tacrine and caffeic acid

tacrine has been researched along with caffeic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Chao, X; Cheng, Z; He, X; Huang, Y; Jin, M; Liu, P; Liu, S; Pi, R; Qin, J; Rapposelli, S; Tan, Y; Wang, Y; Yang, Y; Yu, J; Zhou, X1
Chen, Z; Chu, J; Digiacomo, M; Han, Y; Lapucci, A; Macchia, M; Pi, R; Rapposelli, S; Wang, S; Yang, X1
Andrisano, V; Apperley, KYP; Bartolini, M; Baschieri, A; Basso, M; Chen, HH; De Simone, A; Guardigni, M; Keillor, JW; Kobrlova, T; Milelli, A; Montanari, S; Soukup, O; Valgimigli, L1
İmamoğlu, R; Kısa, D; Koç, E1
Chao, XJ; Chen, ZW; Cui, W; Han, YF; He, XX; Kong, AN; Liu, AM; Liu, PQ; Mak, SH; Pi, RB; Ramassamy, C; Wang, SG; Wang, YT; Yu, ZL1

Other Studies

5 other study(ies) available for tacrine and caffeic acid

ArticleYear
Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2012, Oct-15, Volume: 22, Issue:20

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Butyrylcholinesterase; Caffeic Acids; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Hydrogen Peroxide; Mice; Neurons; Neuroprotective Agents; Tacrine

2012
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD.
    Bioorganic & medicinal chemistry letters, 2015, Feb-15, Volume: 25, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Caffeic Acids; Cell Line; Cholinesterase Inhibitors; Coumaric Acids; Drug Design; Humans; Models, Molecular; Structure-Activity Relationship; Tacrine; Thioctic Acid

2015
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Alzheimer Disease; Animals; Cinnamates; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycogen Synthase Kinase 3 beta; Molecular Structure; Stereoisomerism; Structure-Activity Relationship

2017
Polyphenolic compounds: Synthesis, assessment of antimicrobial effect and enzymes inhibition against important medicinal enzymes with computational details.
    Bioorganic & medicinal chemistry letters, 2022, 06-01, Volume: 65

    Topics: Acetylcholinesterase; Anti-Infective Agents; Antioxidants; Cholinesterase Inhibitors; Cholinesterases; Humans; Molecular Docking Simulation; Molecular Structure; Monophenol Monooxygenase; Structure-Activity Relationship

2022
Effect of tacrine-3-caffeic acid, a novel multifunctional anti-Alzheimer's dimer, against oxidative-stress-induced cell death in HT22 hippocampal neurons: involvement of Nrf2/HO-1 pathway.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Animals; Caffeic Acids; Cell Death; Cell Line, Transformed; Cytoskeletal Proteins; Glutamic Acid; Heme Oxygenase-1; Humans; Kelch-Like ECH-Associated Protein 1; Membrane Potential, Mitochondrial; Mice; Neurons; NF-E2-Related Factor 2; Nootropic Agents; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tacrine; Transfection

2014