tacrine and acetazolamide

tacrine has been researched along with acetazolamide in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's7 (53.85)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Durdagi, S; Göksu, S; Gülçin, İ; Özgeriş, B; Polat Köse, L; Salmas, RE; Supuran, CT; Tümer, F1
Ibrar, A; Khan, I; Saeed, F; Shehzadi, SA1
Amoroso, R; Carradori, S; De Filippis, B; Fantacuzzi, M1
Biçer, A; Gülçin, I; Serdar Gültekin, M; Taslimi, P; Turgut Cin, G; Yakalı, G1
Akalın Çiftçi, G; Altıntop, MD; Beydemir, Ş; Demir, Y; Sever, B; Türkeş, C1
Arslan, M; Beydemir, Ş; Demir, Y; Ereminsoy, E; Güleç, Ö; Hacımüftüoğlu, A; Küfrevioğlu, Öİ; Türkeş, C; Yeni, Y1
Alagöz, MA; Bora, RE; Genc Bilgicli, H; Gulcin, İ; Üç, EM; Zengin, M1

Reviews

2 review(s) available for tacrine and acetazolamide

ArticleYear
Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery.
    Bioorganic & medicinal chemistry, 2018, 07-30, Volume: 26, Issue:13

    Topics: Aldehyde Reductase; Alkaline Phosphatase; Cholinesterases; Coumarins; Drug Design; Enzymes; Glucosidases; Humans; Molecular Docking Simulation; Monoamine Oxidase

2018
Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy.
    European journal of medicinal chemistry, 2022, Apr-05, Volume: 233

    Topics: Humans; Neurodegenerative Diseases; Polyphenols; Resveratrol; Stilbenes; Structure-Activity Relationship

2022

Other Studies

11 other study(ies) available for tacrine and acetazolamide

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds.
    Bioorganic & medicinal chemistry, 2016, 05-15, Volume: 24, Issue:10

    Topics: Acetylcholinesterase; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Structure-Activity Relationship; Sulfonamides; Tetrahydronaphthalenes; Urea

2016
Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes.
    Bioorganic chemistry, 2019, Volume: 82

    Topics: Acetazolamide; Acetylcholinesterase; Butyrylcholinesterase; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cholinesterase Inhibitors; Crystallography, X-Ray; Cyclohexanones; Humans; Kinetics; Molecular Structure; Sulfides; Tacrine

2019
Novel metabolic enzyme inhibitors designed through the molecular hybridization of thiazole and pyrazoline scaffolds.
    Archiv der Pharmazie, 2021, Volume: 354, Issue:12

    Topics: Acetazolamide; Animals; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cell Line; Cholinesterase Inhibitors; Fibroblasts; Humans; Mice; Pyrazoles; Structure-Activity Relationship; Tacrine; Thiazoles

2021
Cytotoxic effect, enzyme inhibition, and in silico studies of some novel N-substituted sulfonyl amides incorporating 1,3,4-oxadiazol structural motif.
    Molecular diversity, 2022, Volume: 26, Issue:5

    Topics: Acetazolamide; Acetylcholinesterase; Amides; Anticonvulsants; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cholinesterase Inhibitors; Diuretics; Humans; Molecular Structure; Neuroblastoma; Structure-Activity Relationship; Tacrine

2022
Synthesis, characterization, evaluation of metabolic enzyme inhibitors and in silico studies of thymol based 2-amino thiol and sulfonic acid compounds.
    Chemico-biological interactions, 2022, Oct-01, Volume: 366

    Topics: Acetazolamide; Acetylcholinesterase; Butyrylcholinesterase; Carbonic Anhydrase I; Carbonic Anhydrase Inhibitors; Cholinesterase Inhibitors; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfonic Acids; Tacrine; Thymol

2022