tacrine has been researched along with ascorbic acid in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Agrawal, N; Machhi, J; Murumkar, P; Parikh, Z; Pillai, P; Sharma, MK; Shidore, M; Shingala, K; Tripathi, A; Yadav, MR | 1 |
| Bachurin, SO; Boltneva, NP; Burgart, YV; Chupakhin, ON; Kovaleva, NV; Lushchekina, SV; Makhaeva, GF; Richardson, RJ; Rudakova, EV; Saloutin, VI; Serebryakova, OG; Shchegol'kov, EV | 1 |
| Artym, J; Jeleń, M; Kocięba, M; Morak-Młodawska, B; Pluta, K; Zaczyńska, E; Zimecki, M | 1 |
| Beloglazkin, AA; Boltneva, NP; Borisov, RS; Kulikova, LN; Lushchekina, SV; Makhaeva, GF; Richardson, RJ; Rudakova, EV; Serebryakova, OG | 1 |
| Han, J; Ji, L; Li, Z; Ma, J; Wang, M; Wu, M | 1 |
| Ju, H; Kou, X; Shen, R; Song, L; Wang, Y; Yang, A; Yu, Q | 1 |
| Ju, H; Kou, X; Shen, R; Wu, J; Yang, A; Zhang, H | 1 |
| Madden, S; Park, BK; Pool, WF; Woolf, TF | 1 |
1 review(s) available for tacrine and ascorbic acid
| Article | Year |
|---|---|
Azaphenothiazines - promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Antipsychotic Agents; Bacteria; Fungi; Humans; Leishmania; Molecular Structure; Neoplasms; Phenothiazines | 2017 |
9 other study(ies) available for tacrine and ascorbic acid
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Benzylpiperidine-Linked Diarylthiazoles as Potential Anti-Alzheimer's Agents: Synthesis and Biological Evaluation.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Butyrylcholinesterase; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Male; Mice; Molecular Structure; Piperidines; Rats; Rats, Wistar; Reactive Oxygen Species; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 2016 |
Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors.
Topics: Animals; Carboxylesterase; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Structure-Activity Relationship; Triazines | 2017 |
Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics.
Topics: Acetylcholinesterase; Alzheimer Disease; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Chromones; Humans; Kinetics; Molecular Docking Simulation; Protein Structure, Tertiary; Structure-Activity Relationship | 2018 |
Design, synthesis, and biological evaluation of rutacecarpine derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Line, Tumor; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protective Agents; Protein Multimerization; Rats; Structure-Activity Relationship; Sulfonamides | 2019 |
Design, synthesis and anti-Alzheimer's disease activity study of xanthone derivatives based on multi-target strategy.
Topics: Acetylcholinesterase; Alzheimer Disease; Antioxidants; Binding Sites; Catalytic Domain; Cholinesterase Inhibitors; Drug Design; Humans; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship; Xanthones | 2020 |
Design, synthesis and biological evaluation of naringenin carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Carbamates; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Electrophorus; Flavanones; Free Radical Scavengers; Horses; Kinetics; Molecular Docking Simulation; Molecular Structure; Peptide Fragments; Protein Binding; Protein Multimerization; Structure-Activity Relationship | 2021 |
An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro. Studies with human and rat liver microsomes.
Topics: Adult; Animals; Ascorbic Acid; Biotransformation; Cell Death; Enoxacin; Glutathione; Humans; Lymphocytes; Male; Microsomes, Liver; NADP; Rats; Tacrine | 1993 |