tacrine has been researched along with ambenonium in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A | 1 |
| Cappa, A; Carotti, A; Catto, M; Leonetti, F; Nicolotti, O; Pisani, L; Stefanachi, A | 1 |
| Al-Rashid, ZF; Beri, V; Cheung, J; Rosenberry, TL; Shiomi, K; Wildman, SA | 1 |
3 other study(ies) available for tacrine and ambenonium
| Article | Year |
|---|---|
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine | 2008 |
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Computer Simulation; Drug Design; Edrophonium; Horses; Models, Molecular; Molecular Structure; Protein Binding; Structure-Activity Relationship | 2008 |
The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.
Topics: Acetylcholine; Acetylcholinesterase; Aflatoxin B1; Binding Sites; Binding, Competitive; Catalysis; Catalytic Domain; Cholinesterase Inhibitors; Crystallography, X-Ray; Furans; Humans; Hydrolysis; Kinetics; Models, Chemical; Phenanthrenes; Pyrans; Quinones; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2013 |