tacrine has been researched along with atropine in 48 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (14.58) | 18.7374 |
1990's | 19 (39.58) | 18.2507 |
2000's | 13 (27.08) | 29.6817 |
2010's | 8 (16.67) | 24.3611 |
2020's | 1 (2.08) | 2.80 |
Authors | Studies |
---|---|
Chapman, JM; Kosh, JW; Sowell, JW; Tang, Y; Valli, MJ | 1 |
Chapman, JM; Kosh, JW; Sowell, JW; Tang, Y; Usher, LA; Valli, MJ; Vaughan, CM | 1 |
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Bard, B; Carrupt, PA; Martel, S | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Curtis, MA; Lin, SX; Sperry, J | 1 |
Bentley, GA; Wong, CL | 1 |
Mendelson, G | 1 |
Feuerstein, TJ; Jackisch, R; Lehmann, J; Sauermann, W; van Velthoven, V | 1 |
Menini, C; Rektor, I; Silva-Barrat, C; Svejdová, M | 1 |
Hroch, M | 1 |
Cecchini, L; Galli, A; Lucherini, M; Mazri, A; Mori, F | 1 |
Loiacono, RE; Mitchelson, FJ | 1 |
Drukarch, B; Kits, KS; Lodder, JC; Stoof, JC; Van der Meer, EG | 1 |
Hroch, M; Kolárová, J | 3 |
Cotman, CW; Stevens, DR | 1 |
Bagetta, G; Corasaniti, MT; Finazzi-Agrò, A; Melino, G; Nisticò, G; Paoletti, AM | 1 |
Gean, PW; Huang, CC; Wang, SJ | 1 |
Bagetta, G; Federici, G; Massoud, R; Nisticò, G; Rodinò, P | 1 |
Fujimoto, K; Kawashima, K; Nonaka, H; Suzuki, T | 1 |
Lau, WM | 1 |
Nordberg, A; Warpman, U; Zhang, X | 1 |
Farlow, MR; Lahiri, DK | 1 |
Nordberg, A; Svensson, AL; Zhang, X | 1 |
Dowling, MH; Paddle, BM | 1 |
Cavun, S; Gürün, MS; Savci, V; Ulus, IH | 2 |
Allal, C; Brefel-Courbon, C; Gharib, C; Lazartigues, E; Montastruc, JL; Rascol, O; Tran, MA | 1 |
Brefel-Courbon, C; Freslon, JL; Lazartigues, E; Montastruc, JL; Pelat, M; Rascol, O; Tellioglu, T; Tran, MA | 1 |
Han, YF; Pan, SY | 1 |
Bernard, V; Bloch, B; Liste, I | 1 |
Getova-Spassova, D; Krustev, A; Spassov, V; Turijski, V | 1 |
Bermudez, I; Groot-Kormelink, PJ; Smulders, CJ; van Kleef, RG; Vijverberg, HP; Zwart, R | 1 |
Haobam, R; Mehta, H; Mohanakumar, KP; Usha, R | 1 |
Cheng, K; Davis, RJ; Drachenberg, C; Nomikos, G; Raufman, JP; Samimi, R; Shant, J; Wade, M; Xie, G | 1 |
Hu, Y; Orsi, A; Rees, D; Wang, Z; Wu, P; Xia, Z; Zhang, R | 1 |
Goel, RK; Mishra, A | 1 |
1 review(s) available for tacrine and atropine
Article | Year |
---|---|
Pyridine alkaloids with activity in the central nervous system.
Topics: Alkaloids; Amphibians; Animals; Bacteria; Central Nervous System Diseases; Fungi; Nicotine; Plants; Pyridines; Receptors, Nicotinic | 2020 |
47 other study(ies) available for tacrine and atropine
Article | Year |
---|---|
Synthesis and cholinergic properties of N-aryl-2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethylamino analogs of ranitidine.
Topics: Acetylcholine; Animals; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Synergism; Erythrocytes; Humans; Ileum; Male; Mice; Muscle Contraction; Ranitidine; Rats; Receptors, Muscarinic | 1992 |
Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine.
Topics: Animals; Cholinesterase Inhibitors; Furans; Humans; Male; Mice; Parasympathomimetics; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship | 1992 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The effect of stress and adrenalectomy on morphine analgesia and naloxone potency in mice.
Topics: Adrenal Medulla; Adrenalectomy; Analgesia; Animals; Atropine; Corticosterone; Male; Mice; Morphine; Motor Activity; Muscle Contraction; Naloxone; Restraint, Physical; Stress, Physiological; Tacrine | 1979 |
Letter: Hallucinogenic plants.
Topics: Acridines; Atropine; Hallucinations; Humans; Orphenadrine; Plant Poisoning; Psychoses, Substance-Induced; Tacrine | 1975 |
The autoinhibitory feedback control of acetylcholine release in human neocortex tissue.
Topics: Acetylcholine; Aging; Atropine; Cerebral Cortex; Electric Stimulation; Feedback; Humans; In Vitro Techniques; Muscarinic Antagonists; Oxotremorine; Physostigmine; Receptors, Cholinergic; Tacrine | 1992 |
Unexpected potentializing effect of a tacrine derivative (9-amino-7-methoxy-1,2,3,4 tetrahydroacridine) upon the non-epileptic myoclonus in baboons Papio papio.
Topics: Animals; Atropine; Drug Synergism; Epilepsies, Myoclonic; Myoclonus; Papio; Physostigmine; Tacrine | 1990 |
[Induced cell fusion in the contact zone of cells with affected and unaffected surfaces. I].
Topics: Atropine; Cell Fusion; Cell Membrane; Polyethylene Glycols; Quinuclidinyl Benzilate; Tacrine | 1990 |
Prevention of diisopropylfluorophosphate (DFP)-induced lethality by meptazinol and 9-amino-tetrahydroacridine (THA) in the mouse.
Topics: Acetylcholinesterase; Aminoacridines; Animals; Atropine; Azepines; Brain; In Vitro Techniques; Isoflurophate; Meptazinol; Mice; Respiratory Muscles; Tacrine | 1990 |
Effect of nicotine and tacrine on acetylcholine release from rat cerebral cortical slices.
Topics: Acetylcholine; Aminoacridines; Animals; Atropine; Cerebral Cortex; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Male; Nerve Endings; Nicotine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Tacrine; Tubocurarine | 1990 |
9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ current.
Topics: Alzheimer Disease; Aminoacridines; Animals; Atropine; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Electrophysiology; In Vitro Techniques; Ion Channels; Lymnaea; Male; Oxotremorine; Physostigmine; Rats; Rats, Inbred Strains; Tacrine | 1987 |
[The effect of atropine, quinuclidinyl benzilate and their antidote tetrahydroaminoacridine on adhesion and spreading in cells cultured in vitro].
Topics: Aminoacridines; Animals; Antidotes; Atropine; Cell Adhesion; L Cells; Mice; Quinuclidines; Quinuclidinyl Benzilate; Tacrine | 1988 |
[The effect of tetrahydroaminoacridine on the toxic effects of atropine in cells cultured in vitro. II].
Topics: Aminoacridines; Animals; Atropine; L Cells; Mice; Tacrine | 1987 |
Excitatory actions of tetrahydro-9-aminoacridine (THA) on hippocampal pyramidal neurons.
Topics: Action Potentials; Aminoacridines; Animals; Atropine; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Tacrine; Tetrodotoxin | 1987 |
[Study of the toxic effects of atropine and the effect of tetrahydroaminoacrine on cells cultured in vitro. I].
Topics: Aminoacridines; Atropine; Cell Line; Cell Survival; Quinuclidinyl Benzilate; Tacrine | 1985 |
Lithium and tacrine increase the expression of nitric oxide synthase mRNA in the hippocampus of rat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Cerebral Ventricles; Corticosterone; DNA Probes; Gene Expression; Hippocampus; Injections, Intraventricular; Kinetics; Lithium Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; RNA, Messenger; Tacrine | 1993 |
Tetrahydro-9-aminoacridine presynaptically inhibits glutamatergic transmission in the rat amygdala.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Atropine; Electric Stimulation; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Synaptic Transmission; Tacrine | 1995 |
Systemic administration of lithium chloride and tacrine increases nitric oxide synthase activity in the hippocampus of rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Cerebral Cortex; Chlorides; Cyclic GMP; Hippocampus; Lithium; Lithium Chloride; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Seizures; Tacrine | 1993 |
Tacrine increases stimulation-evoked acetylcholine release from rat hippocampal slices.
Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Physostigmine; Rats; Tacrine | 1994 |
Protection by tacrine and some adjuncts against the depressant effects of soman in guinea-pig atrium.
Topics: Animals; Atropine; Cholinesterase Reactivators; Female; Glycopyrrolate; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Oximes; Parasympatholytics; Pyridinium Compounds; Soman; Tacrine | 1993 |
Effect of tacrine on in vivo release of dopamine and its metabolites in the striatum of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atropine; Cholinesterase Inhibitors; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mecamylamine; Microdialysis; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Nicotinic; Tacrine | 1996 |
Differential effect of tacrine and physostigmine on the secretion of the beta-amyloid precursor protein in cell lines.
Topics: Amyloid beta-Protein Precursor; Animals; Arecoline; Astrocytes; Atropine; Calcimycin; Carbachol; Cholinesterase Inhibitors; Enzyme Inhibitors; HeLa Cells; Humans; Ionophores; Muscarinic Agonists; Muscarinic Antagonists; Neuroblastoma; PC12 Cells; Physostigmine; Rats; Staurosporine; Tacrine | 1996 |
Biphasic effect of tacrine on acetylcholine release in rat brain via M1 and M2 receptors.
Topics: Acetylcholine; Alzheimer Disease; Analysis of Variance; Animals; Atropine; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Synaptosomes; Tacrine | 1996 |
Blockade of cardiac nicotinic responses by anticholinesterases.
Topics: Acetylcholine; Animals; Atropine; Carbamates; Catecholamines; Cholinesterase Inhibitors; Edrophonium; Female; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Myocardial Contraction; Nicotine; Nicotinic Antagonists; Soman; Tacrine | 1996 |
Cardiovascular effects of centrally injected tetrahydroaminoacridine in conscious normotensive rats.
Topics: Animals; Atropine; Blood Pressure; Cholinesterase Inhibitors; Epinephrine; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Renin; Tacrine; Vasopressins | 1998 |
Central cardiovascular effects of tacrine in the conscious dog: a role for catecholamines and vasopressin release.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cholinesterase Inhibitors; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Injections, Intravenous; Male; Muscarinic Antagonists; N-Methylscopolamine; Norepinephrine; Parasympathomimetics; Receptors, Muscarinic; Tacrine; Vasopressins | 1998 |
Pressor and bradycardic effects of tacrine and other acetylcholinesterase inhibitors in the rat.
Topics: Adrenergic Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Atropine; Atropine Derivatives; Blood Pressure; Carbamates; Cardiovascular Agents; Chlorisondamine; Cholinergic Antagonists; Cholinesterase Inhibitors; Diamines; Diastole; Dose-Response Relationship, Drug; Heart Rate; Male; Phenylcarbamates; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Rivastigmine; Systole; Tacrine | 1998 |
Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Intravenous; Animals; Antidiuretic Hormone Receptor Antagonists; Atropine; Blood Pressure; Cardiovascular Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Epinephrine; Female; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Mecamylamine; Norepinephrine; Prazosin; Rats; Rats, Wistar; Renin; Shock, Hemorrhagic; Survival Analysis; Tacrine; Time Factors; Urethane; Vasopressins | 2001 |
Learning deficits induced by 4 belladonna alkaloids are preferentially attenuated by tacrine.
Topics: Animals; Atropine; Avoidance Learning; Cholinesterase Inhibitors; Learning Disabilities; Male; Mice; Motor Activity; Muscarinic Antagonists; Retention, Psychology; Scopolamine; Scopolamine Derivatives; Solanaceous Alkaloids; Tacrine | 2000 |
Acute and chronic acetylcholinesterase inhibition regulates in vivo the localization and abundance of muscarinic receptors m2 and m4 at the cell surface and in the cytoplasm of striatal neurons.
Topics: Acetylcholinesterase; Animals; Atropine; Cell Membrane; Cholinesterase Inhibitors; Cytoplasm; Dendrites; Drug Administration Schedule; Immunohistochemistry; Male; Microscopy, Electron; Muscarinic Antagonists; Neostriatum; Neurons; Organelles; Physostigmine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; RNA, Messenger; Tacrine; Trichlorfon; Up-Regulation | 2002 |
Influence of tacrine on dopamine-induced reactions of the gastric smooth muscle of rats.
Topics: Animals; Atropine; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Therapy, Combination; Haloperidol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Raclopride; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Dopamine D2; Stomach; Tacrine; Time Factors | 2004 |
Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Azocines; Binding, Competitive; Cholinergic Agents; Cholinesterase Inhibitors; Dichlorvos; Dose-Response Relationship, Drug; Female; Galantamine; Humans; Membrane Potentials; Models, Biological; Nicotine; Oocytes; Phenylcarbamates; Physostigmine; Plasmids; Quinolizines; Receptors, Nicotinic; Rivastigmine; Scopolamine; Tacrine; Xenopus laevis | 2005 |
Evidence for the involvement of central serotonergic mechanisms in cholinergic tremor induced by tacrine in Balb/c mice.
Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Behavior, Animal; Biogenic Amines; Brain; Brain Chemistry; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Serotonin; Serotonin Antagonists; Tacrine; Time Factors; Tremor | 2005 |
Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation.
Topics: Acetylcholine; Acetylcholinesterase; Atropine; Autocrine Communication; Caco-2 Cells; Cell Proliferation; Choline; Choline O-Acetyltransferase; Cholinergic Agents; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dose-Response Relationship, Drug; Electrochemistry; Hemicholinium 3; HT29 Cells; Humans; Immunohistochemistry; Membrane Transport Proteins; Muscarinic Antagonists; Physostigmine; Piperidines; Polymerase Chain Reaction; Receptor, Muscarinic M3; RNA, Messenger; Tacrine | 2008 |
Regulation of M1-receptor mRNA stability by smilagenin and its significance in improving memory of aged rats.
Topics: 3,3'-Diaminobenzidine; Aging; Analysis of Variance; Animals; Atropine; Binding Sites; Binding, Competitive; Brain; CHO Cells; Cholinesterase Inhibitors; Cholinesterases; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Maze Learning; Memory Disorders; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; RNA, Messenger; Spirostans; Tacrine; Transfection; Tritium | 2010 |
Adjuvant anticholinesterase therapy for the management of epilepsy-induced memory deficit: a critical pre-clinical study.
Topics: Animals; Anticonvulsants; Atropine; Chemotherapy, Adjuvant; Cholinesterase Inhibitors; Epilepsy; Male; Maze Learning; Memory Disorders; Mice; Nootropic Agents; Phenytoin; Tacrine | 2014 |