tacrine and acridines

tacrine has been researched along with acridines in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (74.58)	18.7374
1990's	3 (5.08)	18.2507
2000's	1 (1.69)	29.6817
2010's	10 (16.95)	24.3611
2020's	1 (1.69)	2.80

Authors

Authors	Studies
Calil, HM; Hollister, LE; Nakano, S	1
Crul, JF; Martinez-Aguirre, E	1
Bajgar, J; Fusek, J; Hrdina, V; Patocka, J	1
Fusek, J; Hrdina, V; Koupilová, M	3
Bajgar, J; Fusek, J; Herink, J; Hrdina, V; Koupilová, M; Patocka, J	2
Bajgar, J; Fusek, J; Herink, J; Hrdina, V; Patocka, J	1
Albin, MS	1
Mendelson, G	6
Papaphilis, AD; Shaw, YH	1
Morgan, M; Norman, J	1
Padinker, EB; Tonkopiĭ, VD	1
Davis, M; Jones, CR	1
el-Gafi, SH; el-Kammah, BM; el-Sherbiny, AM; Kader, MM	1
Butterfield, DA; Rangachari, A	1
Albin, RL; Penney, JB; Young, AB	1
Dhawan, BN; Gupta, PP; Phadke, VK; Rajauria, SS; Singh, D; Singhal, AP; Suri, YV	1
Bhalerao, RA; Mody, BB; Paul, T; Samsi, AB; Satoskar, RS; Shah, SC	1
Dasgupta, D; Garasia, M; Gupta, KC; Satoskar, RS	1
Davis, KL; Hsieh, JY; Yang, RK	1
Altman, F; Fischer, JM; Kaufman, KR; Summers, WK	1
Anand, N; Dhawan, BN; Patnaik, GK; Rastogi, SN	1
Dhawan, BN; Patnaik, GK	1
Mukherjee, SK; Nityanand, S; Roy, AK; Sethi, N; Srivastava, GN	1
Mukherjee, SK; Sethi, N	1
Dhawan, BN; Gupta, PP; Nityanand, S; Shipstone, AC	1
Dhawan, BN; Gupta, PP; Saxena, RC; Tangri, AN	1
Candelora, K; Marsh, GM; Summers, WK; Viesselman, JO	1
Atallah, MM; El-Bana, MH; El-Hawary, KA; Hussein, SM; Wafa, AM	1
Chau, JH; Chen, J; Pirrung, MC	1
Borisova, AO; Burov, IuV; Goncharenko, SB; Robakidze, TN	1
BENVENISTE, D; DYRBERG, V	1
DYRBERG, V; HOUGS, W; JOHANSEN, SH	1
SMART, JF	1
BRIAN, WP; SOUTHER, BL	1
BLEIBERG, MJ	1
KAUL, PN	2
Gong, T; Huang, Y; Li, LL; Zhang, ZR	1
Dohnal, V; Fisar, Z; Holas, O; Hroudova, J; Jun, D; Korabecny, J; Kuca, K; Musilek, K; Nachon, F; Nepovimova, E; Opletalova, V; Patocka, J; Zemek, F	1
Karpiński, A; Mikiciuk-Olasik, E; Szymanski, P	1
Markowicz, M; Mikiciuk-Olasik, E; Szymański, P	1
Fisar, Z; Holas, O; Horova, A; Hroudova, J; Jung, YS; Korabecny, J; Kuca, K; Musilek, K; Nepovimova, E; Opletalova, V; Zemek, F	1
Cui, Y; Gu, J; Liang, Y; Wang, D; Xu, J; Zhang, D; Zhao, X	1
Hao, GF; Yang, GF; Yang, WC; Yu, NX; Zhu, XL	1
Guo, DS; Liu, Y; Yang, J	1
VAN DE WAL, A	1
Böhm, S; Danihel, I; Hamulakova, S; Holas, O; Imrich, J; Janovec, L; Kozurkova, M; Kristian, P; Kuca, K; Pohanka, M	1
Chufarova, N; Cuchra, M; Czarnecka, K; Majsterek, I; Skibiński, R; Szymański, P	1
Babkova, K; Brabec, V; Fedorocko, P; Hamulakova, S; Janockova, J; Jendzelovsky, R; Kasparkova, J; Konkolova, E; Korabecny, J; Koval, J; Kozurkova, M; Kuca, K; Kucerova, D; Plsikova, J; Rosocha, J; Soukup, O; Vargova, J	1
Askari, N; Fathi Hafshejani, S; Hatami, M; Kermani, ET; Lotfi, S; Mortazavi, M; Pouramiri, B; Pourjamali, N; Rahmani, T; Rezvannejad, E; Zahedifar, M	1

Reviews

1 review(s) available for tacrine and acridines

Article	Year
THA--a review of the literature and its use in treatment of five overdose patients. Clinical toxicology, 1980, Volume: 16, Issue:3 Topics: Acridines; Adolescent; Adult; Central Nervous System Agents; Female; Humans; Male; Tacrine; Time Factors	1980

Trials

3 trial(s) available for tacrine and acridines

Article	Year
Double blind study on centbucridine for subarachnoid and extradural anaesthesia. The Indian journal of medical research, 1982, Volume: 76 Topics: Acridines; Adolescent; Adult; Aged; Anesthesia, Epidural; Blood Pressure; Child; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Pulse; Respiration; Tacrine	1982
Randomised double-blind study of centbucridine and lignocaine for subarachnoid block. The Indian journal of medical research, 1983, Volume: 77 Topics: Acridines; Adolescent; Adult; Aged; Anesthesia, Spinal; Double-Blind Method; Humans; Lidocaine; Male; Middle Aged; Random Allocation; Spinal Nerves; Subarachnoid Space; Tacrine	1983
A single-center, randomized, open-label, dose-escalation study to evaluate the pharmacokinetics of tacrine analogue octahydrogenacridine succinate tablets in healthy Chinese subjects. Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:9 Topics: Acridines; Adult; Aged; Alzheimer Disease; China; Dose-Response Relationship, Drug; Female; Humans; Intestinal Absorption; Male; Reference Values; Succinates; Tablets; Tacrine	2012

Other Studies

55 other study(ies) available for tacrine and acridines

Article	Year
Effects of 5-hydroxytryptophan, oxotermorine, and tetrahydroaminoacridine on apomorphine-induced stereotypy. Psychopharmacology, 1978, Jun-15, Volume: 58, Issue:1 Topics: 5-Hydroxytryptophan; Acridines; Animals; Apomorphine; Behavior; Humans; Male; Oxotremorine; Rats; Stereotyped Behavior; Tacrine; Time Factors	1978
Effect of tetrahydroaminoacridine and 4-aminopyridine on recovery from ketamine-diazepam anesthesia in the macacus rhesus monkey. Acta anaesthesiologica Belgica, 1979, Volume: 30, Issue:4 Topics: 4-Aminopyridine; Acridines; Aminopyridines; Anesthesia, Intravenous; Animals; Diazepam; Electroencephalography; Haplorhini; Ketamine; Macaca mulatta; Tacrine	1979
In vivo kinetics of blood cholinesterase inhibition by 9-amino-1, 2, 3, 4-tetrahydroacridine, its 7-methoxy derivative and physostigmine in rats. Physiologia Bohemoslovaca, 1979, Volume: 28, Issue:1 Topics: Acetylcholinesterase; Acridines; Animals; Kinetics; Male; Physostigmine; Rats; Tacrine	1979
[Inhibition of human and animal plasma esterase isoenzymes using Tacrin (1, 2, 3, 4-tetrahydro-9-aminoacridine)]. Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum, 1977, Volume: 20, Issue:2-3 Topics: Acridines; Animals; Esterases; Humans; Isoenzymes; Mice; Rats; Tacrine	1977
Diazepam in combination with tacrine derivatives antagonizes behavioural effects of anticholinergic psychotomimetics in rats. Activitas nervosa superior, 1979, Volume: 21, Issue:3 Topics: Acridines; Animals; Conditioning, Classical; Conditioning, Operant; Diazepam; Exploratory Behavior; Hallucinogens; Motor Skills; Parasympatholytics; Rats; Tacrine	1979
The interaction of anticholinesterases and diazepam in the treatment of anticholinergic syndrome in dogs. Activitas nervosa superior, 1979, Volume: 21, Issue:3 Topics: Acridines; Animals; Diazepam; Dogs; Drug Combinations; Quinuclidines; Quinuclidinyl Benzilate; Syndrome; Tacrine	1979
Tacrine and its derivatives antagonize cholinergic psychotomimetics. Behavioural study in rats. Activitas nervosa superior, 1978, Volume: 20, Issue:1 Topics: Acridines; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Hallucinogens; Male; Motor Activity; Rats; Receptors, Cholinergic; Tacrine	1978
Interaction of imipramine and 3-quinuclidyl benzilate with 9-amino-7-methoxy-1,2,3,4-tetrahydroacridine on the after-discharges in the limbic system. Activitas nervosa superior, 1978, Volume: 20, Issue:1 Topics: Acridines; Animals; Benzilates; Drug Interactions; Evoked Potentials; Imipramine; Limbic System; Male; Quinuclidines; Rats; Tacrine	1978
Experimental therapy of poisoning with anticholinergic drugs in dogs. Activitas nervosa superior, 1978, Volume: 20, Issue:1 Topics: Acridines; Animals; Autonomic Nervous System; Behavior, Animal; Dogs; Motor Activity; Parasympatholytics; Tacrine	1978
Tetrahydroaminoacridine and phencyclidine intoxication. JAMA, 1978, Aug-11, Volume: 240, Issue:6 Topics: Acridines; Animals; Humans; Phencyclidine; Substance-Related Disorders; Tacrine; United States; United States Food and Drug Administration	1978
Pheniramine aminosalicylate overdosage. Reversal of delirium and choreiform movements with tacrine treatment. Archives of neurology, 1977, Volume: 34, Issue:5 Topics: Acridines; Adolescent; Chorea; Delirium; Female; Humans; Pheniramine; Substance-Related Disorders; Tacrine	1977
Interaction of acridines and tetrahydroacridines with DNA at low DNA/dye ratios. Biochimica et biophysica acta, 1977, May-17, Volume: 476, Issue:2 Topics: Acridines; Animals; Cattle; Chemical Phenomena; Chemistry; DNA; Kinetics; Ligands; Proflavine; Tacrine; Thymus Gland	1977
Letter: Treatment of hallucinogenic-plant toxicity. Annals of internal medicine, 1976, Volume: 85, Issue:1 Topics: Acridines; Antidotes; Autonomic Nervous System; Datura stramonium; Hallucinogens; Humans; Physostigmine; Plant Poisoning; Plants, Medicinal; Plants, Toxic; Tacrine	1976
Accidental poisoning: pheniramine. The Medical journal of Australia, 1976, Jul-17, Volume: 2, Issue:3 Topics: Acridines; Adolescent; Female; Humans; Pheniramine; Tacrine	1976
Letter: Hallucinogenic plants. The Medical journal of Australia, 1975, Jun-28, Volume: 1, Issue:26 Topics: Acridines; Atropine; Hallucinations; Humans; Orphenadrine; Plant Poisoning; Psychoses, Substance-Induced; Tacrine	1975
Letter: Antidotes for drug overdose. Anaesthesia and intensive care, 1975, Volume: 3, Issue:3 Topics: Acridines; Humans; Orphenadrine; Physostigmine; Tacrine	1975
Proceedings: The effect of tacrine on the neuromuscular block produced by suxamethonium in man. British journal of anaesthesia, 1975, Volume: 47, Issue:9 Topics: Acridines; Drug Synergism; Humans; Nerve Block; Neuromuscular Junction; Succinylcholine; Tacrine	1975
[Effect of reversible inhibitors on the thermal denaturation of cholinesterases]. Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 79, Issue:4 Topics: Acridines; Animals; Brain; Cholinesterases; Galantamine; Hot Temperature; Mice; Molecular Conformation; Rats; Tacrine	1975
Letter: Replacement drug for edrophonium bromide. The Medical journal of Australia, 1975, Oct-18, Volume: 2, Issue:16 Topics: Acridines; Adult; Cholinesterase Inhibitors; Edrophonium; Female; Humans; Myasthenia Gravis; Quaternary Ammonium Compounds; Tacrine	1975
Central anticholinergic syndrome reversed by tetrahydroaminacrine (tha). The Medical journal of Australia, 1975, Dec-13, Volume: 2, Issue:24 Topics: Acridines; Adolescent; Humans; Orphenadrine; Psychoses, Substance-Induced; Syndrome; Tacrine	1975
Biochemical and clinical study for the role of tacrine as succinylcholine extender. The Journal of the Egyptian Medical Association, 1975, Volume: 58, Issue:9-10 Topics: Acridines; Adult; Aged; Cholinesterase Inhibitors; Drug Synergism; Female; Humans; Male; Middle Aged; Succinylcholine; Tacrine	1975
Membrane-altering effects of velnacrine and N-methylacridinium: relevance to tacrine and Alzheimer's disease. Biochemical and biophysical research communications, 1992, Jun-15, Volume: 185, Issue:2 Topics: Acridines; Alzheimer Disease; Cytoskeletal Proteins; Cytoskeleton; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; In Vitro Techniques; Protein Binding; Structure-Activity Relationship; Tacrine	1992
Tetrahydro-9-aminoacridine (THA) interacts with the phencyclidine (PCP) receptor site. Neuroscience letters, 1988, Jun-07, Volume: 88, Issue:3 Topics: Acridines; Aminoacridines; Aminopyridines; Animals; Binding, Competitive; Cholinesterase Inhibitors; Frontal Lobe; Kinetics; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Tacrine	1988
Evaluation of centbucridine as a local anesthetic. Anesthesia and analgesia, 1983, Volume: 62, Issue:1 Topics: Acridines; Adult; Anesthetics, Local; Blood Pressure; Double-Blind Method; Drug Evaluation; Female; Humans; Lidocaine; Male; Middle Aged; Random Allocation; Tacrine	1983
High-performance liquid chromatographic determination of tetrahydroaminoacridine in human and rat tissues using a rapid Sep-Pak C18 extraction. Journal of chromatography, 1983, May-13, Volume: 274 Topics: Acridines; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Humans; Male; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Tacrine	1983
Evaluation of local anaesthetic activity of 4-N-butylamino-1,2,3,4-tetrahydroacridine hydrochloride (Centbucridine)--a 4-substituted polymethylenequinoline. Indian journal of experimental biology, 1982, Volume: 20, Issue:4 Topics: Acridines; Anesthetics, Local; Animals; Cats; Dogs; Drug Evaluation; Female; Guinea Pigs; Irritants; Lidocaine; Male; Rabbits; Tacrine	1982
Pharmacological study of 4-N-butylamino-1,2,3,4-tetrahydroacridine hydrochloride (Centbucridine)--a new local anaesthetic agent. Indian journal of experimental biology, 1982, Volume: 20, Issue:4 Topics: Acridines; Anesthetics, Local; Animals; Cats; Female; Guinea Pigs; Lidocaine; Macaca mulatta; Male; Mice; Rabbits; Rats; Tacrine	1982
Chronic toxicity studies on 4-N-butylamino-1,2,3,4-tetrahydroacridine hydrochloride (Centbucridine)--a new local anaesthetic agent. Indian journal of experimental biology, 1982, Volume: 20, Issue:4 Topics: Acridines; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Macaca mulatta; Male; Rats; Rats, Inbred Strains; Tacrine; Time Factors	1982
Teratogenic studies on 4-N-butylamino-1,2,3,4-tetrahydroacridine hydrochloride (Centbucridine)--a new local anaesthetic agent. Indian journal of experimental biology, 1982, Volume: 20, Issue:4 Topics: Abnormalities, Drug-Induced; Acridines; Anesthetics, Local; Animals; Female; Mice; Pregnancy; Rabbits; Tacrine	1982
Experimental evaluation of potential neurotoxicity of 4-N-butylamino 1,2,3,4-tetrahydroacridine hydrochloride (Centbucridine)--a new local anaesthetic agent. Indian journal of experimental biology, 1982, Volume: 20, Issue:4 Topics: Acridines; Anesthesia, Spinal; Anesthetics, Local; Animals; Female; Male; Rabbits; Spinal Cord; Tacrine	1982
Clinical pharmacology studies on 4-N-butylamino-1,2,3,4-tetrahydroacridine hydrochloride (Centbucridine)--a new local anaesthetic agent. Indian journal of experimental biology, 1982, Volume: 20, Issue:4 Topics: Acridines; Adult; Anesthetics, Local; Humans; Injections, Intradermal; Injections, Intramuscular; Male; Middle Aged; Tacrine	1982
Use of THA in treatment of Alzheimer-like dementia: pilot study in twelve patients. Biological psychiatry, 1981, Volume: 16, Issue:2 Topics: Acridines; Adult; Aged; Alzheimer Disease; Dementia; Drug Evaluation; Female; Humans; Male; Memory; Middle Aged; Pilot Projects; Receptors, Cholinergic; Tacrine	1981
Tacrine-suxamethonium apnea in patients with hepatosplenic schistosomiasis. Middle East journal of anaesthesiology, 1980, Volume: 5, Issue:8 Topics: Acridines; Adolescent; Adult; Anesthesia; Cholinesterases; Drug Synergism; Humans; Liver Diseases, Parasitic; Male; Respiration; Schistosomiasis; Splenic Diseases; Succinylcholine; Tacrine; Time Factors	1980
Exploitation of the antagonistic properties of some drugs against poisoning with psychochemicals. Activitas nervosa superior, 1981, Volume: 23, Issue:4 Topics: Acridines; Animals; Female; Motor Activity; Parasympatholytics; Psychotropic Drugs; Rats; Rats, Inbred Strains; Tacrine	1981
Discovery of a novel tetrahydroacridine acetylcholinesterase inhibitor through an indexed combinatorial library. Chemistry & biology, 1995, Volume: 2, Issue:9 Topics: Acridines; Animals; Cholinesterase Inhibitors; Electrophorus; Kinetics; Spectrophotometry, Ultraviolet; Tacrine	1995
[Effect of the new 9-aminoacridine derivative on the working and long-term memory in rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:2 Topics: Acridines; Aminoquinolines; Amnesia; Animals; Cholinesterase Inhibitors; Learning; Male; Memory; Nootropic Agents; Rats; Scopolamine; Tacrine	1999
Tetrahydroaminoacridine. Clinical use of a cholinesterase inhibitor in conjunction with succinylcholine. Acta anaesthesiologica Scandinavica, 1962, Volume: 6 Topics: Acridines; Anesthesia; Anesthesiology; Cholinesterase Inhibitors; Humans; Succinylcholine; Tacrine	1962
Hydroaminacrine. I. Its influence on the interaction of edrophonium and suxamethonium. Acta pharmacologica et toxicologica, 1962, Volume: 19 Topics: Acridines; Edrophonium; Leadership; Succinylcholine; Tacrine	1962
POTENTIATION OF SUXAMETHONIUM BY TACRINE (ROMOTAL). Anaesthesia, 1964, Volume: 19 Topics: Acridines; Biomedical Research; Electromyography; Humans; Pharmacology; Succinylcholine; Tacrine	1964
NEW DERIVATIVES OF 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE. Journal of medicinal chemistry, 1965, Volume: 8 Topics: Acridines; Chemistry, Pharmaceutical; Research; Tacrine	1965
STRUCTURE-ACTIVITY RELATIONSHIPS FOR INTESTINAL STIMULATION BY TETRAHYDROAMINOACRIDINE (THA) AND 9-ALKYL THA HOMOLOGUES. Life sciences (1962), 1965, Volume: 4 Topics: Acetylcholine; Acridines; Arthroplasty, Replacement, Hip; Ileum; Intestine, Small; Intestines; Methacholine Compounds; Muscle, Smooth; Nicotine; Pharmacology; Rabbits; Research; Salicylates; Structure-Activity Relationship; Tacrine	1965
Enzyme inhibiting action of tetrahydroaminoacridine and its structural fragments. The Journal of pharmacy and pharmacology, 1962, Volume: 14 Topics: Acridines; Cholinesterase Inhibitors; Monoamine Oxidase Inhibitors; Tacrine	1962
Estimation and urinary excretion of tetrahydroaminoacridine. The Journal of pharmacy and pharmacology, 1962, Volume: 14 Topics: Acridines; Humans; Regression Analysis; Tacrine	1962
Synthesis and characterization of 9-[P-(N, N-dipropyl sulfamide)] benzoylamino-1,2,3,4-4H-acridine--a potential prodrug for the CNS delivery of tacrine. Journal of drug targeting, 2004, Volume: 12, Issue:3 Topics: Acridines; Animals; Biological Transport; Blood-Brain Barrier; Brain; Buffers; Chromatography, High Pressure Liquid; Drug Stability; In Vitro Techniques; Injections, Intravenous; Mice; Prodrugs; Solubility; Sulfonamides; Tacrine; Time Factors; Tissue Distribution	2004
Synthesis and in vitro evaluation of N-(Bromobut-3-en-2-yl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine as a cholinesterase inhibitor with regard to Alzheimer's disease treatment. Molecules (Basel, Switzerland), 2010, Dec-02, Volume: 15, Issue:12 Topics: Acridines; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Drug Evaluation, Preclinical; Heterocyclic Compounds, 3-Ring; Humans; Tacrine	2010
Synthesis, biological activity and HPLC validation of 1,2,3,4-tetrahydroacridine derivatives as acetylcholinesterase inhibitors. European journal of medicinal chemistry, 2011, Volume: 46, Issue:8 Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Benzoates; Butyrylcholinesterase; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Drug Stability; Enzyme Activation; Humans; Hydrolysis; Kinetics; Limit of Detection; Oxidation-Reduction; Sensitivity and Specificity; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tacrine	2011
Synthesis and biological activity of derivatives of tetrahydroacridine as acetylcholinesterase inhibitors. Bioorganic chemistry, 2011, Volume: 39, Issue:4 Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Cholinesterase Inhibitors; Enzyme Activation; Humans; Kinetics; Niacin; Tacrine	2011
Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties. Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21 Topics: Acridines; Cholinergic Agents; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Half-Life; In Vitro Techniques; Models, Molecular; Tacrine	2011
Structural basis of femtomolar inhibitors for acetylcholinesterase subtype selectivity: insights from computational simulations. Journal of molecular graphics & modelling, 2013, Volume: 41 Topics: Acetylcholinesterase; Acridines; Animals; Binding Sites; Cholinesterase Inhibitors; Drosophila melanogaster; Isoenzymes; Mice; Molecular Dynamics Simulation; Phenanthridines; Protein Binding; Structure-Activity Relationship; Tacrine; Thermodynamics; Torpedo; Triazoles	2013
Specifically monitoring butyrylcholinesterase by supramolecular tandem assay. Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Jul-01, Volume: 19, Issue:27 Topics: Acridines; Butyrylcholinesterase; Calixarenes; Cholinesterase Inhibitors; Enzyme Assays; Fluorescent Dyes; Neuromuscular Agents; Succinylcholine; Tacrine	2013
The acute intravenous toxicity of tetrahydroaminoacridine. Technical report. CRDLR. US Army Edgewood Arsenal Chemical Research and Development Laboratories, 1961, Volume: 3042 Topics: Acridines; Administration, Intravenous; Humans; Tacrine	1961
Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers. International journal of biological macromolecules, 2014, Volume: 70 Topics: Acetylcholinesterase; Acridines; Butyrylcholinesterase; Cholinesterase Inhibitors; Enzyme Activation; Humans; Models, Molecular; Molecular Conformation; Piperazine; Piperazines; Protein Binding; Tacrine; Thiourea	2014
New tacrine-acridine hybrids as promising multifunctional drugs for potential treatment of Alzheimer's disease. Archiv der Pharmazie, 2018, Volume: 351, Issue:7 Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Amyloid beta-Peptides; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Computer Simulation; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship; Tacrine	2018
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers. Journal of enzyme inhibition and medicinal chemistry, 2019, Volume: 34, Issue:1 Topics: A549 Cells; Acridines; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; HL-60 Cells; Humans; Structure-Activity Relationship; Tacrine; Thiourea	2019
Design, synthesis and biological assessment of acridine derivatives containing 1,3,4-thiadiazole moiety as novel selective acetylcholinesterase inhibitors. Bioorganic chemistry, 2020, Volume: 105 Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Cholinesterase Inhibitors; Drug Design; Enzyme Activation; Hep G2 Cells; Humans; Molecular Docking Simulation; Molecular Structure; Protein Binding; Tacrine; Thiadiazoles	2020