomes; Tacrine; Tritium | 2008 |
Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation.
Topics: Acetylcholine; Acetylcholinesterase; Atropine; Autocrine Communication; Caco-2 Cells; Cell Proliferation; Choline; Choline O-Acetyltransferase; Cholinergic Agents; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dose-Response Relationship, Drug; Electrochemistry; Hemicholinium 3; HT29 Cells; Humans; Immunohistochemistry; Membrane Transport Proteins; Muscarinic Antagonists; Physostigmine; Piperidines; Polymerase Chain Reaction; Receptor, Muscarinic M3; RNA, Messenger; Tacrine | 2008 |
Inhibitors of Acetylcholinesterase Derived from 7-Methoxytacrine and Their Effects on the Choline Transporter CHT1.
Topics: Alkylation; Amyloid beta-Peptides; Animals; Cation Transport Proteins; Cerebral Cortex; Cholesterol; Choline; Cholinesterase Inhibitors; Hippocampus; Male; Membrane Fluidity; Membrane Microdomains; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Stereoisomerism; Synaptosomes; Tacrine | 2017 |